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Murcko scaffold

Ring system with 3 rings and 21 atoms

257 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
257
With full pages
35
Scaffold SMILES

O=C(Nc1ccc(N2CCNCC2)cc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccc(N2CCNCC2)cc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 257 chemicals

3,5-Dibromo-2-hydroxy-N-[4-(4-methylpiperazin-1-yl)-3-nitrophenyl]benzamide chemical structure, C18H18Br2N4O4, CAS 72670-71-4
3,5-Dibromo-2-hydroxy-N-[4-(4-methylpiperazin-1-yl)-3-nitrophenyl]benzamide
CAS 72670-71-4C18H18Br2N4O4
N-[4-(4-Butanoylpiperazin-1-yl)phenyl]benzamide chemical structure, C21H25N3O2, CAS 688028-61-7
N-[4-(4-Butanoylpiperazin-1-yl)phenyl]benzamide
CAS 688028-61-7C21H25N3O2
2-Chloro-N-[4-(4-ethylpiperazin-1-yl)phenyl]benzamide chemical structure, C19H22ClN3O, CAS 328275-87-2
2-Chloro-N-[4-(4-ethylpiperazin-1-yl)phenyl]benzamide
CAS 328275-87-2C19H22ClN3O
N-[4-(4-Acetylpiperazin-1-yl)phenyl]-4-fluorobenzamide chemical structure, C19H20FN3O2, CAS 380590-87-4
N-[4-(4-Acetylpiperazin-1-yl)phenyl]-4-fluorobenzamide
CAS 380590-87-4C19H20FN3O2
N-[4-(4-Methylpiperazin-1-yl)phenyl]benzamide chemical structure, C18H21N3O, CAS 448199-04-0
N-[4-(4-Methylpiperazin-1-yl)phenyl]benzamide
CAS 448199-04-0C18H21N3O
3-Ethoxy-N-[4-(4-methylpiperazin-1-yl)phenyl]benzamide chemical structure, C20H25N3O2, CAS 640241-56-1
3-Ethoxy-N-[4-(4-methylpiperazin-1-yl)phenyl]benzamide
CAS 640241-56-1C20H25N3O2
4-Ethoxy-N-[4-(4-methyl-1-piperazinyl)phenyl]benzamide chemical structure, C20H25N3O2, CAS 640241-60-7
4-Ethoxy-N-[4-(4-methyl-1-piperazinyl)phenyl]benzamide
CAS 640241-60-7C20H25N3O2
2-Chloro-4-methyl-N-[4-(4-methyl-1-piperazinyl)phenyl]benzamide chemical structure, C19H22ClN3O, CAS 640242-10-0
2-Chloro-4-methyl-N-[4-(4-methyl-1-piperazinyl)phenyl]benzamide
CAS 640242-10-0C19H22ClN3O
N-[4-(4-Acetylpiperazin-1-yl)phenyl]-2-fluorobenzamide chemical structure, C19H20FN3O2, CAS 355412-28-1
N-[4-(4-Acetylpiperazin-1-yl)phenyl]-2-fluorobenzamide
CAS 355412-28-1C19H20FN3O2
N-[4-(4-Acetylpiperazin-1-yl)phenyl]-3-methylbenzamide chemical structure, C20H23N3O2, CAS 425420-28-6
N-[4-(4-Acetylpiperazin-1-yl)phenyl]-3-methylbenzamide
CAS 425420-28-6C20H23N3O2
2-Methoxy-N-[4-(4-methylpiperazin-1-yl)phenyl]benzamide chemical structure, C19H23N3O2, CAS 573936-43-3
2-Methoxy-N-[4-(4-methylpiperazin-1-yl)phenyl]benzamide
CAS 573936-43-3C19H23N3O2
