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Murcko scaffold

3-(2-(4-Phenyl-1-piperazinyl)ethyl)oxazolo(4,5-b)pyridin-2(3H)-one scaffold

7 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
7
With full pages
1
Scaffold SMILES

O=c1oc2cccnc2n1CCN1CCN(c2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3-(2-(4-Phenyl-1-piperazinyl)ethyl)oxazolo(4,5-b)pyridin-2(3H)-one page
Murcko scaffold O=c1oc2cccnc2n1CCN1CCN(c2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

3-(2-(4-Phenyl-1-piperazinyl)ethyl)oxazolo(4,5-b)pyridin-2(3H)-one chemical structure, C18H20N4O2, CAS 134336-97-3
3-(2-(4-Phenyl-1-piperazinyl)ethyl)oxazolo(4,5-b)pyridin-2(3H)-one
CAS 134336-97-3C18H20N4O2
3-(2-(4-(3-(Trifluoromethyl)phenyl)-1-piperazinyl)ethyl)oxazolo(4,5-b)pyridin-2(3H)-one chemical structure, C19H19F3N4O2, CAS 134336-98-4
3-(2-(4-(3-(Trifluoromethyl)phenyl)-1-piperazinyl)ethyl)oxazolo(4,5-b)pyridin-2(3H)-one
CAS 134336-98-4C19H19F3N4O2
Oxazolo(4,5-b)pyridin-2(3H)-one, 3-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)- chemical structure, C19H22N4O3, CAS 134337-01-2
Oxazolo(4,5-b)pyridin-2(3H)-one, 3-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-
CAS 134337-01-2C19H22N4O3
Oxazolo(4,5-b)pyridin-2(3H)-one, 3-(2-(4-(4-fluorophenyl)-1-piperazinyl)ethyl)- chemical structure, C18H19FN4O2, CAS 134337-03-4
Oxazolo(4,5-b)pyridin-2(3H)-one, 3-(2-(4-(4-fluorophenyl)-1-piperazinyl)ethyl)-
CAS 134337-03-4C18H19FN4O2
Oxazolo(4,5-b)pyridin-2(3H)-one, 3-(2-(4-(4-chlorophenyl)-1-piperazinyl)ethyl)- chemical structure, C18H19ClN4O2, CAS 134337-05-6
Oxazolo(4,5-b)pyridin-2(3H)-one, 3-(2-(4-(4-chlorophenyl)-1-piperazinyl)ethyl)-
CAS 134337-05-6C18H19ClN4O2
Oxazolo(4,5-b)pyridin-2(3H)-one, 5-methyl-3-(2-(4-phenyl-1-piperazinyl)ethyl)- chemical structure, C19H22N4O2, CAS 134337-07-8
Oxazolo(4,5-b)pyridin-2(3H)-one, 5-methyl-3-(2-(4-phenyl-1-piperazinyl)ethyl)-
CAS 134337-07-8C19H22N4O2
Oxazolo(4,5-b)pyridin-2(3H)-one, 6-bromo-3-(2-(4-phenyl-1-piperazinyl)ethyl)- chemical structure, C18H19BrN4O2, CAS 134337-08-9
Oxazolo(4,5-b)pyridin-2(3H)-one, 6-bromo-3-(2-(4-phenyl-1-piperazinyl)ethyl)-
CAS 134337-08-9C18H19BrN4O2