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Murcko scaffold

Ring system with 3 rings and 19 atoms

59 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
59
With full pages
13
Scaffold SMILES

c1ccc(Oc2cccc(-c3ccccc3)n2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Oc2cccc(-c3ccccc3)n2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 59 chemicals

2-(3,5-Dimethylphenoxy)-4-methyl-3-(methylsulfonyl)-6-phenylpyridine chemical structure, C21H21NO3S, CAS 477845-40-2
2-(3,5-Dimethylphenoxy)-4-methyl-3-(methylsulfonyl)-6-phenylpyridine
CAS 477845-40-2C21H21NO3S
2-(2,3-Dimethylphenoxy)-4-methyl-3-(methylsulfonyl)-6-phenylpyridine chemical structure, C21H21NO3S, CAS 477845-41-3
2-(2,3-Dimethylphenoxy)-4-methyl-3-(methylsulfonyl)-6-phenylpyridine
CAS 477845-41-3C21H21NO3S
2-(4-Methoxyphenoxy)-6-phenyl-4-(trifluoromethyl)nicotinonitrile chemical structure, C20H13F3N2O2, CAS 338749-41-0
2-(4-Methoxyphenoxy)-6-phenyl-4-(trifluoromethyl)nicotinonitrile
CAS 338749-41-0C20H13F3N2O2
2-Phenoxy-6-phenyl-4-(trifluoromethyl)nicotinonitrile chemical structure, C19H11F3N2O, CAS 338749-44-3
2-Phenoxy-6-phenyl-4-(trifluoromethyl)nicotinonitrile
CAS 338749-44-3C19H11F3N2O
2-(4-Chlorophenoxy)-6-phenyl-4-(trifluoromethyl)nicotinonitrile chemical structure, C19H10ClF3N2O, CAS 338749-45-4
2-(4-Chlorophenoxy)-6-phenyl-4-(trifluoromethyl)nicotinonitrile
CAS 338749-45-4C19H10ClF3N2O
6-(4-Chlorophenyl)-2-(2,4-difluorophenoxy)-4-(trifluoromethyl)pyridine-3-carbonitrile chemical structure, C19H8ClF5N2O, CAS 478043-49-1
6-(4-Chlorophenyl)-2-(2,4-difluorophenoxy)-4-(trifluoromethyl)pyridine-3-carbonitrile
CAS 478043-49-1C19H8ClF5N2O
2-(2-Methoxyphenoxy)-4-methyl-3-(methylsulfonyl)-6-phenylpyridine chemical structure, C20H19NO4S, CAS 478245-50-0
2-(2-Methoxyphenoxy)-4-methyl-3-(methylsulfonyl)-6-phenylpyridine
CAS 478245-50-0C20H19NO4S
2-[4-(tert-Butyl)phenoxy]-4-methyl-6-phenyl-3-pyridinyl methyl sulfone chemical structure, C23H25NO3S, CAS 478245-55-5
2-[4-(tert-Butyl)phenoxy]-4-methyl-6-phenyl-3-pyridinyl methyl sulfone
CAS 478245-55-5C23H25NO3S
4-Methyl-3-(methylsulfonyl)-6-phenyl-2-[3-(trifluoromethyl)phenoxy]pyridine chemical structure, C20H16F3NO3S, CAS 478245-56-6
4-Methyl-3-(methylsulfonyl)-6-phenyl-2-[3-(trifluoromethyl)phenoxy]pyridine
CAS 478245-56-6C20H16F3NO3S
2-(4-Chlorophenoxy)-6-phenylpyridine-3-carbonitrile chemical structure, C18H11ClN2O, CAS 252058-97-2
2-(4-Chlorophenoxy)-6-phenylpyridine-3-carbonitrile
CAS 252058-97-2C18H11ClN2O
2-(3,4-Dichlorophenoxy)-6-phenylnicotinonitrile chemical structure, C18H10Cl2N2O, CAS 252058-98-3
2-(3,4-Dichlorophenoxy)-6-phenylnicotinonitrile
CAS 252058-98-3C18H10Cl2N2O
