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Murcko scaffold

1-Phenyl-2-((5-phenyl-1,3,4-oxadiazol-2-yl)thio)ethanone scaffold

57 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
57
With full pages
10
Scaffold SMILES

O=C(CSc1nnc(-c2ccccc2)o1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-Phenyl-2-((5-phenyl-1,3,4-oxadiazol-2-yl)thio)ethanone page
Murcko scaffold O=C(CSc1nnc(-c2ccccc2)o1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 57 chemicals

2-((5-(2,4-Dichlorophenyl)-1,3,4-oxadiazol-2-yl)thio)-1-phenylethanone chemical structure, C16H10Cl2N2O2S, CAS 348593-64-6
2-((5-(2,4-Dichlorophenyl)-1,3,4-oxadiazol-2-yl)thio)-1-phenylethanone
CAS 348593-64-6C16H10Cl2N2O2S
1-Phenyl-2-((5-phenyl-1,3,4-oxadiazol-2-yl)thio)ethanone chemical structure, C16H12N2O2S, CAS 74087-90-4
1-Phenyl-2-((5-phenyl-1,3,4-oxadiazol-2-yl)thio)ethanone
CAS 74087-90-4C16H12N2O2S
2-((5-(4-Methoxyphenyl)-1,3,4-oxadiazol-2-yl)thio)-1-phenylethan-1-one chemical structure, C17H14N2O3S, CAS 332921-97-8
2-((5-(4-Methoxyphenyl)-1,3,4-oxadiazol-2-yl)thio)-1-phenylethan-1-one
CAS 332921-97-8C17H14N2O3S
1-(4-Methylphenyl)-2-[(5-phenyl-1,3,4-oxadiazol-2-yl)sulfanyl]ethanone chemical structure, C17H14N2O2S, CAS 484694-49-7
1-(4-Methylphenyl)-2-[(5-phenyl-1,3,4-oxadiazol-2-yl)sulfanyl]ethanone
CAS 484694-49-7C17H14N2O2S
1-(4-Methoxyphenyl)-2-[(5-phenyl-1,3,4-oxadiazol-2-yl)sulfanyl]ethanone chemical structure, C17H14N2O3S, CAS 690969-42-7
1-(4-Methoxyphenyl)-2-[(5-phenyl-1,3,4-oxadiazol-2-yl)sulfanyl]ethanone
CAS 690969-42-7C17H14N2O3S
2-{[5-(4-Fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-1-(4-methoxyphenyl)ethan-1-one chemical structure, C17H13FN2O3S, CAS 307325-75-3
2-{[5-(4-Fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-1-(4-methoxyphenyl)ethan-1-one
CAS 307325-75-3C17H13FN2O3S
1-(2-Fluorophenyl)-2-(5-o-tolyl-1,3,4-oxadiazol-2-ylthio)ethanone chemical structure, C17H13FN2O2S, CAS 484694-85-1
1-(2-Fluorophenyl)-2-(5-o-tolyl-1,3,4-oxadiazol-2-ylthio)ethanone
CAS 484694-85-1C17H13FN2O2S
2-{[5-(4-Methoxyphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-1-(4-methylphenyl)-1-ethanone chemical structure, C18H16N2O3S, CAS 459845-46-6
2-{[5-(4-Methoxyphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-1-(4-methylphenyl)-1-ethanone
CAS 459845-46-6C18H16N2O3S
2-((5-(4-Chlorophenyl)-1,3,4-oxadiazol-2-yl)thio)-1-phenylethanone chemical structure, C16H11ClN2O2S, CAS 74087-97-1
2-((5-(4-Chlorophenyl)-1,3,4-oxadiazol-2-yl)thio)-1-phenylethanone
CAS 74087-97-1C16H11ClN2O2S
2-{[5-(3-Bromophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-1-(4-methoxyphenyl)ethanone chemical structure, C17H13BrN2O3S, CAS 302552-39-2
2-{[5-(3-Bromophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-1-(4-methoxyphenyl)ethanone
CAS 302552-39-2C17H13BrN2O3S
2-[[5-(2-Bromophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-1-(2,5-dimethylphenyl)ethanone chemical structure, C18H15BrN2O2S, CAS 724437-99-4
2-[[5-(2-Bromophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-1-(2,5-dimethylphenyl)ethanone
CAS 724437-99-4C18H15BrN2O2S
1-(4-Bromophenyl)-2-{[5-(3-methylphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}ethanone chemical structure, C17H13BrN2O2S, CAS 694475-12-2
