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Murcko scaffold

Ring system with 3 rings and 21 atoms

9 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
9
With full pages
5
Scaffold SMILES

O=C(Nc1ccc(N2CCOCC2)nc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccc(N2CCOCC2)nc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

4-Chloro-N-(6-morpholino-3-pyridinyl)benzenecarboxamide chemical structure, C16H16ClN3O2, CAS 860650-11-9
4-Chloro-N-(6-morpholino-3-pyridinyl)benzenecarboxamide
CAS 860650-11-9C16H16ClN3O2
4-Methyl-N-(6-morpholino-3-pyridinyl)benzenecarboxamide chemical structure, C17H19N3O2, CAS 383146-15-4
4-Methyl-N-(6-morpholino-3-pyridinyl)benzenecarboxamide
CAS 383146-15-4C17H19N3O2
N-(6-Morpholino-3-pyridinyl)-4-(trifluoromethyl)benzenecarboxamide chemical structure, C17H16F3N3O2, CAS 383146-25-6
N-(6-Morpholino-3-pyridinyl)-4-(trifluoromethyl)benzenecarboxamide
CAS 383146-25-6C17H16F3N3O2
2-Methyl-N-(6-morpholino-3-pyridinyl)benzenecarboxamide chemical structure, C17H19N3O2, CAS 383146-21-2
2-Methyl-N-(6-morpholino-3-pyridinyl)benzenecarboxamide
CAS 383146-21-2C17H19N3O2
4-Fluoro-N-(6-morpholino-3-pyridinyl)benzenecarboxamide chemical structure, C16H16FN3O2, CAS 383146-19-8
4-Fluoro-N-(6-morpholino-3-pyridinyl)benzenecarboxamide
CAS 383146-19-8C16H16FN3O2
3,4-Difluoro-N-[6-(morpholin-4-yl)pyridin-3-yl]benzamide chemical structure, C16H15F2N3O2, CAS 931611-21-1
3,4-Difluoro-N-[6-(morpholin-4-yl)pyridin-3-yl]benzamide
CAS 931611-21-1C16H15F2N3O2
N-[6-(Morpholin-4-yl)pyridin-3-yl]-4-(prop-2-enamido)benzamide chemical structure, C19H20N4O3, CAS 1210680-89-9
N-[6-(Morpholin-4-yl)pyridin-3-yl]-4-(prop-2-enamido)benzamide
CAS 1210680-89-9C19H20N4O3
3-Bromo-N-(6-((2R,6S)-2,6-dimethylmorpholino)pyridin-3-yl)-2-methylbenzamide chemical structure, C19H22BrN3O2, CAS 1221721-86-3
3-Bromo-N-(6-((2R,6S)-2,6-dimethylmorpholino)pyridin-3-yl)-2-methylbenzamide
CAS 1221721-86-3C19H22BrN3O2
rel-3-Bromo-N-[6-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-3-pyridinyl]-4-methylbenzamide chemical structure, C19H22BrN3O2, CAS 956699-07-3
rel-3-Bromo-N-[6-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-3-pyridinyl]-4-methylbenzamide
CAS 956699-07-3C19H22BrN3O2