3-Methyl-N-[4-(4-methylpiperazin-1-yl)phenyl]benzamide chemical structure, C19H23N3O, CAS 303150-75-6
3-Methyl-N-[4-(4-methylpiperazin-1-yl)phenyl]benzamide
CAS 303150-75-6C19H23N3O
4-Methyl-N-[4-(4-methylpiperazin-1-yl)phenyl]benzamide chemical structure, C19H23N3O, CAS 640241-46-9
4-Methyl-N-[4-(4-methylpiperazin-1-yl)phenyl]benzamide
CAS 640241-46-9C19H23N3O
N-[4-(4-Methylpiperazin-1-yl)phenyl]-4-propan-2-ylbenzamide chemical structure, C21H27N3O, CAS 640241-50-5
N-[4-(4-Methylpiperazin-1-yl)phenyl]-4-propan-2-ylbenzamide
CAS 640241-50-5C21H27N3O
4-Ethyl-N-[4-(4-methylpiperazin-1-yl)phenyl]benzamide chemical structure, C20H25N3O, CAS 640241-48-1
4-Ethyl-N-[4-(4-methylpiperazin-1-yl)phenyl]benzamide
CAS 640241-48-1C20H25N3O
4-Chloro-N-[4-(4-ethylpiperazin-1-yl)phenyl]benzamide chemical structure, C19H22ClN3O, CAS 690215-61-3
4-Chloro-N-[4-(4-ethylpiperazin-1-yl)phenyl]benzamide
CAS 690215-61-3C19H22ClN3O
2-Methoxy-3-methyl-N-[4-(4-methylpiperazin-1-yl)phenyl]benzamide chemical structure, C20H25N3O2, CAS 689747-53-3
2-Methoxy-3-methyl-N-[4-(4-methylpiperazin-1-yl)phenyl]benzamide
CAS 689747-53-3C20H25N3O2
N-[4-(4-Acetyl-piperazin-1-yl)-phenyl]-3-fluoro-benzamide chemical structure, C19H20FN3O2, CAS 590380-67-9
N-[4-(4-Acetyl-piperazin-1-yl)-phenyl]-3-fluoro-benzamide
CAS 590380-67-9C19H20FN3O2
3-Chloro-4-methyl-N-[4-(4-methylpiperazin-1-yl)phenyl]benzamide chemical structure, C19H22ClN3O, CAS 689747-38-4
3-Chloro-4-methyl-N-[4-(4-methylpiperazin-1-yl)phenyl]benzamide
CAS 689747-38-4C19H22ClN3O
3-Chloro-N-[4-(4-methylpiperazin-1-yl)phenyl]benzamide chemical structure, C18H20ClN3O, CAS 303150-61-0
3-Chloro-N-[4-(4-methylpiperazin-1-yl)phenyl]benzamide
CAS 303150-61-0C18H20ClN3O
3-Methoxy-N-[4-(4-methylpiperazin-1-yl)phenyl]benzamide chemical structure, C19H23N3O2, CAS 689746-67-6
3-Methoxy-N-[4-(4-methylpiperazin-1-yl)phenyl]benzamide
CAS 689746-67-6C19H23N3O2
4-Fluoro-N-[4-(4-methylpiperazin-1-yl)phenyl]benzamide chemical structure, C18H20FN3O, CAS 689747-22-6
4-Fluoro-N-[4-(4-methylpiperazin-1-yl)phenyl]benzamide
CAS 689747-22-6C18H20FN3O
3-Fluoro-N-[4-(4-methylpiperazin-1-yl)phenyl]benzamide chemical structure, C18H20FN3O, CAS 689747-16-8
3-Fluoro-N-[4-(4-methylpiperazin-1-yl)phenyl]benzamide
CAS 689747-16-8C18H20FN3O
N-[4-(4-Ethylpiperazin-1-yl)phenyl]-4-methylbenzamide chemical structure, C20H25N3O, CAS 478065-83-7
N-[4-(4-Ethylpiperazin-1-yl)phenyl]-4-methylbenzamide
CAS 478065-83-7C20H25N3O