Murcko scaffold
Ring system with 2 rings and 9 atoms
172 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 9
- Chemicals
- 172
- With full pages
- 29
Scaffold SMILES
C1CC2(C1)CCOCC2
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 172 chemicals
![7-Oxaspiro[3.5]nonane-2-carbonitrile chemical structure, C9H13NO, CAS 1374659-07-0](/s/OEMVWPVTTNNRKI-UHFFFAOYSA-N.svg)
7-Oxaspiro[3.5]nonane-2-carbonitrile
CAS 1374659-07-0C9H13NO
7-Oxaspiro(3.5)nonane-2-carboxylic acid
CAS 90612-60-5C9H14O3
![7-Oxaspiro[3.5]nonan-2-amine chemical structure, C8H15NO, CAS 1374658-89-5](/s/ZDTIUHUGDCJDRO-UHFFFAOYSA-N.svg)
7-Oxaspiro[3.5]nonan-2-amine
CAS 1374658-89-5C8H15NO
![3-Oxaspiro[5.3]nonan-2-ol chemical structure, C8H14O2, CAS 518284-71-4](/s/ISGABRFWDQKXFL-UHFFFAOYSA-N.svg)
3-Oxaspiro[5.3]nonan-2-ol
CAS 518284-71-4C8H14O2
![2-Cyano-7-oxaspiro[3.5]nonane-2-carboxylic acid chemical structure, C10H13NO3, CAS 1468873-43-9](/s/MZKRRLGUVDOBQZ-UHFFFAOYSA-N.svg)
2-Cyano-7-oxaspiro[3.5]nonane-2-carboxylic acid
CAS 1468873-43-9C10H13NO3
![2-(Aminomethyl)-7-oxaspiro[3.5]nonane-2-carboxylic acid chemical structure, C10H17NO3, CAS 1497787-90-2](/s/NRXQYPBHVXVQIS-UHFFFAOYSA-N.svg)
2-(Aminomethyl)-7-oxaspiro[3.5]nonane-2-carboxylic acid
CAS 1497787-90-2C10H17NO3
![2-Methanesulfonyl-7-oxaspiro[3.5]nonane-2-carboxylic acid chemical structure, C10H16O5S, CAS 1467420-81-0](/s/CBOXXUVWMJSCHA-UHFFFAOYSA-N.svg)
2-Methanesulfonyl-7-oxaspiro[3.5]nonane-2-carboxylic acid
CAS 1467420-81-0C10H16O5S
![Methyl 2-(aminomethyl)-7-oxaspiro[3.5]nonane-2-carboxylate chemical structure, C11H19NO3, CAS 1480405-71-7](/s/YKPSTTBOKOQJDW-UHFFFAOYSA-N.svg)
Methyl 2-(aminomethyl)-7-oxaspiro[3.5]nonane-2-carboxylate
CAS 1480405-71-7C11H19NO3
![1-{7-Oxaspiro[3.5]nonan-2-yl}methanamine chemical structure, C9H17NO, CAS 1440962-10-6](/s/RTSFVTSFONHDFG-UHFFFAOYSA-N.svg)
1-{7-Oxaspiro[3.5]nonan-2-yl}methanamine
CAS 1440962-10-6C9H17NO
![N-Methyl-1-(7-oxaspiro[3.5]nonan-2-yl)methanamine chemical structure, C10H19NO, CAS 1486447-32-8](/s/VHZPIKCRIQCVRT-UHFFFAOYSA-N.svg)
N-Methyl-1-(7-oxaspiro[3.5]nonan-2-yl)methanamine
CAS 1486447-32-8C10H19NO
![2-(Methylsulfanyl)-7-oxaspiro[3.5]nonane-2-carboxylic acid chemical structure, C10H16O3S, CAS 1480367-89-2](/s/YNGMJACXEIEHHO-UHFFFAOYSA-N.svg)
