Murcko scaffold
5-Oxaspiro[3.5]nonane scaffold
127 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 9
- Chemicals
- 127
- With full pages
- 26
Scaffold SMILES
C1CCC2(CCC2)OC1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 127 chemicals
![5-Oxaspiro[3.5]nonane-2-carboxylic acid chemical structure, C9H14O3, CAS 1374659-09-2](/s/YXJQEKYNPLVKTG-UHFFFAOYSA-N.svg)
5-Oxaspiro[3.5]nonane-2-carboxylic acid
CAS 1374659-09-2C9H14O3
5-Oxaspiro(3.5)nonan-8-amine
CAS 1309434-30-7C8H15NO
![5-Oxaspiro[3.5]nonane chemical structure, C8H14O, CAS 185-14-8](/s/PZRIKVOGVZVHES-UHFFFAOYSA-N.svg)
5-Oxaspiro[3.5]nonane
CAS 185-14-8C8H14O
![5-Oxaspiro[3.5]nonan-8-yl methanesulfonate chemical structure, C9H16O4S, CAS 1309366-15-1](/s/MNPRXHRNZZNZQT-UHFFFAOYSA-N.svg)
5-Oxaspiro[3.5]nonan-8-yl methanesulfonate
CAS 1309366-15-1C9H16O4S
![2-Amino-2-{5-oxaspiro[3.5]nonan-8-yl}acetic acid hydrochloride chemical structure, C10H18ClNO3, CAS 1607249-39-7](/s/BBKYCJIMUZXJMK-UHFFFAOYSA-N.svg)
2-Amino-2-{5-oxaspiro[3.5]nonan-8-yl}acetic acid hydrochloride
CAS 1607249-39-7C10H18ClNO3
![2-Amino-2-(5-oxaspiro[3.5]nonan-8-yl)acetic acid chemical structure, C10H17NO3, CAS 1526731-85-0](/s/GNLBTSUUPGNIPG-UHFFFAOYSA-N.svg)
2-Amino-2-(5-oxaspiro[3.5]nonan-8-yl)acetic acid
CAS 1526731-85-0C10H17NO3
![5-Oxaspiro[3.5]nonane-8-sulfonamide chemical structure, C8H15NO3S, CAS 1515376-92-7](/s/AIDPIVMZRXLPKZ-UHFFFAOYSA-N.svg)
5-Oxaspiro[3.5]nonane-8-sulfonamide
CAS 1515376-92-7C8H15NO3S
![8-Azido-5-oxaspiro[3.5]nonane chemical structure, C8H13N3O, CAS 1309366-16-2](/s/CLTCSXJQVAPAQH-UHFFFAOYSA-N.svg)
8-Azido-5-oxaspiro[3.5]nonane
CAS 1309366-16-2C8H13N3O
![{5-Oxaspiro[3.5]nonan-8-yl}hydrazine chemical structure, C8H16N2O, CAS 1527804-99-4](/s/XPJXWAFUVRJBIC-UHFFFAOYSA-N.svg)
{5-Oxaspiro[3.5]nonan-8-yl}hydrazine
CAS 1527804-99-4C8H16N2O
![N-Methyl-5-oxaspiro[3.5]nonan-8-amine chemical structure, C9H17NO, CAS 1525137-87-4](/s/JVYRKVDZHSDIPT-UHFFFAOYSA-N.svg)
N-Methyl-5-oxaspiro[3.5]nonan-8-amine
CAS 1525137-87-4C9H17NO
![2-(5-Oxaspiro[3.5]nonan-8-yl)acetic acid chemical structure, C10H16O3, CAS 1369152-09-9](/s/JMLLGPTZXJDAIE-UHFFFAOYSA-N.svg)
2-(5-Oxaspiro[3.5]nonan-8-yl)acetic acid
CAS 1369152-09-9C10H16O3
