Murcko scaffold
5-Oxa-8-azaspiro(3.5)nonane scaffold
168 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 9
- Chemicals
- 168
- With full pages
- 19
Scaffold SMILES
C1CC2(C1)CNCCO2
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 168 chemicals
5-Oxa-8-azaspiro(3.5)nonane
CAS 220291-93-0C7H13NO
![cis-8-tert-Butoxycarbonyl-5-oxa-8-azaspiro[3.5]nonane-2-carboxylic acid chemical structure, C13H21NO5, CAS 1250999-58-6](/s/SNQOPXQCPPPDIW-UHFFFAOYSA-N.svg)
cis-8-tert-Butoxycarbonyl-5-oxa-8-azaspiro[3.5]nonane-2-carboxylic acid
CAS 1250999-58-6C13H21NO5
![tert-Butyl 2-amino-5-oxa-8-azaspiro[3.5]nonane-8-carboxylate chemical structure, C12H22N2O3, CAS 1251020-91-3](/s/ZGVAOJSQBHREQS-UHFFFAOYSA-N.svg)
tert-Butyl 2-amino-5-oxa-8-azaspiro[3.5]nonane-8-carboxylate
CAS 1251020-91-3C12H22N2O3
![6-Methyl-5-oxa-8-azaspiro[3.5]nonane chemical structure, C8H15NO, CAS 1482133-58-3](/s/GVFWFJBFIIIDFW-UHFFFAOYSA-N.svg)
6-Methyl-5-oxa-8-azaspiro[3.5]nonane
CAS 1482133-58-3C8H15NO
![6,6-Dimethyl-5-oxa-8-azaspiro[3.5]nonane chemical structure, C9H17NO, CAS 1488555-93-6](/s/NJELGSWWDXDPIC-UHFFFAOYSA-N.svg)
6,6-Dimethyl-5-oxa-8-azaspiro[3.5]nonane
CAS 1488555-93-6C9H17NO
![7-Methyl-5-oxa-8-azaspiro[3.5]nonane chemical structure, C8H15NO, CAS 1557979-23-3](/s/VCJVTYOVJIOUIP-UHFFFAOYSA-N.svg)
7-Methyl-5-oxa-8-azaspiro[3.5]nonane
CAS 1557979-23-3C8H15NO
![2-Methyl-5-oxa-8-azaspiro[3.5]nonane chemical structure, C8H15NO, CAS 1696675-06-5](/s/LUBBHIAIDMWQHW-UHFFFAOYSA-N.svg)
2-Methyl-5-oxa-8-azaspiro[3.5]nonane
CAS 1696675-06-5C8H15NO
![2-Methoxy-6-methyl-5-oxa-8-azaspiro[3.5]nonane chemical structure, C9H17NO2, CAS 1692404-73-1](/s/SEXCKAHWUOFKPD-UHFFFAOYSA-N.svg)
2-Methoxy-6-methyl-5-oxa-8-azaspiro[3.5]nonane
CAS 1692404-73-1C9H17NO2
![9-Methyl-5-oxa-8-azaspiro[3.5]nonane chemical structure, C8H15NO, CAS 2172495-18-8](/s/YRLHEGQTYJWEPV-UHFFFAOYSA-N.svg)
9-Methyl-5-oxa-8-azaspiro[3.5]nonane
CAS 2172495-18-8C8H15NO
![(R)-7-Methyl-5-oxa-8-azaspiro[3.5]nonane chemical structure, C8H15NO, CAS 2920232-61-5](/s/VCJVTYOVJIOUIP-SSDOTTSWSA-N.svg)
(R)-7-Methyl-5-oxa-8-azaspiro[3.5]nonane
CAS 2920232-61-5C8H15NO
![(S)-7-Methyl-5-oxa-8-azaspiro[3.5]nonane chemical structure, C8H15NO, CAS 2309427-31-2](/s/VCJVTYOVJIOUIP-ZETCQYMHSA-N.svg)
(S)-7-Methyl-5-oxa-8-azaspiro[3.5]nonane
CAS 2309427-31-2C8H15NO
![2,2-Dimethyl-5-oxa-8-azaspiro[3.5]nonane chemical structure, C9H17NO, CAS 1936194-14-7](/s/VOBBDTKDOOBEGV-UHFFFAOYSA-N.svg)
