Murcko scaffold
8-Oxa-5-azaspiro[3.5]nonane scaffold
62 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 9
- Chemicals
- 62
- With full pages
- 10
Scaffold SMILES
C1CC2(C1)COCCN2
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 62 chemicals
![8-Oxa-5-azaspiro[3.5]nonane chemical structure, C7H13NO, CAS 602326-48-7](/s/QJWGZYJFBDSKHF-UHFFFAOYSA-N.svg)
8-Oxa-5-azaspiro[3.5]nonane
CAS 602326-48-7C7H13NO
![5-(tert-Butoxycarbonyl)-8-oxa-5-azaspiro[3.5]nonane-2-carboxylic acid chemical structure, C13H21NO5, CAS 1251022-92-0](/s/RFSTURQDTDVQDU-UHFFFAOYSA-N.svg)
5-(tert-Butoxycarbonyl)-8-oxa-5-azaspiro[3.5]nonane-2-carboxylic acid
CAS 1251022-92-0C13H21NO5
![tert-Butyl 2-amino-8-oxa-5-azaspiro[3.5]nonane-5-carboxylate chemical structure, C12H22N2O3, CAS 1251019-55-2](/s/RUNXLCYDBFRQDH-UHFFFAOYSA-N.svg)
tert-Butyl 2-amino-8-oxa-5-azaspiro[3.5]nonane-5-carboxylate
CAS 1251019-55-2C12H22N2O3
![8-Oxa-5-azaspiro[3.5]nonane hydrochloride chemical structure, C7H14ClNO, CAS 1147107-82-1](/s/CPDIUQLSJNMUMM-UHFFFAOYSA-N.svg)
8-Oxa-5-azaspiro[3.5]nonane hydrochloride
CAS 1147107-82-1C7H14ClNO
![8-Oxa-5-azaspiro[3.5]nonane oxalate chemical structure, C9H15NO5, CAS 1980053-02-8](/s/VMOOTGBWCBNDMK-UHFFFAOYSA-N.svg)
8-Oxa-5-azaspiro[3.5]nonane oxalate
CAS 1980053-02-8C9H15NO5
![8-Oxa-5-azaspiro[3.5]nonane hemioxalate chemical structure, C16H28N2O6, CAS 1523571-09-6](/s/PCPDSHLMSFXNEY-UHFFFAOYSA-N.svg)
8-Oxa-5-azaspiro[3.5]nonane hemioxalate
CAS 1523571-09-6C16H28N2O6
![(2S,4s,7R)-7-Methyl-8-oxa-5-azaspiro[3.5]nonan-2-ol hydrochloride chemical structure, C8H16ClNO2, CAS 1639988-83-2](/s/SJGNQYLKRPJXNE-PUFYQOQHSA-N.svg)
(2S,4s,7R)-7-Methyl-8-oxa-5-azaspiro[3.5]nonan-2-ol hydrochloride
CAS 1639988-83-2C8H16ClNO2
![(2S,4s,7R)-7-Methyl-8-oxa-5-azaspiro[3.5]nonan-2-ol chemical structure, C8H15NO2, CAS 1640033-15-3](/s/GEKPVRAFWVXKPO-JECWYVHBSA-N.svg)
(2S,4s,7R)-7-Methyl-8-oxa-5-azaspiro[3.5]nonan-2-ol
CAS 1640033-15-3C8H15NO2
![7-Methyl-8-oxa-5-azaspiro[3.5]nonane chemical structure, C8H15NO, CAS 1955540-56-3](/s/PKOSNXIRJSEGDW-UHFFFAOYSA-N.svg)
7-Methyl-8-oxa-5-azaspiro[3.5]nonane
CAS 1955540-56-3C8H15NO
![N-{[6-(Hydroxymethyl)-5-methyl-8-oxa-5-azaspiro[3.5]nonan-6-yl]methyl}prop-2-enamide chemical structure, C13H22N2O3, CAS 2094270-50-3](/s/DWSDNSKGDLOSBZ-UHFFFAOYSA-N.svg)
N-{[6-(Hydroxymethyl)-5-methyl-8-oxa-5-azaspiro[3.5]nonan-6-yl]methyl}prop-2-enamide
CAS 2094270-50-3C13H22N2O3
![2-{8-Oxa-5-azaspiro[3.5]nonan-5-yl}ethan-1-amine chemical structure, C9H18N2O, CAS 1864728-10-8](/s/LLHSNJKRMWZJFB-UHFFFAOYSA-N.svg)
