Murcko scaffold
2-Azaspiro[3.5]nonane scaffold
125 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 9
- Chemicals
- 125
- With full pages
- 14
Scaffold SMILES
C1CCC2(CC1)CNC2
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 125 chemicals
![tert-Butyl 1-(hydroxymethyl)-2-azaspiro[3.5]nonane-2-carboxylate chemical structure, C14H25NO3, CAS 247089-11-8](/s/TZAGSPVJHJQFHP-UHFFFAOYSA-N.svg)
tert-Butyl 1-(hydroxymethyl)-2-azaspiro[3.5]nonane-2-carboxylate
CAS 247089-11-8C14H25NO3
![2-Azaspiro[3.5]nonane-1-carboxylic acid chemical structure, C9H15NO2, CAS 759444-46-7](/s/FPFWJAOAPTZRDJ-UHFFFAOYSA-N.svg)
2-Azaspiro[3.5]nonane-1-carboxylic acid
CAS 759444-46-7C9H15NO2
![2-Azaspiro[3.5]nonan-2-ol chemical structure, C8H15NO, CAS 118975-53-4](/s/CFIOAGNMPKOVEI-UHFFFAOYSA-N.svg)
2-Azaspiro[3.5]nonan-2-ol
CAS 118975-53-4C8H15NO
![2-Azaspiro[3.5]nonane chemical structure, C8H15N, CAS 666-08-0](/s/IBODJKKYTBNWTD-UHFFFAOYSA-N.svg)
2-Azaspiro[3.5]nonane
CAS 666-08-0C8H15N
![2-[(tert-Butoxy)carbonyl]-2-azaspiro[3.5]nonane-1-carboxylic acid chemical structure, C14H23NO4, CAS 247089-12-9](/s/OHJIGVFPIGCIDA-UHFFFAOYSA-N.svg)
2-[(tert-Butoxy)carbonyl]-2-azaspiro[3.5]nonane-1-carboxylic acid
CAS 247089-12-9C14H23NO4
![tert-Butyl 7-hydroxy-2-azaspiro[3.5]nonane-2-carboxylate chemical structure, C13H23NO3, CAS 1363383-18-9](/s/NQHGYUZNWXIZID-UHFFFAOYSA-N.svg)
tert-Butyl 7-hydroxy-2-azaspiro[3.5]nonane-2-carboxylate
CAS 1363383-18-9C13H23NO3
![2-(tert-Butoxycarbonyl)-2-azaspiro[3.5]nonane-7-carboxylic acid chemical structure, C14H23NO4, CAS 1363381-18-3](/s/CGBNTOUUTCHHQO-UHFFFAOYSA-N.svg)
2-(tert-Butoxycarbonyl)-2-azaspiro[3.5]nonane-7-carboxylic acid
CAS 1363381-18-3C14H23NO4
![tert-Butyl 7-amino-2-azaspiro[3.5]nonane-2-carboxylate chemical structure, C13H24N2O2, CAS 1408075-19-3](/s/QODLWXAMPOHERW-UHFFFAOYSA-N.svg)
tert-Butyl 7-amino-2-azaspiro[3.5]nonane-2-carboxylate
CAS 1408075-19-3C13H24N2O2
![tert-Butyl 7-cyano-2-azaspiro[3.5]nonane-2-carboxylate chemical structure, C14H22N2O2, CAS 1434141-70-4](/s/GWUDSHDTYDQWHP-UHFFFAOYSA-N.svg)
tert-Butyl 7-cyano-2-azaspiro[3.5]nonane-2-carboxylate
CAS 1434141-70-4C14H22N2O2
![2-Azaspiro[3.5]nonan-2-amine chemical structure, C8H16N2, CAS 1549329-83-0](/s/JESHNRXPYSGZAO-UHFFFAOYSA-N.svg)
2-Azaspiro[3.5]nonan-2-amine
CAS 1549329-83-0C8H16N2
![7-Methyl-2-azaspiro[3.5]nonane chemical structure, C9H17N, CAS 1782285-74-8](/s/KXYOKWKFIAEHHA-UHFFFAOYSA-N.svg)
7-Methyl-2-azaspiro[3.5]nonane
