CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 22 atoms

376 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
376
With full pages
5
Scaffold SMILES

O=C(Nc1ccccc1)C1=CNC(=S)NC1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)C1=CNC(=S)NC1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 96 of 376 chemicals

N-(4-Chlorophenyl)-4-(4-(dimethylamino)phenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide chemical structure, C20H21ClN4OS, CAS 313392-21-1
N-(4-Chlorophenyl)-4-(4-(dimethylamino)phenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide
CAS 313392-21-1C20H21ClN4OS
N-(4-Chlorophenyl)-4-(3,4-dimethoxyphenyl)-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxamide chemical structure, C20H20ClN3O3S, CAS 328557-06-8
N-(4-Chlorophenyl)-4-(3,4-dimethoxyphenyl)-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxamide
CAS 328557-06-8C20H20ClN3O3S
4-(3-Bromophenyl)-N-(4-chlorophenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxamide chemical structure, C18H15BrClN3OS, CAS 328557-04-6
4-(3-Bromophenyl)-N-(4-chlorophenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxamide
CAS 328557-04-6C18H15BrClN3OS
N-(4-Chlorophenyl)-6-methyl-2-sulfanylidene-4-(3,4,5-trimethoxyphenyl)-3,4-dihydro-1H-pyrimidine-5-carboxamide chemical structure, C21H22ClN3O4S, CAS 312735-19-6
N-(4-Chlorophenyl)-6-methyl-2-sulfanylidene-4-(3,4,5-trimethoxyphenyl)-3,4-dihydro-1H-pyrimidine-5-carboxamide
CAS 312735-19-6C21H22ClN3O4S
N-(4-Chlorophenyl)-6-methyl-2-sulfanylidene-4-(2,4,5-trimethoxyphenyl)-3,4-dihydro-1H-pyrimidine-5-carboxamide chemical structure, C21H22ClN3O4S, CAS 330453-66-2
N-(4-Chlorophenyl)-6-methyl-2-sulfanylidene-4-(2,4,5-trimethoxyphenyl)-3,4-dihydro-1H-pyrimidine-5-carboxamide
CAS 330453-66-2C21H22ClN3O4S
6-(2,5-Dimethoxyphenyl)-4-methyl-N-phenyl-2-sulfanyl-1,6-dihydropyrimidine-5-carboxamide chemical structure, C20H21N3O3S, CAS 312621-07-1
6-(2,5-Dimethoxyphenyl)-4-methyl-N-phenyl-2-sulfanyl-1,6-dihydropyrimidine-5-carboxamide
CAS 312621-07-1C20H21N3O3S
4-(4-Bromophenyl)-N-(4-ethoxyphenyl)-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxamide chemical structure, C20H20BrN3O2S, CAS 333767-33-2
4-(4-Bromophenyl)-N-(4-ethoxyphenyl)-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxamide
CAS 333767-33-2C20H20BrN3O2S
4-(2,5-Dimethoxyphenyl)-N-(4-methoxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide chemical structure, C21H23N3O4S, CAS 333767-78-5
4-(2,5-Dimethoxyphenyl)-N-(4-methoxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide
CAS 333767-78-5C21H23N3O4S
N-(4-Bromophenyl)-4-(4-fluorophenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide chemical structure, C18H15BrFN3OS, CAS 333768-13-1
N-(4-Bromophenyl)-4-(4-fluorophenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide
CAS 333768-13-1C18H15BrFN3OS
4-(3-Bromophenyl)-N-(4-methoxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide chemical structure, C19H18BrN3O2S, CAS 333767-71-8
4-(3-Bromophenyl)-N-(4-methoxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide
CAS 333767-71-8C19H18BrN3O2S
4-(4-Chlorophenyl)-N-(4-methoxyphenyl)-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxamide chemical structure, C19H18ClN3O2S, CAS 333767-80-9
4-(4-Chlorophenyl)-N-(4-methoxyphenyl)-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxamide
CAS 333767-80-9C19H18ClN3O2S
4-(2-Bromophenyl)-N-(4-methoxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide chemical structure, C19H18BrN3O2S, CAS 5745-68-6
