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Murcko scaffold

Ring system with 2 rings and 10 atoms

52 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
52
With full pages
3
Scaffold SMILES

c1nc(C2OCCO2)cs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1nc(C2OCCO2)cs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 52 chemicals

2-Bromo-4-(1,3-dioxolan-2-yl)thiazole chemical structure, C6H6BrNO2S, CAS 231278-12-9
2-Bromo-4-(1,3-dioxolan-2-yl)thiazole
CAS 231278-12-9C6H6BrNO2S
4-(2-Methyl-1,3-dioxolan-2-yl)-2-thiazolemethanol chemical structure, C8H11NO3S, CAS 1161775-07-0
4-(2-Methyl-1,3-dioxolan-2-yl)-2-thiazolemethanol
CAS 1161775-07-0C8H11NO3S
[4-(2-Methyl-[1,3]dioxolan-2-yl)-thiazol-2-yl]-methylamine chemical structure, C8H12N2O2S, CAS 1256276-13-7
[4-(2-Methyl-[1,3]dioxolan-2-yl)-thiazol-2-yl]-methylamine
CAS 1256276-13-7C8H12N2O2S
[4-(1,3-Dioxolan-2-yl)-1,3-thiazol-2-yl]methanamine chemical structure, C7H10N2O2S, CAS 2060042-51-3
[4-(1,3-Dioxolan-2-yl)-1,3-thiazol-2-yl]methanamine
CAS 2060042-51-3C7H10N2O2S
4-(1,3-Dioxolan-2-yl)-1,3-thiazole-2-carboxylic acid chemical structure, C7H7NO4S, CAS 2060034-80-0
4-(1,3-Dioxolan-2-yl)-1,3-thiazole-2-carboxylic acid
CAS 2060034-80-0C7H7NO4S
4-(1,3-Dioxolan-2-yl)-1,3-thiazole-2-carbonitrile chemical structure, C7H6N2O2S, CAS 2060020-86-0
4-(1,3-Dioxolan-2-yl)-1,3-thiazole-2-carbonitrile
CAS 2060020-86-0C7H6N2O2S
4-(1,3-Dioxolan-2-yl)-1,3-thiazole-2-carbaldehyde chemical structure, C7H7NO3S, CAS 1934392-21-8
4-(1,3-Dioxolan-2-yl)-1,3-thiazole-2-carbaldehyde
CAS 1934392-21-8C7H7NO3S
[4-(1,3-Dioxolan-2-yl)-1,3-thiazol-2-yl]methanol chemical structure, C7H9NO3S, CAS 1934407-64-3
[4-(1,3-Dioxolan-2-yl)-1,3-thiazol-2-yl]methanol
CAS 1934407-64-3C7H9NO3S
2-(tert-Butyl-dimethyl-silanyloxymethyl)-4-(2-methyl-[1,3]dioxolan-2-yl)-thiazole chemical structure, C14H25NO3SSi, CAS 1161775-05-8
2-(tert-Butyl-dimethyl-silanyloxymethyl)-4-(2-methyl-[1,3]dioxolan-2-yl)-thiazole
CAS 1161775-05-8C14H25NO3SSi
Methyl 4-(1,3-dioxolan-2-yl)-5-formyl-1,3-thiazole-2-carboxylate chemical structure, C9H9NO5S, CAS 2248411-79-0
Methyl 4-(1,3-dioxolan-2-yl)-5-formyl-1,3-thiazole-2-carboxylate
CAS 2248411-79-0C9H9NO5S
5-(Difluoromethyl)-4-(1,3-dioxolan-2-yl)-1,3-thiazole-2-carboxylic acid chemical structure, C8H7F2NO4S, CAS 2248376-85-2
5-(Difluoromethyl)-4-(1,3-dioxolan-2-yl)-1,3-thiazole-2-carboxylic acid
CAS 2248376-85-2C8H7F2NO4S
2-Bromo-5-(difluoromethyl)-4-(1,3-dioxolan-2-yl)-1,3-thiazole chemical structure, C7H6BrF2NO2S, CAS 2248303-82-2
