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Murcko scaffold

Ring system with 3 rings and 19 atoms

46 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
46
With full pages
18
Scaffold SMILES

c1ccc(Oc2ccnc(-c3ccccc3)n2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Oc2ccnc(-c3ccccc3)n2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 46 of 46 chemicals

4-((2-(2-Hydroxyphenyl)-6-methylpyrimidin-4-yl)oxy)benzonitrile chemical structure, C18H13N3O2, CAS 380590-05-6
4-((2-(2-Hydroxyphenyl)-6-methylpyrimidin-4-yl)oxy)benzonitrile
CAS 380590-05-6C18H13N3O2
4-((Methylsulfanyl)methyl)-6-phenoxy-2-phenylpyrimidine chemical structure, C18H16N2OS, CAS 477886-19-4
4-((Methylsulfanyl)methyl)-6-phenoxy-2-phenylpyrimidine
CAS 477886-19-4C18H16N2OS
4-(2,3-Dimethylphenoxy)-5-methoxy-2-phenylpyrimidine chemical structure, C19H18N2O2, CAS 478029-61-7
4-(2,3-Dimethylphenoxy)-5-methoxy-2-phenylpyrimidine
CAS 478029-61-7C19H18N2O2
4-(4-tert-Butylphenoxy)-5-methoxy-2-phenylpyrimidine chemical structure, C21H22N2O2, CAS 861209-06-5
4-(4-tert-Butylphenoxy)-5-methoxy-2-phenylpyrimidine
CAS 861209-06-5C21H22N2O2
5-Methoxy-4-(2-methylphenoxy)-2-phenylpyrimidine chemical structure, C18H16N2O2, CAS 478029-67-3
5-Methoxy-4-(2-methylphenoxy)-2-phenylpyrimidine
CAS 478029-67-3C18H16N2O2
5-Methoxy-4-(3-methylphenoxy)-2-phenylpyrimidine chemical structure, C18H16N2O2, CAS 478029-68-4
5-Methoxy-4-(3-methylphenoxy)-2-phenylpyrimidine
CAS 478029-68-4C18H16N2O2
4-(4-Chloro-2-methylphenoxy)-5-methoxy-2-phenylpyrimidine chemical structure, C18H15ClN2O2, CAS 478029-69-5
4-(4-Chloro-2-methylphenoxy)-5-methoxy-2-phenylpyrimidine
CAS 478029-69-5C18H15ClN2O2
5-Methoxy-4-(3-nitrophenoxy)-2-phenylpyrimidine chemical structure, C17H13N3O4, CAS 478029-73-1
5-Methoxy-4-(3-nitrophenoxy)-2-phenylpyrimidine
CAS 478029-73-1C17H13N3O4
5-Methoxy-4-phenoxy-2-[3-(trifluoromethyl)phenyl]pyrimidine chemical structure, C18H13F3N2O2, CAS 478030-31-8
5-Methoxy-4-phenoxy-2-[3-(trifluoromethyl)phenyl]pyrimidine
CAS 478030-31-8C18H13F3N2O2
5-Methoxy-4-[3-(trifluoromethyl)phenoxy]-2-[3-(trifluoromethyl)phenyl]pyrimidine chemical structure, C19H12F6N2O2, CAS 861209-11-2
5-Methoxy-4-[3-(trifluoromethyl)phenoxy]-2-[3-(trifluoromethyl)phenyl]pyrimidine
CAS 861209-11-2C19H12F6N2O2
Ethyl 2-phenyl-4-[3-(trifluoromethyl)phenoxy]pyrimidine-5-carboxylate chemical structure, C20H15F3N2O3, CAS 477854-65-2
Ethyl 2-phenyl-4-[3-(trifluoromethyl)phenoxy]pyrimidine-5-carboxylate
CAS 477854-65-2C20H15F3N2O3