CAS 1782285-74-8C9H17N
![2-Azaspiro[3.5]nonane hydrochloride chemical structure, C8H16ClN, CAS 1303968-07-1](/s/XNCHACXHZLHDOE-UHFFFAOYSA-N.svg)
2-Azaspiro[3.5]nonane hydrochloride
CAS 1303968-07-1C8H16ClN
![tert-Butyl 7-((methylsulfonyl)oxy)-2-azaspiro[3.5]nonane-2-carboxylate chemical structure, C14H25NO5S, CAS 1421270-78-1](/s/UPELAIVWMIAOKH-UHFFFAOYSA-N.svg)
tert-Butyl 7-((methylsulfonyl)oxy)-2-azaspiro[3.5]nonane-2-carboxylate
CAS 1421270-78-1C14H25NO5S
![2-Azaspiro[3.5]nonane hydrobromide chemical structure, C8H16BrN, CAS 1820706-74-8](/s/XRISAACODSESPW-UHFFFAOYSA-N.svg)
2-Azaspiro[3.5]nonane hydrobromide
CAS 1820706-74-8C8H16BrN
![2-Azaspiro[3.5]nonan-7-ol chemical structure, C8H15NO, CAS 1434141-67-9](/s/CARZJFHAFKTUQP-UHFFFAOYSA-N.svg)
2-Azaspiro[3.5]nonan-7-ol
CAS 1434141-67-9C8H15NO
![tert-Butyl 7-(hydroxymethyl)-2-azaspiro[3.5]nonane-2-carboxylate chemical structure, C14H25NO3, CAS 1434141-69-1](/s/YYOYIBYKZDYMGL-UHFFFAOYSA-N.svg)
tert-Butyl 7-(hydroxymethyl)-2-azaspiro[3.5]nonane-2-carboxylate
CAS 1434141-69-1C14H25NO3
![7-(Boc-amino)-2-azaspiro[3.5]nonane chemical structure, C13H24N2O2, CAS 1434142-07-0](/s/KWNIJIQOTYZDGU-UHFFFAOYSA-N.svg)
7-(Boc-amino)-2-azaspiro[3.5]nonane
CAS 1434142-07-0C13H24N2O2
![tert-Butyl 7-ethynyl-2-azaspiro[3.5]nonane-2-carboxylate chemical structure, C15H23NO2, CAS 1434142-19-4](/s/FXFMKMMGGBYUHW-UHFFFAOYSA-N.svg)
tert-Butyl 7-ethynyl-2-azaspiro[3.5]nonane-2-carboxylate
CAS 1434142-19-4C15H23NO2
![tert-Butyl 7-formyl-2-azaspiro[3.5]nonane-2-carboxylate chemical structure, C14H23NO3, CAS 1434142-21-8](/s/DENTZXANSHPNOQ-UHFFFAOYSA-N.svg)
tert-Butyl 7-formyl-2-azaspiro[3.5]nonane-2-carboxylate
CAS 1434142-21-8C14H23NO3
![tert-Butyl 7-(aminomethyl)-2-azaspiro[3.5]nonane-2-carboxylate chemical structure, C14H26N2O2, CAS 1638767-03-9](/s/LZCPOQCBHNGQKM-UHFFFAOYSA-N.svg)
tert-Butyl 7-(aminomethyl)-2-azaspiro[3.5]nonane-2-carboxylate
CAS 1638767-03-9C14H26N2O2
![2-(Methylsulfonyl)-2-azaspiro[3.5]nonan-7-ol chemical structure, C9H17NO3S, CAS 2092583-32-7](/s/RHUZOPFZOAPAES-UHFFFAOYSA-N.svg)
2-(Methylsulfonyl)-2-azaspiro[3.5]nonan-7-ol
CAS 2092583-32-7C9H17NO3S
![1-(Propan-2-yl)-2-azaspiro[3.5]nonane chemical structure, C11H21N, CAS 1864616-90-9](/s/ZKZGFGJXRDBFRR-UHFFFAOYSA-N.svg)
1-(Propan-2-yl)-2-azaspiro[3.5]nonane
CAS 1864616-90-9C11H21N
![2-Azaspiro[3.5]nonane-2-carboxamide chemical structure, C9H16N2O, CAS 1862780-74-2](/s/QTGWHIGHTBIYOF-UHFFFAOYSA-N.svg)
2-Azaspiro[3.5]nonane-2-carboxamide