2-Bromo-5-(difluoromethyl)-4-(1,3-dioxolan-2-yl)-1,3-thiazole
CAS 2248303-82-2C7H6BrF2NO2S
2-Bromo-4-(1,3-dioxolan-2-yl)-1,3-thiazole-5-carbaldehyde chemical structure, C7H6BrNO3S, CAS 2174007-96-4
2-Bromo-4-(1,3-dioxolan-2-yl)-1,3-thiazole-5-carbaldehyde
CAS 2174007-96-4C7H6BrNO3S
2-Bromo-4-(1,3-dioxolan-2-yl)-1,3-thiazole-5-carboxylic acid chemical structure, C7H6BrNO4S, CAS 2193059-42-4
2-Bromo-4-(1,3-dioxolan-2-yl)-1,3-thiazole-5-carboxylic acid
CAS 2193059-42-4C7H6BrNO4S
2-Chloro-4-(1,3-dioxolan-2-yl)-1,3-thiazole-5-sulfonyl chloride chemical structure, C6H5Cl2NO4S2, CAS 2470439-48-4
2-Chloro-4-(1,3-dioxolan-2-yl)-1,3-thiazole-5-sulfonyl chloride
CAS 2470439-48-4C6H5Cl2NO4S2
2-Chloro-4-(1,3-dioxolan-2-yl)-1,3-thiazole-5-sulfonamide chemical structure, C6H7ClN2O4S2, CAS 2470439-65-5
2-Chloro-4-(1,3-dioxolan-2-yl)-1,3-thiazole-5-sulfonamide
CAS 2470439-65-5C6H7ClN2O4S2
1-[4-(1,3-Dioxolan-2-yl)-1,3-thiazol-2-yl]-2,2-dimethylpropan-1-one chemical structure, C11H15NO3S, CAS 2166951-79-5
1-[4-(1,3-Dioxolan-2-yl)-1,3-thiazol-2-yl]-2,2-dimethylpropan-1-one
CAS 2166951-79-5C11H15NO3S
1-[4-(1,3-Dioxolan-2-yl)-1,3-thiazol-2-yl]-2,2,2-trifluoroethan-1-one chemical structure, C8H6F3NO3S, CAS 2168835-27-4
1-[4-(1,3-Dioxolan-2-yl)-1,3-thiazol-2-yl]-2,2,2-trifluoroethan-1-one
CAS 2168835-27-4C8H6F3NO3S
3-Methyl-1-[4-(2-methyl-1,3-dioxolan-2-yl)-1,3-thiazol-2-yl]butan-1-one chemical structure, C12H17NO3S, CAS 2169172-30-7
3-Methyl-1-[4-(2-methyl-1,3-dioxolan-2-yl)-1,3-thiazol-2-yl]butan-1-one
CAS 2169172-30-7C12H17NO3S
2-Methyl-1-[4-(2-methyl-1,3-dioxolan-2-yl)-1,3-thiazol-2-yl]propan-1-one chemical structure, C11H15NO3S, CAS 2167517-17-9
2-Methyl-1-[4-(2-methyl-1,3-dioxolan-2-yl)-1,3-thiazol-2-yl]propan-1-one
CAS 2167517-17-9C11H15NO3S
1-[4-(1,3-Dioxolan-2-yl)-1,3-thiazol-2-yl]propan-1-one chemical structure, C9H11NO3S, CAS 2167954-52-9
1-[4-(1,3-Dioxolan-2-yl)-1,3-thiazol-2-yl]propan-1-one
CAS 2167954-52-9C9H11NO3S
3-[4-(1,3-Dioxolan-2-yl)-1,3-thiazol-2-yl]-3-oxopropanenitrile chemical structure, C9H8N2O3S, CAS 2168576-04-1
3-[4-(1,3-Dioxolan-2-yl)-1,3-thiazol-2-yl]-3-oxopropanenitrile
CAS 2168576-04-1C9H8N2O3S
3-Methoxy-1-[4-(2-methyl-1,3-dioxolan-2-yl)-1,3-thiazol-2-yl]propan-1-one chemical structure, C11H15NO4S, CAS 2168408-71-5
3-Methoxy-1-[4-(2-methyl-1,3-dioxolan-2-yl)-1,3-thiazol-2-yl]propan-1-one
CAS 2168408-71-5C11H15NO4S
4-(1,3-Dioxolan-2-yl)-1,3-thiazole-2-carbothioamide chemical structure, C7H8N2O2S2, CAS 2171871-76-2
4-(1,3-Dioxolan-2-yl)-1,3-thiazole-2-carbothioamide
CAS 2171871-76-2C7H8N2O2S2