2-(Methylsulfanyl)-7-oxaspiro[3.5]nonane-2-carboxylic acid
CAS 1480367-89-2C10H16O3S
![2-(Ethylsulfanyl)-7-oxaspiro[3.5]nonane-2-carboxylic acid chemical structure, C11H18O3S, CAS 1496672-97-9](/s/OPVFWHIJQQHGMC-UHFFFAOYSA-N.svg)
2-(Ethylsulfanyl)-7-oxaspiro[3.5]nonane-2-carboxylic acid
CAS 1496672-97-9C11H18O3S
![2-(Isopropylthio)-7-oxaspiro[3.5]nonane-2-carboxylic acid chemical structure, C12H20O3S, CAS 1478304-76-5](/s/YQZXWYPRCKAUEK-UHFFFAOYSA-N.svg)
2-(Isopropylthio)-7-oxaspiro[3.5]nonane-2-carboxylic acid
CAS 1478304-76-5C12H20O3S
7-Oxaspiro(3.5)nonan-1-amine hydrochloride
CAS 1823375-28-5C8H16ClNO
![7-Oxaspiro[3.5]nonan-1-amine chemical structure, C8H15NO, CAS 1781062-62-1](/s/DJZUXFDAFKPNFI-UHFFFAOYSA-N.svg)
7-Oxaspiro[3.5]nonan-1-amine
CAS 1781062-62-1C8H15NO
![7-Oxaspiro[3.5]nonan-1-ol chemical structure, C8H14O2, CAS 1781125-92-5](/s/KFDVBQPCFNZKAS-UHFFFAOYSA-N.svg)
7-Oxaspiro[3.5]nonan-1-ol
CAS 1781125-92-5C8H14O2
![3-Ethoxy-7-oxaspiro[3.5]nonan-1-ol chemical structure, C10H18O3, CAS 1803582-80-0](/s/CHKDSMZFHOZVDI-UHFFFAOYSA-N.svg)
3-Ethoxy-7-oxaspiro[3.5]nonan-1-ol
CAS 1803582-80-0C10H18O3
![3-Ethoxy-7-oxaspiro[3.5]nonan-1-amine chemical structure, C10H19NO2, CAS 1803599-07-6](/s/JUKJNEUBOWFVOM-UHFFFAOYSA-N.svg)
3-Ethoxy-7-oxaspiro[3.5]nonan-1-amine
CAS 1803599-07-6C10H19NO2
7-Oxaspiro(3.5)nonan-2-ol
CAS 1501498-34-5C8H14O2
![N-Methyl-7-oxaspiro[3.5]nonan-2-amine chemical structure, C9H17NO, CAS 1513943-97-9](/s/CPBJHDIUMFMVLZ-UHFFFAOYSA-N.svg)
N-Methyl-7-oxaspiro[3.5]nonan-2-amine
CAS 1513943-97-9C9H17NO
![(3S)-7-Oxaspiro[3.5]nonan-3-amine chemical structure, C8H15NO, CAS 2518281-18-8](/s/DJZUXFDAFKPNFI-ZETCQYMHSA-N.svg)
(3S)-7-Oxaspiro[3.5]nonan-3-amine
CAS 2518281-18-8C8H15NO
![rac-(1R,3R)-3-Ethoxy-7-oxaspiro[3.5]nonan-1-amine chemical structure, C10H19NO2](/s/JUKJNEUBOWFVOM-IUCAKERBSA-N.svg)
rac-(1R,3R)-3-Ethoxy-7-oxaspiro[3.5]nonan-1-amine
C10H19NO2
![Rel-(1R,3R)-3-ethoxy-7-oxaspiro[3.5]nonan-1-amine chemical structure, C10H19NO2, CAS 2137780-75-5](/s/JUKJNEUBOWFVOM-RKDXNWHRSA-N.svg)
Rel-(1R,3R)-3-ethoxy-7-oxaspiro[3.5]nonan-1-amine
CAS 2137780-75-5C10H19NO2
![{7-Oxaspiro[3.5]nonan-1-yl}methanamine chemical structure, C9H17NO, CAS 1780867-73-3](/s/SWYOPHMRNVLUGC-UHFFFAOYSA-N.svg)