Ethyl 4-(3,4-dichlorophenoxy)-2-phenyl-5-pyrimidinecarboxylate chemical structure, C19H14Cl2N2O3, CAS 477854-68-5
Ethyl 4-(3,4-dichlorophenoxy)-2-phenyl-5-pyrimidinecarboxylate
CAS 477854-68-5C19H14Cl2N2O3
Ethyl 4-phenoxy-2-phenyl-5-pyrimidinecarboxylate chemical structure, C19H16N2O3, CAS 477854-77-6
Ethyl 4-phenoxy-2-phenyl-5-pyrimidinecarboxylate
CAS 477854-77-6C19H16N2O3
Ethyl 4-(4-chlorophenoxy)-2-phenyl-5-pyrimidinecarboxylate chemical structure, C19H15ClN2O3, CAS 477854-78-7
Ethyl 4-(4-chlorophenoxy)-2-phenyl-5-pyrimidinecarboxylate
CAS 477854-78-7C19H15ClN2O3
Ethyl 4-(2,3-dimethylphenoxy)-2-phenyl-5-pyrimidinecarboxylate chemical structure, C21H20N2O3, CAS 477854-79-8
Ethyl 4-(2,3-dimethylphenoxy)-2-phenyl-5-pyrimidinecarboxylate
CAS 477854-79-8C21H20N2O3
Ethyl 4-(4-methylphenoxy)-2-phenyl-5-pyrimidinecarboxylate chemical structure, C20H18N2O3, CAS 477854-80-1
Ethyl 4-(4-methylphenoxy)-2-phenyl-5-pyrimidinecarboxylate
CAS 477854-80-1C20H18N2O3
Ethyl 4-(4-fluorophenoxy)-2-phenyl-5-pyrimidinecarboxylate chemical structure, C19H15FN2O3, CAS 477854-81-2
Ethyl 4-(4-fluorophenoxy)-2-phenyl-5-pyrimidinecarboxylate
CAS 477854-81-2C19H15FN2O3
Ethyl 4-(4-methoxyphenoxy)-2-phenyl-5-pyrimidinecarboxylate chemical structure, C20H18N2O4, CAS 477854-83-4
Ethyl 4-(4-methoxyphenoxy)-2-phenyl-5-pyrimidinecarboxylate
CAS 477854-83-4C20H18N2O4
Ethyl 4-(3-chlorophenoxy)-2-phenyl-5-pyrimidinecarboxylate chemical structure, C19H15ClN2O3, CAS 477854-84-5
Ethyl 4-(3-chlorophenoxy)-2-phenyl-5-pyrimidinecarboxylate
CAS 477854-84-5C19H15ClN2O3
4-Phenoxy-2-phenylpyrimidine-5-carboxylic acid chemical structure, C17H12N2O3, CAS 477854-85-6
4-Phenoxy-2-phenylpyrimidine-5-carboxylic acid
CAS 477854-85-6C17H12N2O3
4-(4-Fluorophenoxy)-2-phenylpyrimidine-5-carboxylic acid chemical structure, C17H11FN2O3, CAS 477854-86-7
4-(4-Fluorophenoxy)-2-phenylpyrimidine-5-carboxylic acid
CAS 477854-86-7C17H11FN2O3
4-(4-Chlorophenoxy)-6-[(methylsulfonyl)methyl]-2-phenylpyrimidine chemical structure, C18H15ClN2O3S, CAS 339279-13-9
4-(4-Chlorophenoxy)-6-[(methylsulfonyl)methyl]-2-phenylpyrimidine
CAS 339279-13-9C18H15ClN2O3S
4-Chloro-6-(4-methylphenoxy)-2-phenylpyrimidine chemical structure, C17H13ClN2O, CAS 343373-73-9
4-Chloro-6-(4-methylphenoxy)-2-phenylpyrimidine
CAS 343373-73-9C17H13ClN2O
4-(4-Fluorophenoxy)-5-(methylsulfonyl)-2-phenylpyrimidine chemical structure, C17H13FN2O3S, CAS 478080-85-2
4-(4-Fluorophenoxy)-5-(methylsulfonyl)-2-phenylpyrimidine
CAS 478080-85-2C17H13FN2O3S