2-{8-Oxa-5-azaspiro[3.5]nonan-5-yl}ethan-1-amine
CAS 1864728-10-8C9H18N2O
![2,2-Dimethyl-8-oxa-5-azaspiro[3.5]nonane chemical structure, C9H17NO, CAS 1935953-52-8](/s/HQWJPRCRPGOHAN-UHFFFAOYSA-N.svg)
2,2-Dimethyl-8-oxa-5-azaspiro[3.5]nonane
CAS 1935953-52-8C9H17NO
![[6-(Aminomethyl)-5-methyl-8-oxa-5-azaspiro[3.5]nonan-6-yl]methanol chemical structure, C10H20N2O2, CAS 2044797-00-2](/s/SWEIMHIYBRCHBV-UHFFFAOYSA-N.svg)
[6-(Aminomethyl)-5-methyl-8-oxa-5-azaspiro[3.5]nonan-6-yl]methanol
CAS 2044797-00-2C10H20N2O2
![Methyl 2-(8-oxa-5-azaspiro[3.5]nonan-7-yl)acetate, hydrochloride chemical structure, C10H18ClNO3, CAS 2248388-79-4](/s/PMFCNFZCPWZFKA-UHFFFAOYSA-N.svg)
Methyl 2-(8-oxa-5-azaspiro[3.5]nonan-7-yl)acetate, hydrochloride
CAS 2248388-79-4C10H18ClNO3
![Methyl 2-{8-oxa-5-azaspiro[3.5]nonan-7-yl}acetate chemical structure, C10H17NO3, CAS 2167390-02-3](/s/JQKTYCKEBKHKSJ-UHFFFAOYSA-N.svg)
Methyl 2-{8-oxa-5-azaspiro[3.5]nonan-7-yl}acetate
CAS 2167390-02-3C10H17NO3
![2-{8-Oxa-5-azaspiro[3.5]nonan-7-yl}acetic acid hydrochloride chemical structure, C9H16ClNO3, CAS 2248352-24-9](/s/WGKQKDSCURFOPX-UHFFFAOYSA-N.svg)
2-{8-Oxa-5-azaspiro[3.5]nonan-7-yl}acetic acid hydrochloride
CAS 2248352-24-9C9H16ClNO3
![2-{8-Oxa-5-azaspiro[3.5]nonan-7-yl}acetic acid chemical structure, C9H15NO3, CAS 2168195-78-4](/s/XCQJLWKRSZNGJH-UHFFFAOYSA-N.svg)
2-{8-Oxa-5-azaspiro[3.5]nonan-7-yl}acetic acid
CAS 2168195-78-4C9H15NO3
![2-{5-[(tert-Butoxy)carbonyl]-8-oxa-5-azaspiro[3.5]nonan-7-yl}acetic acid chemical structure, C14H23NO5, CAS 2248286-87-3](/s/YMGLFLBAMSWJQP-UHFFFAOYSA-N.svg)
2-{5-[(tert-Butoxy)carbonyl]-8-oxa-5-azaspiro[3.5]nonan-7-yl}acetic acid
CAS 2248286-87-3C14H23NO5
![tert-Butyl 7-(aminomethyl)-8-oxa-5-azaspiro[3.5]nonane-5-carboxylate chemical structure, C13H24N2O3, CAS 2167527-68-4](/s/SJFJVJJMNZWYBV-UHFFFAOYSA-N.svg)
tert-Butyl 7-(aminomethyl)-8-oxa-5-azaspiro[3.5]nonane-5-carboxylate
CAS 2167527-68-4C13H24N2O3
5-((tert-Butoxy)carbonyl)-8-oxa-5-azaspiro(3.5)nonane-7-carboxylic acid
CAS 2287310-69-2C13H21NO5
![tert-Butyl 2-{8-oxa-5-azaspiro[3.5]nonan-7-yl}acetate chemical structure, C13H23NO3, CAS 2287298-03-5](/s/QFFYGKOSLUFIIC-UHFFFAOYSA-N.svg)
tert-Butyl 2-{8-oxa-5-azaspiro[3.5]nonan-7-yl}acetate
CAS 2287298-03-5C13H23NO3
![8-Oxa-5-azaspiro[3.5]nonane-7-carboxylic acid hydrochloride chemical structure, C8H14ClNO3, CAS 2287283-69-4](/s/KNQPLGCHMAQTSY-UHFFFAOYSA-N.svg)
8-Oxa-5-azaspiro[3.5]nonane-7-carboxylic acid hydrochloride
CAS 2287283-69-4C8H14ClNO3
![8-Oxa-5-azaspiro[3.5]nonane-7-carboxylic acid chemical structure, C8H13NO3, CAS 2167698-86-2](/s/LKCQDLUAZJRZLU-UHFFFAOYSA-N.svg)