6-Phenyl-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carbonitrile chemical structure, C19H11F3N2O, CAS 252058-99-4
6-Phenyl-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carbonitrile
CAS 252058-99-4C19H11F3N2O
2-(2-Chlorophenoxy)-6-(4-chlorophenyl)pyridine-3-carbonitrile chemical structure, C18H10Cl2N2O, CAS 252059-09-9
2-(2-Chlorophenoxy)-6-(4-chlorophenyl)pyridine-3-carbonitrile
CAS 252059-09-9C18H10Cl2N2O
6-(4-Chlorophenyl)-2-phenoxypyridine-3-carbonitrile chemical structure, C18H11ClN2O, CAS 252059-10-2
6-(4-Chlorophenyl)-2-phenoxypyridine-3-carbonitrile
CAS 252059-10-2C18H11ClN2O
6-(4-Chlorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carbonitrile chemical structure, C19H10ClF3N2O, CAS 252059-11-3
6-(4-Chlorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carbonitrile
CAS 252059-11-3C19H10ClF3N2O
6-(4-Chlorophenyl)-2-(4-fluorophenoxy)pyridine-3-carbonitrile chemical structure, C18H10ClFN2O, CAS 252059-12-4
6-(4-Chlorophenyl)-2-(4-fluorophenoxy)pyridine-3-carbonitrile
CAS 252059-12-4C18H10ClFN2O
6-(4-Chlorophenyl)-2-(2,4-difluorophenoxy)pyridine-3-carbonitrile chemical structure, C18H9ClF2N2O, CAS 252059-13-5
6-(4-Chlorophenyl)-2-(2,4-difluorophenoxy)pyridine-3-carbonitrile
CAS 252059-13-5C18H9ClF2N2O
2-(2-Chlorophenoxy)-6-(3,4-dichlorophenyl)pyridine-3-carbonitrile chemical structure, C18H9Cl3N2O, CAS 252059-68-0
2-(2-Chlorophenoxy)-6-(3,4-dichlorophenyl)pyridine-3-carbonitrile
CAS 252059-68-0C18H9Cl3N2O
6-(3,4-Dichlorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carbonitrile chemical structure, C19H9Cl2F3N2O, CAS 252059-70-4
6-(3,4-Dichlorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carbonitrile
CAS 252059-70-4C19H9Cl2F3N2O
2-(2,4-Dichlorophenoxy)-6-(3,4-dichlorophenyl)pyridine-3-carbonitrile chemical structure, C18H8Cl4N2O, CAS 252059-72-6
2-(2,4-Dichlorophenoxy)-6-(3,4-dichlorophenyl)pyridine-3-carbonitrile
CAS 252059-72-6C18H8Cl4N2O
2-(3,4-Dichlorophenoxy)-6-(3,4-dichlorophenyl)pyridine-3-carbonitrile chemical structure, C18H8Cl4N2O, CAS 252059-74-8
2-(3,4-Dichlorophenoxy)-6-(3,4-dichlorophenyl)pyridine-3-carbonitrile
CAS 252059-74-8C18H8Cl4N2O
6-(3,4-Dichlorophenyl)-2-(4-fluorophenoxy)pyridine-3-carbonitrile chemical structure, C18H9Cl2FN2O, CAS 252059-76-0
6-(3,4-Dichlorophenyl)-2-(4-fluorophenoxy)pyridine-3-carbonitrile
CAS 252059-76-0C18H9Cl2FN2O
2-(2,3-Dichlorophenoxy)-6-(3,4-dichlorophenyl)pyridine-3-carbonitrile chemical structure, C18H8Cl4N2O, CAS 252059-77-1
2-(2,3-Dichlorophenoxy)-6-(3,4-dichlorophenyl)pyridine-3-carbonitrile
CAS 252059-77-1C18H8Cl4N2O
2-(3,5-Dichlorophenoxy)-6-(3,4-dichlorophenyl)pyridine-3-carbonitrile chemical structure, C18H8Cl4N2O, CAS 252059-78-2
2-(3,5-Dichlorophenoxy)-6-(3,4-dichlorophenyl)pyridine-3-carbonitrile
CAS 252059-78-2C18H8Cl4N2O