4-(2-Bromophenyl)-N-(4-methoxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide
CAS 5745-68-6C19H18BrN3O2S
N-(4-Methoxyphenyl)-6-methyl-4-phenyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide chemical structure, C19H19N3O2S, CAS 333767-83-2
N-(4-Methoxyphenyl)-6-methyl-4-phenyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide
CAS 333767-83-2C19H19N3O2S
N-(4-Ethoxyphenyl)-6-methyl-4-(4-methylphenyl)-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxamide chemical structure, C21H23N3O2S, CAS 333767-21-8
N-(4-Ethoxyphenyl)-6-methyl-4-(4-methylphenyl)-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxamide
CAS 333767-21-8C21H23N3O2S
4-[4-(Dimethylamino)phenyl]-N-(4-methoxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxamide chemical structure, C21H24N4O2S, CAS 333767-58-1
4-[4-(Dimethylamino)phenyl]-N-(4-methoxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxamide
CAS 333767-58-1C21H24N4O2S
6-Methyl-N,4-bis(4-methylphenyl)-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide chemical structure, C20H21N3OS, CAS 333767-96-7
6-Methyl-N,4-bis(4-methylphenyl)-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide
CAS 333767-96-7C20H21N3OS
4-(3,4-Dimethoxyphenyl)-N-(4-ethoxyphenyl)-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxamide chemical structure, C22H25N3O4S, CAS 380644-45-1
4-(3,4-Dimethoxyphenyl)-N-(4-ethoxyphenyl)-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxamide
CAS 380644-45-1C22H25N3O4S
4-(3-Ethoxy-4-hydroxyphenyl)-6-methyl-N-(2-methylphenyl)-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxamide chemical structure, C21H23N3O3S, CAS 333768-39-1
4-(3-Ethoxy-4-hydroxyphenyl)-6-methyl-N-(2-methylphenyl)-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxamide
CAS 333768-39-1C21H23N3O3S
4-(2-Fluorophenyl)-6-methyl-N-(4-methylphenyl)-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxamide chemical structure, C19H18FN3OS, CAS 333768-26-6
4-(2-Fluorophenyl)-6-methyl-N-(4-methylphenyl)-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxamide
CAS 333768-26-6C19H18FN3OS
4-(4-Hydroxyphenyl)-N-(4-methoxyphenyl)-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxamide chemical structure, C19H19N3O3S, CAS 333767-55-8
4-(4-Hydroxyphenyl)-N-(4-methoxyphenyl)-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxamide
CAS 333767-55-8C19H19N3O3S
N-(4-Methoxyphenyl)-6-methyl-2-sulfanylidene-4-(2,4,5-trimethoxyphenyl)-1,2,3,4-tetrahydropyrimidine-5-carboxamide chemical structure, C22H25N3O5S, CAS 5755-62-4
N-(4-Methoxyphenyl)-6-methyl-2-sulfanylidene-4-(2,4,5-trimethoxyphenyl)-1,2,3,4-tetrahydropyrimidine-5-carboxamide
CAS 5755-62-4C22H25N3O5S
N-(4-Bromophenyl)-4-(2-fluorophenyl)-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxamide chemical structure, C18H15BrFN3OS, CAS 5755-78-2
N-(4-Bromophenyl)-4-(2-fluorophenyl)-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxamide
CAS 5755-78-2C18H15BrFN3OS
N-(4-Ethoxyphenyl)-4-(4-methoxyphenyl)-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxamide chemical structure, C21H23N3O3S, CAS 333767-19-4
N-(4-Ethoxyphenyl)-4-(4-methoxyphenyl)-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxamide
CAS 333767-19-4C21H23N3O3S
4-(3-Ethoxy-4-hydroxyphenyl)-N-(4-methoxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide chemical structure, C21H23N3O4S, CAS 5757-04-0
4-(3-Ethoxy-4-hydroxyphenyl)-N-(4-methoxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide
CAS 5757-04-0C21H23N3O4S