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Murcko scaffold

N-Phenyl-4-(pyridin-3-yl)pyrimidin-2-amine scaffold

43 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
43
With full pages
4
Scaffold SMILES

c1ccc(Nc2nccc(-c3cccnc3)n2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-Phenyl-4-(pyridin-3-yl)pyrimidin-2-amine page
Murcko scaffold c1ccc(Nc2nccc(-c3cccnc3)n2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 43 of 43 chemicals

Imatinib amine chemical structure, C16H15N5, CAS 152460-10-1
Imatinib amine
CAS 152460-10-1C16H15N5
3-[[4-(3-Pyridinyl)-2-pyrimidinyl]amino]benzoic acid chemical structure, C16H12N4O2, CAS 188260-51-7
3-[[4-(3-Pyridinyl)-2-pyrimidinyl]amino]benzoic acid
CAS 188260-51-7C16H12N4O2
4-Methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)benzoic acid chemical structure, C17H14N4O2, CAS 641569-94-0
4-Methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)benzoic acid
CAS 641569-94-0C17H14N4O2
2-(2-Methyl-5-nitroanilino)-4-(3-pyridyl)pyrimidine chemical structure, C16H13N5O2, CAS 152460-09-8
2-(2-Methyl-5-nitroanilino)-4-(3-pyridyl)pyrimidine
CAS 152460-09-8C16H13N5O2
4-(Pyridin-3-yl)-N-(o-tolyl)pyrimidin-2-amine chemical structure, C16H14N4, CAS 181065-56-5
4-(Pyridin-3-yl)-N-(o-tolyl)pyrimidin-2-amine
CAS 181065-56-5C16H14N4
N-(4-Nitrophenyl)-4-(3-pyridyl)-2-pyrimidineamine chemical structure, C15H11N5O2, CAS 181065-58-7
N-(4-Nitrophenyl)-4-(3-pyridyl)-2-pyrimidineamine
CAS 181065-58-7C15H11N5O2
4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzamide chemical structure, C17H15N5O, CAS 851137-91-2
4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzamide
CAS 851137-91-2C17H15N5O
N-Phenyl-4-(pyridin-3-yl)pyrimidin-2-amine chemical structure, C15H12N4, CAS 112675-73-7
N-Phenyl-4-(pyridin-3-yl)pyrimidin-2-amine
CAS 112675-73-7C15H12N4
3-[[4-(3-Pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester chemical structure, C17H14N4O2, CAS 156790-79-3
3-[[4-(3-Pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester
CAS 156790-79-3C17H14N4O2
2-Chloro-N-[4-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]acetamide chemical structure, C17H14ClN5O, CAS 881674-63-1
2-Chloro-N-[4-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]acetamide
CAS 881674-63-1C17H14ClN5O
N-(4-Methoxyphenyl)-4-(pyridin-3-yl)pyrimidin-2-amine chemical structure, C16H14N4O, CAS 112675-67-9
N-(4-Methoxyphenyl)-4-(pyridin-3-yl)pyrimidin-2-amine
CAS 112675-67-9C16H14N4O
Ethyl 3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)benzoate chemical structure, C18H16N4O2, CAS 112696-09-0
Ethyl 3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)benzoate
CAS 112696-09-0C18H16N4O2
N1-(4-(pyridin-3-yl)pyrimidin-2-yl)benzene-1,4-diamine chemical structure, C15H13N5, CAS 150784-74-0
N1-(4-(pyridin-3-yl)pyrimidin-2-yl)benzene-1,4-diamine
CAS 150784-74-0C15H13N5
N-(2-Chlorophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine chemical structure, C15H11ClN4, CAS 150784-71-7
N-(2-Chlorophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine
CAS 150784-71-7C15H11ClN4
Methyl 4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoate chemical structure, C18H16N4O2, CAS 917392-54-2
Methyl 4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoate
CAS 917392-54-2C18H16N4O2
3-((4-(Pyridin-3-yl)pyrimidin-2-yl)amino)benzamide chemical structure, C16H13N5O, CAS 919991-24-5
3-((4-(Pyridin-3-yl)pyrimidin-2-yl)amino)benzamide
CAS 919991-24-5C16H13N5O
4-(5-Bromopyridin-3-yl)-N-(2-methyl-5-nitrophenyl)pyrimidin-2-amine chemical structure, C16H12BrN5O2, CAS 641615-41-0
4-(5-Bromopyridin-3-yl)-N-(2-methyl-5-nitrophenyl)pyrimidin-2-amine
CAS 641615-41-0C16H12BrN5O2
3-[4-(5-Bromopyridin-3-yl)pyrimidin-2-ylamino]-4-methylaniline chemical structure, C16H14BrN5, CAS 641615-42-1
3-[4-(5-Bromopyridin-3-yl)pyrimidin-2-ylamino]-4-methylaniline
CAS 641615-42-1C16H14BrN5
N-(3-Amino-4-methylphenyl)-4-(pyridin-3-yl)-2-pyrimidine-amine chemical structure, C16H15N5, CAS 571187-03-6
N-(3-Amino-4-methylphenyl)-4-(pyridin-3-yl)-2-pyrimidine-amine
CAS 571187-03-6C16H15N5
4-Chloro-N-(2-methyl-5-nitrophenyl)-6-pyridin-3-ylpyrimidin-2-amine chemical structure, C16H12ClN5O2, CAS 1016637-24-3
4-Chloro-N-(2-methyl-5-nitrophenyl)-6-pyridin-3-ylpyrimidin-2-amine
CAS 1016637-24-3C16H12ClN5O2
(3-Chloro-phenyl)-[4-(2-chloro-pyridin-3-yl)-pyrimidin-2-yl]-amine chemical structure, C15H10Cl2N4, CAS 1035943-65-7
(3-Chloro-phenyl)-[4-(2-chloro-pyridin-3-yl)-pyrimidin-2-yl]-amine
CAS 1035943-65-7C15H10Cl2N4
N-(4-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine chemical structure, C16H15N5, CAS 112696-91-0
N-(4-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine
CAS 112696-91-0C16H15N5
N-(2-Methyl-5-nitrophenyl)-N-[4-pyridin-3-yl-pyrimidin-2-yl]-t-boc chemical structure, C21H21N5O4, CAS 1076198-55-4
N-(2-Methyl-5-nitrophenyl)-N-[4-pyridin-3-yl-pyrimidin-2-yl]-t-boc
CAS 1076198-55-4C21H21N5O4
Ethyl 4-methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)benzoate chemical structure, C19H18N4O2, CAS 641569-97-3
Ethyl 4-methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)benzoate
CAS 641569-97-3C19H18N4O2