{7-Oxaspiro[3.5]nonan-1-yl}methanamine
CAS 1780867-73-3C9H17NO
- 7-Oxaspiro[3.5]nonan-3-ylmethanol1780710-24-8C9H16O2
- 7-Oxaspiro[3.5]nonane-1-carboxylic acid1784418-25-2C9H14O3
- {7-Oxaspiro[3.5]nonan-2-yl}methanol1896810-74-4C9H16O2
- {2-Amino-7-oxaspiro[3.5]nonan-2-yl}methanol1889271-12-8C9H17NO2
- 2-Amino-7-oxaspiro[3.5]nonane-2-carboxylic acid1892462-74-6C9H15NO3
- Methyl 2-amino-7-oxaspiro[3.5]nonane-2-carboxylate1890489-99-2C10H17NO3
- 7-Oxaspiro[3.5]nonane-2,2-dicarboxylic acid91950-60-6C10H14O5
- 2-(Bromomethyl)-7-oxaspiro[3.5]nonane2092717-20-7C9H15BrO
- N-Methoxy-N-methyl-7-oxaspiro[3.5]nonane-2-carboxamide2098113-78-9C11H19NO3
- 2-{[(tert-Butoxy)carbonyl]amino}-7-oxaspiro[3.5]nonane-2-carboxylic acid1823271-75-5C14H23NO5
- Ethyl 2-amino-7-oxaspiro[3.5]nonane-2-carboxylate2092092-87-8C11H19NO3
- tert-Butyl 2-amino-7-oxaspiro[3.5]nonane-2-carboxylate2098068-19-8C13H23NO3
- N-(7-Oxaspiro[3.5]nonan-1-yl)pivalamide2169487-43-6C13H23NO2
- 3-Methyl-N-{7-oxaspiro[3.5]nonan-1-yl}butanamide2168837-43-0C13H23NO2
- {7-Oxaspiro[3.5]nonan-1-yl}methanamine hydrochloride2059987-27-6C9H18ClNO
- 7-Oxaspiro(3.5)nonane-2-carbaldehyde1440962-03-7C9H14O2
- 3,3-Dimethyl-7-oxaspiro[3.5]nonan-1-ol2090435-22-4C10H18O2
- 3-Amino-7-oxaspiro[3.5]nonan-1-ol hydrochloride2138131-75-4C8H16ClNO2
- 3-Amino-7-oxaspiro[3.5]nonan-1-ol2137987-96-1C8H15NO2
- rac-(1S,3R)-3-(tert-Butoxy)-7-oxaspiro[3.5]nonan-1-ol2307774-18-9C12H22O3
- (1S,3R)-3-(tert-Butoxy)-7-oxaspiro[3.5]nonan-1-yl methanesulfonate2126144-58-7C13H24O5S
- rac-(1R,3R)-3-(tert-Butoxy)-7-oxaspiro[3.5]nonan-1-amine hydrochloride2307776-78-7C12H24ClNO2
- rac-(1R,3R)-3-Amino-7-oxaspiro(3.5)nonan-1-ol hydrochloride2126144-46-3C8H16ClNO2
- (1R,3R)-3-Amino-7-oxaspiro[3.5]nonan-1-ol2126144-45-2C8H15NO2
Related scaffolds
Same ring framework with different atoms or bond orders
C1CC2(C1)CCNCC241 chemicals
C1CCC2(CC1)CCC238 chemicals
C1CNCC2(C1)CCC228 chemicals
C1CCC2(CCC2)OC126 chemicals
C1CC2(C1)CNCCO219 chemicals
C1CC2(CCN1)CNC215 chemicals
C1CCC2(CC1)CNC214 chemicals
C1CCC2(CCC2)NC114 chemicals
C1CCC2(CC1)CCN212 chemicals
C1COCC2(C1)CCC210 chemicals
C1CC2(C1)COCCN210 chemicals
C1CC2(CCO1)CNC210 chemicals