Murcko scaffold
Ring system with 2 rings and 9 atoms
136 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 9
- Chemicals
- 136
- With full pages
- 28
Scaffold SMILES
C1CNCC2(C1)CCC2
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 136 chemicals
tert-Butyl N-(6-azaspiro(3.5)nonan-8-yl)carbamate
CAS 1823977-72-5C13H24N2O2
![6-Aza-spiro[3.5]nonane hydrochloride chemical structure, C8H16ClN, CAS 71873-27-3](/s/IELLPRWHLZJJIN-UHFFFAOYSA-N.svg)
6-Aza-spiro[3.5]nonane hydrochloride
CAS 71873-27-3C8H16ClN
![9,9-Difluoro-6-azaspiro[3.5]nonane hydrochloride chemical structure, C8H14ClF2N, CAS 1198285-45-8](/s/LMSIPOFNVAKSFX-UHFFFAOYSA-N.svg)
9,9-Difluoro-6-azaspiro[3.5]nonane hydrochloride
CAS 1198285-45-8C8H14ClF2N
![9,9-Difluoro-6-azaspiro[3.5]nonane chemical structure, C8H13F2N, CAS 1198392-67-4](/s/KXMAKTYMKLVFGK-UHFFFAOYSA-N.svg)
9,9-Difluoro-6-azaspiro[3.5]nonane
CAS 1198392-67-4C8H13F2N
![tert-Butyl 1-amino-3-ethoxy-6-azaspiro[3.5]nonane-6-carboxylate chemical structure, C15H28N2O3, CAS 1354954-65-6](/s/GCAMGINWCAWZCQ-UHFFFAOYSA-N.svg)
tert-Butyl 1-amino-3-ethoxy-6-azaspiro[3.5]nonane-6-carboxylate
CAS 1354954-65-6C15H28N2O3
![tert-Butyl 2-cyano-6-azaspiro[3.5]nonane-6-carboxylate chemical structure, C14H22N2O2, CAS 1374658-96-4](/s/AIUYJUWHTHCCCE-UHFFFAOYSA-N.svg)
tert-Butyl 2-cyano-6-azaspiro[3.5]nonane-6-carboxylate
CAS 1374658-96-4C14H22N2O2
6-((tert-Butoxy)carbonyl)-6-azaspiro(3.5)nonane-2-carboxylic acid
CAS 1374659-03-6C14H23NO4
![tert-Butyl 2-amino-6-azaspiro[3.5]nonane-6-carboxylate chemical structure, C13H24N2O2, CAS 1363381-69-4](/s/VQHYDOIBWWTTKP-UHFFFAOYSA-N.svg)
tert-Butyl 2-amino-6-azaspiro[3.5]nonane-6-carboxylate
CAS 1363381-69-4C13H24N2O2
6-Boc-2-hydroxy-6-azaspiro(3.5)nonane
CAS 1419101-54-4C13H23NO3
9-Methyl-6-azaspiro(3.5)nonane
CAS 1427379-10-9C9H17N
![tert-Butyl 1-amino-6-azaspiro[3.5]nonane-6-carboxylate chemical structure, C13H24N2O2, CAS 1363381-72-9](/s/UQJBLNIEPDTKAQ-UHFFFAOYSA-N.svg)
tert-Butyl 1-amino-6-azaspiro[3.5]nonane-6-carboxylate
CAS 1363381-72-9C13H24N2O2
tert-Butyl 9-amino-6-azaspiro(3.5)nonane-6-carboxylate
CAS 1369143-47-4C13H24N2O2
![tert-Butyl N-{6-azaspiro[3.5]nonan-9-yl}carbamate chemical structure, C13H24N2O2, CAS 1369342-39-1](/s/AHIGUTRJWDFHRW-UHFFFAOYSA-N.svg)
tert-Butyl N-{6-azaspiro[3.5]nonan-9-yl}carbamate
CAS 1369342-39-1C13H24N2O2
6-Azaspiro(3.5)nonan-9-ol
CAS 1369246-31-0C8H15NO
![6-Azaspiro[3.5]nonane-2-carboxylic acid chemical structure, C9H15NO2, CAS 1500048-45-2](/s/OEYFDVMIJOOQND-UHFFFAOYSA-N.svg)
6-Azaspiro[3.5]nonane-2-carboxylic acid
CAS 1500048-45-2C9H15NO2
![6-[(tert-Butoxy)carbonyl]-6-azaspiro[3.5]nonane-9-carboxylic acid chemical structure, C14H23NO4, CAS 1782350-37-1](/s/FSPAGPQVXBYAFK-UHFFFAOYSA-N.svg)
6-[(tert-Butoxy)carbonyl]-6-azaspiro[3.5]nonane-9-carboxylic acid
CAS 1782350-37-1C14H23NO4
![(6-Azaspiro[3.5]nonan-2-yl)methanol chemical structure, C9H17NO, CAS 1784056-97-8](/s/BXFPPVOUVAOGHY-UHFFFAOYSA-N.svg)
(6-Azaspiro[3.5]nonan-2-yl)methanol
CAS 1784056-97-8C9H17NO
![Methyl 6-azaspiro[3.5]nonane-2-carboxylate chemical structure, C10H17NO2, CAS 1784137-04-7](/s/GYUAQQDCLHXVSC-UHFFFAOYSA-N.svg)
Methyl 6-azaspiro[3.5]nonane-2-carboxylate
CAS 1784137-04-7C10H17NO2
![tert-Butyl 2-((methylsulfonyl)oxy)-6-azaspiro[3.5]nonane-6-carboxylate chemical structure, C14H25NO5S, CAS 1421270-81-6](/s/ZTWHBUUEEANJSK-UHFFFAOYSA-N.svg)
