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Murcko scaffold

Ring system with 3 rings and 21 atoms

15 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
15
With full pages
10
Scaffold SMILES

O=c1n(-c2ccccc2)cnn1CCOc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1n(-c2ccccc2)cnn1CCOc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

4-(4-Isopropylphenyl)-5-methyl-2-(2-phenoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one chemical structure, C20H23N3O2, CAS 860785-34-8
4-(4-Isopropylphenyl)-5-methyl-2-(2-phenoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one
CAS 860785-34-8C20H23N3O2
4-(4-Fluorophenyl)-5-methyl-2-(2-phenoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one chemical structure, C17H16FN3O2, CAS 860784-98-1
4-(4-Fluorophenyl)-5-methyl-2-(2-phenoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one
CAS 860784-98-1C17H16FN3O2
4-(2,6-Dimethylphenyl)-5-methyl-2-(2-phenoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one chemical structure, C19H21N3O2, CAS 860784-80-1
4-(2,6-Dimethylphenyl)-5-methyl-2-(2-phenoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one
CAS 860784-80-1C19H21N3O2
5-Methyl-2-(2-phenoxyethyl)-4-[3-(trifluoromethyl)phenyl]-1,2,4-triazol-3-one chemical structure, C18H16F3N3O2, CAS 861206-75-9
5-Methyl-2-(2-phenoxyethyl)-4-[3-(trifluoromethyl)phenyl]-1,2,4-triazol-3-one
CAS 861206-75-9C18H16F3N3O2
5-Methyl-2-(2-phenoxyethyl)-4-phenyl-1,2,4-triazol-3-one chemical structure, C17H17N3O2, CAS 861206-16-8
5-Methyl-2-(2-phenoxyethyl)-4-phenyl-1,2,4-triazol-3-one
CAS 861206-16-8C17H17N3O2
4-(2-Chlorophenyl)-5-methyl-2-(2-phenoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one chemical structure, C17H16ClN3O2, CAS 860789-89-5
4-(2-Chlorophenyl)-5-methyl-2-(2-phenoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one
CAS 860789-89-5C17H16ClN3O2
5-Methyl-4-(4-methylphenyl)-2-(2-phenoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one chemical structure, C18H19N3O2, CAS 861206-04-4
5-Methyl-4-(4-methylphenyl)-2-(2-phenoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one
CAS 861206-04-4C18H19N3O2
4-(4-Methoxyphenyl)-5-methyl-2-(2-phenoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one chemical structure, C18H19N3O3, CAS 861206-22-6
4-(4-Methoxyphenyl)-5-methyl-2-(2-phenoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one
CAS 861206-22-6C18H19N3O3
4-(2,6-Difluorophenyl)-5-methyl-2-(2-phenoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one chemical structure, C17H15F2N3O2, CAS 861206-34-0
4-(2,6-Difluorophenyl)-5-methyl-2-(2-phenoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one
CAS 861206-34-0C17H15F2N3O2
4-(3-Chlorophenyl)-5-methyl-2-(2-phenoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one chemical structure, C17H16ClN3O2, CAS 860786-41-0
4-(3-Chlorophenyl)-5-methyl-2-(2-phenoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one
CAS 860786-41-0C17H16ClN3O2
4-(3-Methoxyphenyl)-5-methyl-2-(2-phenoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one chemical structure, C18H19N3O3, CAS 860786-47-6
4-(3-Methoxyphenyl)-5-methyl-2-(2-phenoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one
CAS 860786-47-6C18H19N3O3
4-(4-Chlorophenyl)-5-methyl-2-(2-phenoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one chemical structure, C17H16ClN3O2, CAS 860786-58-9
4-(4-Chlorophenyl)-5-methyl-2-(2-phenoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one
CAS 860786-58-9C17H16ClN3O2
4-(3-Fluorophenyl)-5-methyl-2-(2-phenoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one chemical structure, C17H16FN3O2, CAS 860786-25-0
4-(3-Fluorophenyl)-5-methyl-2-(2-phenoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one
CAS 860786-25-0C17H16FN3O2
4-(2,4-Dimethoxyphenyl)-5-methyl-2-(2-phenoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one chemical structure, C19H21N3O4, CAS 861206-44-2
4-(2,4-Dimethoxyphenyl)-5-methyl-2-(2-phenoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one
CAS 861206-44-2C19H21N3O4
4-(2-Fluorophenyl)-5-methyl-2-(2-phenoxyethyl)-1,2,4-triazol-3-one chemical structure, C17H16FN3O2, CAS 860786-75-0
4-(2-Fluorophenyl)-5-methyl-2-(2-phenoxyethyl)-1,2,4-triazol-3-one
CAS 860786-75-0C17H16FN3O2