1-(4-Bromophenyl)-2-{[5-(3-methylphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}ethanone
CAS 694475-12-2C17H13BrN2O2S
1-(4-Bromophenyl)-2-[[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]ethanone chemical structure, C17H13BrN2O2S, CAS 371948-36-6
1-(4-Bromophenyl)-2-[[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]ethanone
CAS 371948-36-6C17H13BrN2O2S
2-((5-(2-Hydroxyphenyl)-1,3,4-oxadiazol-2-yl)thio)-1-(4-nitrophenyl)ethanone chemical structure, C16H11N3O5S, CAS 336180-27-9
2-((5-(2-Hydroxyphenyl)-1,3,4-oxadiazol-2-yl)thio)-1-(4-nitrophenyl)ethanone
CAS 336180-27-9C16H11N3O5S
1-(4-Chlorophenyl)-2-((5-(2-chlorophenyl)-1,3,4-oxadiazol-2-yl)thio)ethanone chemical structure, C16H10Cl2N2O2S, CAS 284668-56-0
1-(4-Chlorophenyl)-2-((5-(2-chlorophenyl)-1,3,4-oxadiazol-2-yl)thio)ethanone
CAS 284668-56-0C16H10Cl2N2O2S
1-(4-Nitrophenyl)-2-((5-(m-tolyl)-1,3,4-oxadiazol-2-yl)thio)ethanone chemical structure, C17H13N3O4S, CAS 332159-51-0
1-(4-Nitrophenyl)-2-((5-(m-tolyl)-1,3,4-oxadiazol-2-yl)thio)ethanone
CAS 332159-51-0C17H13N3O4S
1-(4-Nitrophenyl)-2-((5-(o-tolyl)-1,3,4-oxadiazol-2-yl)thio)ethanone chemical structure, C17H13N3O4S, CAS 332357-67-2
1-(4-Nitrophenyl)-2-((5-(o-tolyl)-1,3,4-oxadiazol-2-yl)thio)ethanone
CAS 332357-67-2C17H13N3O4S
1-(2,5-Dimethoxyphenyl)-2-{[5-(3-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}ethan-1-one chemical structure, C18H15FN2O4S, CAS 459845-67-1
1-(2,5-Dimethoxyphenyl)-2-{[5-(3-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}ethan-1-one
CAS 459845-67-1C18H15FN2O4S
2-[[5-(3-Bromophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-1-(4-ethylphenyl)ethanone chemical structure, C18H15BrN2O2S, CAS 312289-20-6
2-[[5-(3-Bromophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-1-(4-ethylphenyl)ethanone
CAS 312289-20-6C18H15BrN2O2S
2-{[5-(3,5-Dimethoxyphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-1-phenylethan-1-one chemical structure, C18H16N2O4S, CAS 713087-09-3
2-{[5-(3,5-Dimethoxyphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-1-phenylethan-1-one
CAS 713087-09-3C18H16N2O4S
2-[[5-(2-Methoxyphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-1-(4-nitrophenyl)ethanone chemical structure, C17H13N3O5S, CAS 825596-41-6
2-[[5-(2-Methoxyphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-1-(4-nitrophenyl)ethanone
CAS 825596-41-6C17H13N3O5S
2-[[5-(4-Chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-1-(2,5-dimethylphenyl)ethanone chemical structure, C18H15ClN2O2S, CAS 825596-43-8
2-[[5-(4-Chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-1-(2,5-dimethylphenyl)ethanone
CAS 825596-43-8C18H15ClN2O2S
N-[4-[2-[[5-(2-Chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetyl]phenyl]acetamide chemical structure, C18H14ClN3O3S, CAS 713106-58-2
N-[4-[2-[[5-(2-Chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetyl]phenyl]acetamide
CAS 713106-58-2C18H14ClN3O3S
N-[4-[2-[[5-(3-Bromophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetyl]phenyl]acetamide chemical structure, C18H14BrN3O3S, CAS 713106-59-3
N-[4-[2-[[5-(3-Bromophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetyl]phenyl]acetamide
CAS 713106-59-3C18H14BrN3O3S