CAS 1862780-74-2C9H16N2O
![2-Azaspiro[3.5]nonane-7-carboxylic acid chemical structure, C9H15NO2, CAS 1935601-47-0](/s/YFRJILGFZYLORQ-UHFFFAOYSA-N.svg)
2-Azaspiro[3.5]nonane-7-carboxylic acid
CAS 1935601-47-0C9H15NO2
- Methyl 7,7-dimethyl-2-azaspiro[3.5]nonane-1-carboxylate2059933-30-9C12H21NO2
- Methyl 7-methyl-2-azaspiro[3.5]nonane-1-carboxylate2059931-66-5C11H19NO2
- Methyl 2-azaspiro[3.5]nonane-1-carboxylate2059938-10-0C10H17NO2
- Methyl 7-methoxy-2-azaspiro[3.5]nonane-1-carboxylate2059935-23-6C11H19NO3
- Methyl 7,7-difluoro-2-azaspiro[3.5]nonane-1-carboxylate2059931-70-1C10H15F2NO2
- 7-Fluoro-2-azaspiro[3.5]nonane2091299-06-6C8H14FN
- 1-(3-Propan-2-yl-2-azaspiro[3.5]nonan-2-yl)prop-2-en-1-one2176573-17-2C14H23NO
- 2-Azaspiro[3.5]nonan-7-amine2680663-32-3C8H16N2
- 1-{2-Azaspiro[3.5]nonan-2-yl}prop-2-en-1-one2224473-17-8C11H17NO
- Methyl 6-methoxy-2-azaspiro[3.5]nonane-1-carboxylate2059926-61-1C11H19NO3
- Methyl 7-(trifluoromethyl)-2-azaspiro[3.5]nonane-1-carboxylate2059936-48-8C11H16F3NO2
- Methyl 6-(trifluoromethyl)-2-azaspiro[3.5]nonane-1-carboxylate2059933-40-1C11H16F3NO2
- Methyl 6,6-difluoro-2-azaspiro[3.5]nonane-1-carboxylate2059934-15-3C10H15F2NO2
- Methyl 6,6-dimethyl-2-azaspiro[3.5]nonane-1-carboxylate2059938-20-2C12H21NO2
- 7,7-Difluoro-2-azaspiro(3.5)nonane, trifluoroacetic acid2228781-03-9C10H14F5NO2
- 7,7-Difluoro-2-azaspiro(3.5)nonane2169167-41-1C8H13F2N
- tert-Butyl 7-amino-2-azaspiro(3.5)nonane-2-carboxylate hydrochloride2241139-81-9C13H25ClN2O2
- tert-Butyl 5-hydroxy-2-azaspiro[3.5]nonane-2-carboxylate2168336-04-5C13H23NO3
- tert-Butyl 6-amino-2-azaspiro[3.5]nonane-2-carboxylate2168997-21-3C13H24N2O2
- tert-Butyl 6-hydroxy-2-azaspiro[3.5]nonane-2-carboxylate2168171-77-3C13H23NO3
- tert-Butyl 5-amino-2-azaspiro[3.5]nonane-2-carboxylate2169309-12-8C13H24N2O2
- Methyl(2-{7-methyl-2-azaspiro[3.5]nonan-2-yl}ethyl)amine2138214-39-6C12H24N2
- 2-Azaspiro[3.5]nonan-7-ol hydrochloride2306275-14-7C8H16ClNO
- tert-Butyl 7-(aminomethyl)-2-azaspiro[3.5]nonane-2-carboxylate hydrochloride2413876-51-2C14H27ClN2O2
Related scaffolds
Same ring framework with different atoms or bond orders
C1CC2(C1)CCNCC241 chemicals
C1CCC2(CC1)CCC238 chemicals
C1CC2(C1)CCOCC229 chemicals
C1CNCC2(C1)CCC228 chemicals
C1CCC2(CCC2)OC126 chemicals
C1CC2(C1)CNCCO219 chemicals
C1CC2(CCN1)CNC215 chemicals
C1CCC2(CCC2)NC114 chemicals
C1CCC2(CC1)CCN212 chemicals
C1COCC2(C1)CCC210 chemicals
C1CC2(C1)COCCN210 chemicals
C1CC2(CCO1)CNC210 chemicals