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Murcko scaffold

Ring system with 3 rings and 13 atoms

31 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
13
Chemicals
31
With full pages
8
Scaffold SMILES

c1ccc2c(c1)CCc1ccsc1-2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc2c(c1)CCc1ccsc1-2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 31 of 31 chemicals

Ethyl 4,5-dihydronaphtho[1,2-b]thiophene-2-carboxylate chemical structure, C15H14O2S, CAS 19397-74-1
Ethyl 4,5-dihydronaphtho[1,2-b]thiophene-2-carboxylate
CAS 19397-74-1C15H14O2S
4H,5H-Naphtho(1,2-b)thiophene-2-carboxylic acid chemical structure, C13H10O2S, CAS 29179-41-7
4H,5H-Naphtho(1,2-b)thiophene-2-carboxylic acid
CAS 29179-41-7C13H10O2S
Ethyl 2-acetamido-4,5-dihydrobenzo[g][1]benzothiole-3-carboxylate chemical structure, C17H17NO3S, CAS 375835-85-1
Ethyl 2-acetamido-4,5-dihydrobenzo[g][1]benzothiole-3-carboxylate
CAS 375835-85-1C17H17NO3S
Ethyl 2-amino-4,5-dihydronaphtho[1,2-b]thiophene-3-carboxylate chemical structure, C15H15NO2S, CAS 332159-69-0
Ethyl 2-amino-4,5-dihydronaphtho[1,2-b]thiophene-3-carboxylate
CAS 332159-69-0C15H15NO2S
Methyl 2-amino-4,5-dihydronaphtho[1,2-b]thiophene-3-carboxylate chemical structure, C14H13NO2S, CAS 350999-16-5
Methyl 2-amino-4,5-dihydronaphtho[1,2-b]thiophene-3-carboxylate
CAS 350999-16-5C14H13NO2S
2-(Acetylamino)-4,5-dihydronaphtho[1,2-b]thiophene-3-carboxylic acid chemical structure, C15H13NO3S, CAS 433688-29-0
2-(Acetylamino)-4,5-dihydronaphtho[1,2-b]thiophene-3-carboxylic acid
CAS 433688-29-0C15H13NO3S
Ethyl 2-(butanoylamino)-4,5-dihydrobenzo[g][1]benzothiole-3-carboxylate chemical structure, C19H21NO3S, CAS 487023-09-6
Ethyl 2-(butanoylamino)-4,5-dihydrobenzo[g][1]benzothiole-3-carboxylate
CAS 487023-09-6C19H21NO3S
Ethyl 2-[(chloroacetyl)amino]-4,5-dihydronaphtho[1,2-b]thiophene-3-carboxylate chemical structure, C17H16ClNO3S, CAS 497230-86-1
Ethyl 2-[(chloroacetyl)amino]-4,5-dihydronaphtho[1,2-b]thiophene-3-carboxylate
CAS 497230-86-1C17H16ClNO3S
Methyl (3-carbamoyl-4,5-dihydronaphtho[1,2-b]thiophen-2-yl)carbamate chemical structure, C15H14N2O3S, CAS 717866-59-6
Methyl (3-carbamoyl-4,5-dihydronaphtho[1,2-b]thiophen-2-yl)carbamate
CAS 717866-59-6C15H14N2O3S
N-Methyl-4,5-dihydronaphtho[1,2-b]thiophene-2-carboxamide chemical structure, C14H13NOS, CAS 320424-03-1
N-Methyl-4,5-dihydronaphtho[1,2-b]thiophene-2-carboxamide
CAS 320424-03-1C14H13NOS
N,N-Dimethyl-4,5-dihydronaphtho[1,2-b]thiophene-2-carboxamide chemical structure, C15H15NOS, CAS 320424-04-2