2,2-Dimethyl-5-oxa-8-azaspiro[3.5]nonane
CAS 1936194-14-7C9H17NO
![8-(2-Methylprop-2-en-1-yl)-5-oxa-8-azaspiro[3.5]nonane chemical structure, C11H19NO, CAS 1865128-60-4](/s/YYOYUOWDCOWRCC-UHFFFAOYSA-N.svg)
8-(2-Methylprop-2-en-1-yl)-5-oxa-8-azaspiro[3.5]nonane
CAS 1865128-60-4C11H19NO
8-(But-2-yn-1-yl)-5-oxa-8-azaspiro(3.5)nonane
CAS 1864804-63-6C11H17NO
![1-Methyl-5-oxa-8-azaspiro[3.5]nonane chemical structure, C8H15NO, CAS 1849210-27-0](/s/DGAVQGREXXTVNM-UHFFFAOYSA-N.svg)
1-Methyl-5-oxa-8-azaspiro[3.5]nonane
CAS 1849210-27-0C8H15NO
![2-{5-Oxa-8-azaspiro[3.5]nonan-8-yl}ethan-1-amine chemical structure, C9H18N2O, CAS 1877653-59-2](/s/REGQJXDQUJKNQW-UHFFFAOYSA-N.svg)
2-{5-Oxa-8-azaspiro[3.5]nonan-8-yl}ethan-1-amine
CAS 1877653-59-2C9H18N2O
![5-Oxa-8-azaspiro[3.5]nonane-8-carboxamide chemical structure, C8H14N2O2, CAS 1872838-01-1](/s/YFJJYHSSBMAKGV-UHFFFAOYSA-N.svg)
5-Oxa-8-azaspiro[3.5]nonane-8-carboxamide
CAS 1872838-01-1C8H14N2O2
![5-Oxa-8-azaspiro[3.5]nonane hydrochloride chemical structure, C7H14ClNO, CAS 2206813-84-3](/s/NISGVYLNIIGTDG-UHFFFAOYSA-N.svg)
5-Oxa-8-azaspiro[3.5]nonane hydrochloride
CAS 2206813-84-3C7H14ClNO
![1-(6-Methyl-5-oxa-8-azaspiro[3.5]nonan-8-yl)prop-2-en-1-one chemical structure, C11H17NO2, CAS 2190141-50-3](/s/PNYDTXFKAKOPES-UHFFFAOYSA-N.svg)
1-(6-Methyl-5-oxa-8-azaspiro[3.5]nonan-8-yl)prop-2-en-1-one
CAS 2190141-50-3C11H17NO2
![8-[(tert-Butoxy)carbonyl]-5-oxa-8-azaspiro[3.5]nonane-6-carboxylic acid chemical structure, C13H21NO5, CAS 2305252-49-5](/s/JPIDIOMIWPPKGO-UHFFFAOYSA-N.svg)
8-[(tert-Butoxy)carbonyl]-5-oxa-8-azaspiro[3.5]nonane-6-carboxylic acid
CAS 2305252-49-5C13H21NO5
![5-Oxa-8-azaspiro[3.5]nonane-6-carboxylic acid hydrochloride chemical structure, C8H14ClNO3, CAS 2305255-37-0](/s/OQQBLHNAPLTWDQ-UHFFFAOYSA-N.svg)
5-Oxa-8-azaspiro[3.5]nonane-6-carboxylic acid hydrochloride
CAS 2305255-37-0C8H14ClNO3
![5-Oxa-8-azaspiro[3.5]nonane-6-carboxylic acid chemical structure, C8H13NO3, CAS 2305253-04-5](/s/NNSINUBLLVXPST-UHFFFAOYSA-N.svg)
5-Oxa-8-azaspiro[3.5]nonane-6-carboxylic acid
CAS 2305253-04-5C8H13NO3
![Methyl 5-oxa-8-azaspiro[3.5]nonane-6-carboxylate chemical structure, C9H15NO3, CAS 2305252-04-2](/s/DFLZMQADBFKGOY-UHFFFAOYSA-N.svg)
Methyl 5-oxa-8-azaspiro[3.5]nonane-6-carboxylate
CAS 2305252-04-2C9H15NO3
![tert-Butyl 6-(iodomethyl)-5-oxa-8-azaspiro[3.5]nonane-8-carboxylate chemical structure, C13H22INO3, CAS 2168788-43-8](/s/UCDOSHOSLWSXTK-UHFFFAOYSA-N.svg)