tert-Butyl 2-((methylsulfonyl)oxy)-6-azaspiro[3.5]nonane-6-carboxylate
CAS 1421270-81-6C14H25NO5S
![2-Methyl-6-azaspiro[3.5]nonane chemical structure, C9H17N, CAS 1694667-48-5](/s/GSJKPKGBSOGXEV-UHFFFAOYSA-N.svg)
2-Methyl-6-azaspiro[3.5]nonane
CAS 1694667-48-5C9H17N
![tert-Butyl (1S,4R)-1-amino-6-azaspiro[3.5]nonane-6-carboxylate chemical structure, C13H24N2O2, CAS 1627972-88-6](/s/UQJBLNIEPDTKAQ-GXFFZTMASA-N.svg)
tert-Butyl (1S,4R)-1-amino-6-azaspiro[3.5]nonane-6-carboxylate
CAS 1627972-88-6C13H24N2O2
![tert-Butyl (1R,4R)-1-amino-6-azaspiro[3.5]nonane-6-carboxylate chemical structure, C13H24N2O2, CAS 1627972-89-7](/s/UQJBLNIEPDTKAQ-ZWNOBZJWSA-N.svg)
tert-Butyl (1R,4R)-1-amino-6-azaspiro[3.5]nonane-6-carboxylate
CAS 1627972-89-7C13H24N2O2
![2-Methoxy-6-azaspiro[3.5]nonane chemical structure, C9H17NO, CAS 1692760-05-6](/s/QLSXLLYFWSIARJ-UHFFFAOYSA-N.svg)
2-Methoxy-6-azaspiro[3.5]nonane
CAS 1692760-05-6C9H17NO
![9-(Trifluoromethyl)-6-azaspiro[3.5]nonane chemical structure, C9H14F3N, CAS 1803582-16-2](/s/DBAQCURGWZIETB-UHFFFAOYSA-N.svg)
9-(Trifluoromethyl)-6-azaspiro[3.5]nonane
CAS 1803582-16-2C9H14F3N
- 5-Methyl-6-azaspiro(3.5)nonane2243503-58-2C9H17N
- 7-Methyl-6-azaspiro[3.5]nonane1823914-27-7C9H17N
- tert-Butyl 2-(aminomethyl)-6-azaspiro[3.5]nonane-6-carboxylate1440961-44-3C14H26N2O2
- 1,1-Difluoro-6-azaspiro[3.5]nonane hydrochloride2097955-89-8C8H14ClF2N
- 1,1-Difluoro-6-azaspiro[3.5]nonane2091139-94-3C8H13F2N
- 6-((tert-Butoxy)carbonyl)-6-azaspiro(3.5)nonane-8-carboxylic acid1983309-33-6C14H23NO4
- 8-Methyl-6-azaspiro[3.5]nonane1823878-67-6C9H17N
- tert-Butyl 1-hydroxy-6-azaspiro[3.5]nonane-6-carboxylate1823805-67-9C13H23NO3
- tert-Butyl N-(6-azaspiro[3.5]nonan-3-yl)carbamate1935246-45-9C13H24N2O2
- 6-(tert-Butoxycarbonyl)-6-azaspiro[3.5]nonane-1-carboxylic acid2199106-84-6C14H23NO4
- tert-Butyl 2,2-difluoro-6-azaspiro[3.5]nonane-6-carboxylate1935419-86-5C13H21F2NO2
- 6-Azaspiro[3.5]nonane-6-carboxylic acid, 2-fluoro-, 1,1-dimethylethyl ester1936140-69-0C13H22FNO2
- tert-Butyl N-{6-azaspiro[3.5]nonan-2-yl}carbamate1440960-75-7C13H24N2O2
- tert-Butyl 2-formyl-6-azaspiro[3.5]nonane-6-carboxylate1440962-15-1C14H23NO3
- tert-Butyl ((6-azaspiro[3.5]nonan-2-yl)methyl)carbamate1440961-64-7C14H26N2O2
- 1-Methyl-6-azaspiro[3.5]nonane1849241-67-3C9H17N
- 6-(But-3-yn-1-yl)-6-azaspiro(3.5)nonane1856854-20-0C12H19N
- 6-Azaspiro[3.5]nonan-1-ol1823916-43-3C8H15NO
- 6-Azaspiro(3.5)nonan-8-ol2092805-31-5C8H15NO
- tert-Butyl 8-amino-6-azaspiro(3.5)nonane-6-carboxylate2091625-52-2C13H24N2O2
- 6-Azaspiro[3.5]nonane-2-carbonitrile2090129-48-7C9H14N2
- Ethyl 6-azaspiro[3.5]nonane-2-carboxylate2091127-61-4C11H19NO2
- 1-[9-(Trifluoromethyl)-6-azaspiro[3.5]nonan-6-yl]prop-2-en-1-one2191110-26-4C12H16F3NO
- 2-Methoxy-6-azaspiro[3.5]nonane hydrochloride2306272-18-2C9H18ClNO
Related scaffolds
Same ring framework with different atoms or bond orders
C1CC2(C1)CCNCC241 chemicals
C1CCC2(CC1)CCC238 chemicals
C1CC2(C1)CCOCC229 chemicals
C1CCC2(CCC2)OC126 chemicals
C1CC2(C1)CNCCO219 chemicals
C1CC2(CCN1)CNC215 chemicals
C1CCC2(CC1)CNC214 chemicals
C1CCC2(CCC2)NC114 chemicals
C1CCC2(CC1)CCN212 chemicals
C1COCC2(C1)CCC210 chemicals
C1CC2(C1)COCCN210 chemicals
C1CC2(CCO1)CNC210 chemicals