Free for buyers, contact details stay privateFree for buyers. Your contact details stay private until you accept a quote.

Sign in Join free

Murcko scaffold

Ring system with 2 rings and 15 atoms

8 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 15
Chemicals: 8
With full pages: 3

Scaffold SMILES

O=C(C=Cc1ccc[nH]1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C(C=Cc1ccc[nH]1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

2-Propen-1-one, 3-(1-methyl-1H-pyrrol-2-yl)-1-phenyl- chemical structure, C14H13NO, CAS 16750-56-4

2-Propen-1-one, 3-(1-methyl-1H-pyrrol-2-yl)-1-phenyl-

CAS 16750-56-4C₁₄H₁₃NO

3-(3,5-Dimethyl-1H-pyrrol-2-yl)-1-[3-(trifluoromethyl)phenyl]prop-2-en-1-one chemical structure, C16H14F3NO, CAS 259544-84-8

3-(3,5-Dimethyl-1H-pyrrol-2-yl)-1-[3-(trifluoromethyl)phenyl]prop-2-en-1-one

CAS 259544-84-8C₁₆H₁₄F₃NO

(E)-1-(4-Fluorophenyl)-3-(1H-pyrrol-2-yl)prop-2-en-1-one chemical structure, C13H10FNO, CAS 28081-21-2

(E)-1-(4-Fluorophenyl)-3-(1H-pyrrol-2-yl)prop-2-en-1-one

CAS 28081-21-2C₁₃H₁₀FNO

(E)-2-Benzoyl-3-[4-(2-chloroacetyl)-1H-pyrrol-2-yl]prop-2-enenitrile chemical structure, C16H11ClN2O2, CAS 866038-40-6

(E)-2-Benzoyl-3-[4-(2-chloroacetyl)-1H-pyrrol-2-yl]prop-2-enenitrile

CAS 866038-40-6C₁₆H₁₁ClN₂O₂

N-[4-[(E)-3-(1H-Pyrrol-2-yl)prop-2-enoyl]phenyl]acetamide chemical structure, C15H14N2O2, CAS 1522230-08-5

N-[4-[(E)-3-(1H-Pyrrol-2-yl)prop-2-enoyl]phenyl]acetamide

CAS 1522230-08-5C₁₅H₁₄N₂O₂

(E)-1-Phenyl-3-(1H-pyrrol-2-yl)prop-2-en-1-one chemical structure, C13H11NO, CAS 22563-49-1

(E)-1-Phenyl-3-(1H-pyrrol-2-yl)prop-2-en-1-one

CAS 22563-49-1C₁₃H₁₁NO

(E)-beta-(1-Methyl-1H-pyrrole-2-yl)acrylophenone chemical structure, C14H13NO, CAS 22563-51-5

(E)-beta-(1-Methyl-1H-pyrrole-2-yl)acrylophenone

CAS 22563-51-5C₁₄H₁₃NO

1-(4-Ethenylphenyl)-3-(1H-pyrrol-2-yl)prop-2-en-1-one chemical structure, C15H13NO, CAS 60689-12-5

1-(4-Ethenylphenyl)-3-(1H-pyrrol-2-yl)prop-2-en-1-one

CAS 60689-12-5C₁₅H₁₃NO