![5-Oxaspiro[3.5]nonan-8-ol chemical structure, C8H14O2, CAS 1368181-23-0](/s/JLPBRBGFJSBHSH-UHFFFAOYSA-N.svg)
5-Oxaspiro[3.5]nonan-8-ol
CAS 1368181-23-0C8H14O2
![2-{[(tert-Butoxy)carbonyl]amino}-2-{5-oxaspiro[3.5]nonan-8-yl}acetic acid chemical structure, C15H25NO5, CAS 1536830-28-0](/s/MZIIRQUZZJBOIV-UHFFFAOYSA-N.svg)
2-{[(tert-Butoxy)carbonyl]amino}-2-{5-oxaspiro[3.5]nonan-8-yl}acetic acid
CAS 1536830-28-0C15H25NO5
![5-Oxaspiro[3.5]nonane-8-carbonitrile chemical structure, C9H13NO, CAS 1503527-20-5](/s/HZVTYMSWVCWFEU-UHFFFAOYSA-N.svg)
5-Oxaspiro[3.5]nonane-8-carbonitrile
CAS 1503527-20-5C9H13NO
![5-Oxaspiro[3.5]nonane-8-carboxylic acid chemical structure, C9H14O3, CAS 1468691-26-0](/s/HQXAMOGHZYMCPZ-UHFFFAOYSA-N.svg)
5-Oxaspiro[3.5]nonane-8-carboxylic acid
CAS 1468691-26-0C9H14O3
![{5-Oxaspiro[3.5]nonan-8-yl}methanamine chemical structure, C9H17NO, CAS 1466289-20-2](/s/QDOLICQFKUYSJC-UHFFFAOYSA-N.svg)
{5-Oxaspiro[3.5]nonan-8-yl}methanamine
CAS 1466289-20-2C9H17NO
![5-Oxaspiro[3.5]nonane-8-sulfonyl chloride chemical structure, C8H13ClO3S, CAS 1518133-79-3](/s/RKKNVNLREIVIRM-UHFFFAOYSA-N.svg)
5-Oxaspiro[3.5]nonane-8-sulfonyl chloride
CAS 1518133-79-3C8H13ClO3S
![Methyl 2-amino-2-{5-oxaspiro[3.5]nonan-8-yl}acetate chemical structure, C11H19NO3, CAS 1513663-21-2](/s/ZDLBBWMGXFLTOZ-UHFFFAOYSA-N.svg)
Methyl 2-amino-2-{5-oxaspiro[3.5]nonan-8-yl}acetate
CAS 1513663-21-2C11H19NO3
![Ethyl 2-amino-2-{5-oxaspiro[3.5]nonan-8-yl}acetate chemical structure, C12H21NO3, CAS 1510012-11-9](/s/ZWTCTJZJMYXORW-UHFFFAOYSA-N.svg)
Ethyl 2-amino-2-{5-oxaspiro[3.5]nonan-8-yl}acetate
CAS 1510012-11-9C12H21NO3
![2-Acetamido-2-{5-oxaspiro[3.5]nonan-8-yl}acetic acid chemical structure, C12H19NO4, CAS 1501036-93-6](/s/RVJCYGDNXKDCMN-UHFFFAOYSA-N.svg)
2-Acetamido-2-{5-oxaspiro[3.5]nonan-8-yl}acetic acid
CAS 1501036-93-6C12H19NO4
![1-(5-Oxaspiro[3.5]nonan-8-yl)ethan-1-one chemical structure, C10H16O2, CAS 1515737-49-1](/s/INRVQNPYMHQNOG-UHFFFAOYSA-N.svg)
1-(5-Oxaspiro[3.5]nonan-8-yl)ethan-1-one
CAS 1515737-49-1C10H16O2
![1-(5-Oxaspiro[3.5]nonan-8-yl)ethan-1-ol chemical structure, C10H18O2, CAS 1533051-78-3](/s/LBOUWVBSLNRQMQ-UHFFFAOYSA-N.svg)
1-(5-Oxaspiro[3.5]nonan-8-yl)ethan-1-ol
CAS 1533051-78-3C10H18O2