N,N-Dimethyl-4,5-dihydronaphtho[1,2-b]thiophene-2-carboxamide
CAS 320424-04-2C15H15NOS
Methyl 3-amino-4,5-dihydronaphtho[1,2-b]thiophene-2-carboxylate chemical structure, C14H13NO2S, CAS 691393-99-4
Methyl 3-amino-4,5-dihydronaphtho[1,2-b]thiophene-2-carboxylate
CAS 691393-99-4C14H13NO2S
Methyl 4,5-dihydronaphtho[1,2-b]thiophene-2-carboxylate chemical structure, C14H12O2S, CAS 320423-96-9
Methyl 4,5-dihydronaphtho[1,2-b]thiophene-2-carboxylate
CAS 320423-96-9C14H12O2S
2-Amino-4,5-dihydronaphtho[1,2-b]thiophene-3-carbonitrile chemical structure, C13H10N2S, CAS 13145-86-3
2-Amino-4,5-dihydronaphtho[1,2-b]thiophene-3-carbonitrile
CAS 13145-86-3C13H10N2S
4,5-Dihydronaphtho[1,2-b]thiophene-2-carbohydrazide chemical structure, C13H12N2OS, CAS 278782-13-1
4,5-Dihydronaphtho[1,2-b]thiophene-2-carbohydrazide
CAS 278782-13-1C13H12N2OS
N'-(4,5-Dihydronaphtho[1,2-b]thiophen-2-ylcarbonyl)methanesulfonohydrazide chemical structure, C14H14N2O3S2, CAS 478033-49-7
N'-(4,5-Dihydronaphtho[1,2-b]thiophen-2-ylcarbonyl)methanesulfonohydrazide
CAS 478033-49-7C14H14N2O3S2
7-Methoxy-4H,5H-naphtho[1,2-b]thiophene-2-carboxylic acid chemical structure, C14H12O3S, CAS 78554-65-1
7-Methoxy-4H,5H-naphtho[1,2-b]thiophene-2-carboxylic acid
CAS 78554-65-1C14H12O3S
2-Amino-4,5-dihydronaphtho[1,2-b]thiophene-3-carboxamide chemical structure, C13H12N2OS, CAS 617688-39-8
2-Amino-4,5-dihydronaphtho[1,2-b]thiophene-3-carboxamide
CAS 617688-39-8C13H12N2OS
Ethanone, 1-(4,5-dihydro-8-methylnaphtho[1,2-b]thien-2-yl)- chemical structure, C15H14OS, CAS 837372-02-8
Ethanone, 1-(4,5-dihydro-8-methylnaphtho[1,2-b]thien-2-yl)-
CAS 837372-02-8C15H14OS
2-Bromo-4,5-dihydronaphtho[1,2-b]thiophene chemical structure, C12H9BrS, CAS 62615-56-9
2-Bromo-4,5-dihydronaphtho[1,2-b]thiophene
CAS 62615-56-9C12H9BrS
4,5-Dihydronaphtho[1,2-b]thiophene-2-carbonitrile chemical structure, C13H9NS, CAS 62615-61-6
4,5-Dihydronaphtho[1,2-b]thiophene-2-carbonitrile
CAS 62615-61-6C13H9NS
1-(4,5-Dihydronaphtho[1,2-b]thiophen-2-yl)ethan-1-one chemical structure, C14H12OS, CAS 62615-59-2
1-(4,5-Dihydronaphtho[1,2-b]thiophen-2-yl)ethan-1-one
CAS 62615-59-2C14H12OS
1,1'-(4,5-Dihydronaphtho[1,2-b]thiene-2,7-diyl)di(ethan-1-one) chemical structure, C16H14O2S, CAS 62615-48-9
1,1'-(4,5-Dihydronaphtho[1,2-b]thiene-2,7-diyl)di(ethan-1-one)
CAS 62615-48-9C16H14O2S
[(1-Cyano-1,2-dimethylpropyl)carbamoyl]methyl 4H,5H-naphtho[1,2-B]thiophene-2-carboxylate chemical structure, C21H22N2O3S, CAS 878079-00-6
[(1-Cyano-1,2-dimethylpropyl)carbamoyl]methyl 4H,5H-naphtho[1,2-B]thiophene-2-carboxylate
CAS 878079-00-6C21H22N2O3S