8-Oxa-5-azaspiro[3.5]nonane-7-carboxylic acid
CAS 2167698-86-2C8H13NO3
Methyl 8-oxa-5-azaspiro(3.5)nonane-7-carboxylate
CAS 2287332-53-8C9H15NO3
- (8-Oxa-5-azaspiro(3.5)nonan-7-yl)methanol hydrochloride2287313-40-8C8H16ClNO2
- {8-Oxa-5-azaspiro[3.5]nonan-7-yl}methanol2287313-39-5C8H15NO2
- Ethyl 2-{8-oxa-5-azaspiro[3.5]nonan-7-yl}acetate2287340-55-8C11H19NO3
- tert-Butyl 7-(iodomethyl)-8-oxa-5-azaspiro[3.5]nonane-5-carboxylate2169497-71-4C13H22INO3
- 2-(5-Prop-2-enoyl-8-oxa-5-azaspiro[3.5]nonan-7-yl)acetic acid2305568-49-2C12H17NO4
- 5-[2-(Ethenesulfonyl)ethyl]-7-methyl-8-oxa-5-azaspiro[3.5]nonane2305454-69-5C12H21NO3S
- 2-Chloro-N-[[6-(hydroxymethyl)-5-methyl-8-oxa-5-azaspiro[3.5]nonan-6-yl]methyl]propanamide2411249-65-3C13H23ClN2O3
- (2E)-4-(Dimethylamino)-N-{[6-(hydroxymethyl)-5-methyl-8-oxa-5-azaspiro[3.5]nonan-6-yl]methyl}but-2-enamide2411327-48-3C16H29N3O3
- tert-Butyl 7-(hydroxymethyl)-8-oxa-5-azaspiro[3.5]nonane-5-carboxylate2413896-19-0C13H23NO4
- (2s,4s)-2-Methoxy-2-(trifluoromethyl)-8-oxa-5-azaspiro[3.5]nonane hydrochloride2613384-82-8C9H15ClF3NO2
- (2s,4s)-2-Methoxy-2-(trifluoromethyl)-8-oxa-5-azaspiro[3.5]nonane2613381-96-5C9H14F3NO2
- 2,2,2-Trifluoro-1-{8-oxa-5-azaspiro[3.5]nonan-5-yl}ethan-1-one2274275-70-4C9H12F3NO2
- tert-Butyl 8-oxa-5-azaspiro[3.5]nonane-5-carboxylate2149514-52-1C12H21NO3
- tert-Butyl N-{[6-(hydroxymethyl)-5-methyl-8-oxa-5-azaspiro[3.5]nonan-6-yl]methyl}carbamate2408962-60-5C15H28N2O4
- N-{[6-(Hydroxymethyl)-5-methyl-8-oxa-5-azaspiro[3.5]nonan-6-yl]methyl}but-2-ynamide2411291-26-2C14H22N2O3
- 2-Chloro-N-{[6-(hydroxymethyl)-5-methyl-8-oxa-5-azaspiro[3.5]nonan-6-yl]methyl}acetamide2411278-85-6C12H21ClN2O3
- (2s,4s)-2-(Trifluoromethyl)-8-oxa-5-azaspiro[3.5]nonan-2-ol2503204-48-4C8H12F3NO2
- (2s,4s)-2-(Trifluoromethyl)-8-oxa-5-azaspiro[3.5]nonan-2-ol hydrochloride2503208-74-8C8H13ClF3NO2
- tert-Butyl (2s,4s)-2-hydroxy-2-(trifluoromethyl)-8-oxa-5-azaspiro[3.5]nonane-5-carboxylate2580184-88-7C13H20F3NO4
- tert-Butyl 8-oxa-5-azaspiro[3.5]nonane-7-carboxylate2580228-95-9C12H21NO3
- Ethyl 8-oxa-5-azaspiro[3.5]nonane-7-carboxylate2580198-58-7C10H17NO3
- 5-Nitroso-8-oxa-5-azaspiro[3.5]nonane-7-carboxylic acid2624140-97-0C8H12N2O4
- 2-{5-Nitroso-8-oxa-5-azaspiro[3.5]nonan-7-yl}acetic acid2624137-43-3C9H14N2O4
- 2-{5-[(Prop-2-en-1-yloxy)carbonyl]-8-oxa-5-azaspiro[3.5]nonan-7-yl}acetic acid2680723-99-1C13H19NO5
Related scaffolds
Same ring framework with different atoms or bond orders
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