Murcko scaffold
2-(1H-Indol-3-yl)-1-(4-phenylpiperazin-1-yl)ethanone scaffold
6 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 24
- Chemicals
- 6
- With full pages
- 2
Scaffold SMILES
O=C(Cc1c[nH]c2ccccc12)N1CCN(c2ccccc2)CC1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 6 of 6 chemicals
2-(1H-Indol-3-yl)-1-[4-(4-methoxyphenyl)piperazin-1-yl]ethanone
CAS 782466-68-6C21H23N3O2
2-(1H-Indol-3-yl)-1-(4-phenylpiperazin-1-yl)ethanone
CAS 81807-97-8C20H21N3O
1-[4-(3-Chlorophenyl)piperazin-1-yl]-2-(1H-indol-3-yl)ethanone
CAS 794555-94-5C20H20ClN3O
1-(4-(2-Fluorophenyl)piperazin-1-yl)-2-(1-methyl-1H-indol-3-yl)ethanone
CAS 901222-10-4C21H22FN3O
1-(4-(3-Chlorophenyl)piperazin-1-yl)-2-(1-methyl-1H-indol-3-yl)ethanone
CAS 901222-17-1C21H22ClN3O
2-(1-Methyl-1H-indol-3-yl)-1-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)ethanone
CAS 901222-41-1C22H22F3N3O