![5-Oxaspiro[3.5]nonan-8-ylmethanol chemical structure, C9H16O2, CAS 1501084-95-2](/s/QZLKWBKONMBIEU-UHFFFAOYSA-N.svg)
5-Oxaspiro[3.5]nonan-8-ylmethanol
CAS 1501084-95-2C9H16O2
![2-{5-Oxaspiro[3.5]nonan-8-yl}ethan-1-ol chemical structure, C10H18O2, CAS 1508219-31-5](/s/BYHNXUXVEPRMKQ-UHFFFAOYSA-N.svg)
2-{5-Oxaspiro[3.5]nonan-8-yl}ethan-1-ol
CAS 1508219-31-5C10H18O2
- 2-(5-Oxaspiro[3.5]nonan-8-yl)ethan-1-amine1368377-72-3C10H19NO
- 5-Oxaspiro(3.5)nonane-8-carbaldehyde1537697-53-2C9H14O2
- 8-Iodo-5-oxaspiro[3.5]nonane1499449-36-3C8H13IO
- 8-Bromo-5-oxaspiro[3.5]nonane1540079-49-9C8H13BrO
- tert-Butyl 2-amino-2-{5-oxaspiro[3.5]nonan-8-yl}acetate1543648-33-4C14H25NO3
- (R)-5-Oxaspiro[3.5]nonan-8-amine2201704-03-0C8H15NO
- (S)-5-Oxaspiro[3.5]nonan-8-amine2322933-52-6C8H15NO
- 2-Methyl-5-oxaspiro[3.5]nonan-8-ol1702174-53-5C9H16O2
- 2-Methoxy-5-oxaspiro[3.5]nonan-8-ol1699276-14-6C9H16O3
- 5-Oxaspiro(3.5)nonan-8-ylmethanamine hydrochloride1864061-28-8C9H18ClNO
- N-({5-Oxaspiro[3.5]nonan-8-yl}methyl)prop-2-enamide2094558-70-8C12H19NO2
- 5-Oxaspiro[3.5]nonan-8-amine hydrochloride1309366-17-3C8H16ClNO
- 8-Amino-5-oxaspiro[3.5]nonane-2-carboxylic acid hydrochloride2094589-30-5C9H16ClNO3
- 8-Amino-5-oxaspiro[3.5]nonane-2-carboxylic acid2094589-29-2C9H15NO3
- 8-{[(tert-Butoxy)carbonyl]amino}-5-oxaspiro[3.5]nonane-2-carboxylic acid2094498-37-8C14H23NO5
- 5-Oxaspiro[3.5]nonane-8-thiol1849364-99-3C8H14OS
- 5-Oxaspiro(3.5)nonane-6-carbaldehyde1874345-90-0C9H14O2
- 5-Oxaspiro[3.5]nonan-7-amine1823516-17-1C8H15NO
- 6-(Bromomethyl)-5-oxaspiro[3.5]nonane1872681-59-8C9H15BrO
- 6-(Iodomethyl)-5-oxaspiro(3.5)nonane1866138-71-7C9H15IO
- {5-Oxaspiro[3.5]nonan-6-yl}methanamine1862141-42-1C9H17NO
- {5-Oxaspiro[3.5]nonan-6-yl}methanol1874345-95-5C9H16O2
- 5-Oxaspiro[3.5]nonane-6-carboxylic acid1864480-39-6C9H14O3
- 2,2-Dimethyl-5-oxaspiro[3.5]nonan-8-ol1934753-59-9C10H18O2
Related scaffolds
Same ring framework with different atoms or bond orders
C1CC2(C1)CCNCC241 chemicals
C1CCC2(CC1)CCC238 chemicals
C1CC2(C1)CCOCC229 chemicals
C1CNCC2(C1)CCC228 chemicals
C1CC2(C1)CNCCO219 chemicals
C1CC2(CCN1)CNC215 chemicals
C1CCC2(CC1)CNC214 chemicals
C1CCC2(CCC2)NC114 chemicals
C1CCC2(CC1)CCN212 chemicals
C1COCC2(C1)CCC210 chemicals
C1CC2(C1)COCCN210 chemicals
C1CC2(CCO1)CNC210 chemicals