tert-Butyl 6-(iodomethyl)-5-oxa-8-azaspiro[3.5]nonane-8-carboxylate
CAS 2168788-43-8C13H22INO3
- (5-Oxa-8-azaspiro(3.5)nonan-6-yl)methanol2305255-35-8C8H15NO2
- tert-Butyl 6-(aminomethyl)-5-oxa-8-azaspiro[3.5]nonane-8-carboxylate2169022-82-4C13H24N2O3
- 2-(8-((tert-Butoxy)carbonyl)-5-oxa-8-azaspiro(3.5)nonan-6-yl)acetic acid2309469-39-2C14H23NO5
- 2-{5-Oxa-8-azaspiro[3.5]nonan-6-yl}acetic acid hydrochloride2309462-43-7C9H16ClNO3
- 2-{5-Oxa-8-azaspiro[3.5]nonan-6-yl}acetic acid2309462-42-6C9H15NO3
- Methyl 2-{5-oxa-8-azaspiro[3.5]nonan-6-yl}acetate2309444-73-1C10H17NO3
- N-Ethyl-N-[2-(5-oxa-8-azaspiro[3.5]nonan-8-yl)-2-oxoethyl]prop-2-enamide2361721-48-2C14H22N2O3
- 2-(8-((tert-Butoxy)carbonyl)-5-oxa-8-azaspiro(3.5)nonan-7-yl)acetic acid2408972-75-6C14H23NO5
- 8-[(tert-Butoxy)carbonyl]-5-oxa-8-azaspiro[3.5]nonane-7-carboxylicacid2416235-83-9C13H21NO5
- tert-Butyl 2-hydroxy-5-oxa-8-azaspiro[3.5]nonane-8-carboxylate2309427-24-3C12H21NO4
- 5-Oxa-8-azaspiro[3.5]nonane-9-carboxylic acid hydrochloride2460755-71-7C8H14ClNO3
- 5-Oxa-8-azaspiro[3.5]nonane-9-carboxylic acid2460755-31-9C8H13NO3
- 8-[(tert-Butoxy)carbonyl]-5-oxa-8-azaspiro[3.5]nonane-9-carboxylic acid2460756-35-6C13H21NO5
- 5-Oxa-8-azaspiro[3.5]nonan-9-ylmethanol, hydrochloride2470440-85-6C8H16ClNO2
- {5-Oxa-8-azaspiro[3.5]nonan-9-yl}methanol2470440-84-5C8H15NO2
- 5-Oxa-8-azaspiro[3.5]nonan-2-ol2309427-25-4C7H13NO2
- 2,2-Difluoro-5-oxa-8-azaspiro[3.5]nonane2302959-91-5C7H11F2NO
- Methyl 5-oxa-8-azaspiro(3.5)nonane-9-carboxylate hydrochloride2470439-77-9C9H16ClNO3
- Methyl 5-oxa-8-azaspiro[3.5]nonane-9-carboxylate2470439-76-8C9H15NO3
- Methyl5-oxa-8-azaspiro[3.5]nonane-7-carboxylatehydrochloride2503202-05-7C9H16ClNO3
- Methyl 5-oxa-8-azaspiro[3.5]nonane-7-carboxylate2503202-04-6C9H15NO3
- tert-Butyl 7-formyl-5-oxa-8-azaspiro(3.5)nonane-8-carboxylate2567496-92-6C13H21NO4
- tert-Butyl cis-2-(hydroxymethyl)-5-oxa-8-azaspiro[3.5]nonane-8-carboxylate2725791-12-6C13H23NO4
- tert-Butyl 2-(iodomethyl)-5-oxa-8-azaspiro[3.5]nonane-8-carboxylate2920395-79-3C13H22INO3
Related scaffolds
Same ring framework with different atoms or bond orders
C1CC2(C1)CCNCC241 chemicals
C1CCC2(CC1)CCC238 chemicals
C1CC2(C1)CCOCC229 chemicals
C1CNCC2(C1)CCC228 chemicals
C1CCC2(CCC2)OC126 chemicals
C1CC2(CCN1)CNC215 chemicals
C1CCC2(CC1)CNC214 chemicals
C1CCC2(CCC2)NC114 chemicals
C1CCC2(CC1)CCN212 chemicals
C1COCC2(C1)CCC210 chemicals
C1CC2(C1)COCCN210 chemicals
C1CC2(CCO1)CNC210 chemicals