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Murcko scaffold

2-Phenyl-N-(4-phenyl-1,3-thiazol-2-yl)acetamide scaffold

182 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
182
With full pages
15
Scaffold SMILES

O=C(Cc1ccccc1)Nc1nc(-c2ccccc2)cs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Phenyl-N-(4-phenyl-1,3-thiazol-2-yl)acetamide page
Murcko scaffold O=C(Cc1ccccc1)Nc1nc(-c2ccccc2)cs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 182 chemicals

2-Phenyl-N-(4-phenyl-1,3-thiazol-2-yl)acetamide chemical structure, C17H14N2OS, CAS 205928-24-1
2-Phenyl-N-(4-phenyl-1,3-thiazol-2-yl)acetamide
CAS 205928-24-1C17H14N2OS
2-(4-Fluorophenyl)-N-(4-phenyl-1,3-thiazol-2-yl)acetamide chemical structure, C17H13FN2OS, CAS 432533-45-4
2-(4-Fluorophenyl)-N-(4-phenyl-1,3-thiazol-2-yl)acetamide
CAS 432533-45-4C17H13FN2OS
2-(4-Chlorophenyl)-N-(4-phenyl-1,3-thiazol-2-yl)acetamide chemical structure, C17H13ClN2OS, CAS 518993-08-3
2-(4-Chlorophenyl)-N-(4-phenyl-1,3-thiazol-2-yl)acetamide
CAS 518993-08-3C17H13ClN2OS
2-(4-Chlorophenyl)-N-(5-methyl-4-phenyl-1,3-thiazol-2-yl)acetamide chemical structure, C18H15ClN2OS, CAS 541535-94-8
2-(4-Chlorophenyl)-N-(5-methyl-4-phenyl-1,3-thiazol-2-yl)acetamide
CAS 541535-94-8C18H15ClN2OS
N-(5-Ethyl-4-phenyl-1,3-thiazol-2-yl)-2-(4-methylphenyl)acetamide chemical structure, C20H20N2OS, CAS 587844-21-1
N-(5-Ethyl-4-phenyl-1,3-thiazol-2-yl)-2-(4-methylphenyl)acetamide
CAS 587844-21-1C20H20N2OS
2-(4-Chlorophenyl)-N-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]acetamide chemical structure, C17H12ClFN2OS, CAS 557776-40-6
2-(4-Chlorophenyl)-N-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]acetamide
CAS 557776-40-6C17H12ClFN2OS
2-(2-Chloro-6-fluorophenyl)-N-(4-phenyl-1,3-thiazol-2-yl)acetamide chemical structure, C17H12ClFN2OS, CAS 710988-98-0
2-(2-Chloro-6-fluorophenyl)-N-(4-phenyl-1,3-thiazol-2-yl)acetamide
CAS 710988-98-0C17H12ClFN2OS
N-(5-Methyl-4-phenyl-1,3-thiazol-2-yl)-2-(4-nitrophenyl)acetamide chemical structure, C18H15N3O3S, CAS 545367-33-7
N-(5-Methyl-4-phenyl-1,3-thiazol-2-yl)-2-(4-nitrophenyl)acetamide
CAS 545367-33-7C18H15N3O3S
N-[4-(4-Ethylphenyl)-1,3-thiazol-2-yl]-2-(4-nitrophenyl)acetamide chemical structure, C19H17N3O3S, CAS 545441-90-5
N-[4-(4-Ethylphenyl)-1,3-thiazol-2-yl]-2-(4-nitrophenyl)acetamide
CAS 545441-90-5C19H17N3O3S
2-(3,4-Dimethoxyphenyl)-N-(5-methyl-4-phenyl-1,3-thiazol-2-yl)acetamide chemical structure, C20H20N2O3S, CAS 495386-69-1
2-(3,4-Dimethoxyphenyl)-N-(5-methyl-4-phenyl-1,3-thiazol-2-yl)acetamide
CAS 495386-69-1C20H20N2O3S
2-(4-Bromophenyl)-N-[4-(2,4-dimethylphenyl)-1,3-thiazol-2-yl]acetamide chemical structure, C19H17BrN2OS, CAS 514818-46-3
2-(4-Bromophenyl)-N-[4-(2,4-dimethylphenyl)-1,3-thiazol-2-yl]acetamide
CAS 514818-46-3C19H17BrN2OS
2-(2-Nitrophenyl)-N-(4-phenyl-1,3-thiazol-2-yl)acetamide chemical structure, C17H13N3O3S, CAS 667408-31-3
2-(2-Nitrophenyl)-N-(4-phenyl-1,3-thiazol-2-yl)acetamide
CAS 667408-31-3C17H13N3O3S
N-(4-(4-Methoxyphenyl)thiazol-2-yl)-2-phenylacetamide chemical structure, C18H16N2O2S, CAS 333436-43-4
N-(4-(4-Methoxyphenyl)thiazol-2-yl)-2-phenylacetamide
CAS 333436-43-4C18H16N2O2S
N-[4-(3-Bromo-4-methoxyphenyl)-1,3-thiazol-2-yl]-2-phenylacetamide chemical structure, C18H15BrN2O2S, CAS 354156-81-3
N-[4-(3-Bromo-4-methoxyphenyl)-1,3-thiazol-2-yl]-2-phenylacetamide
CAS 354156-81-3C18H15BrN2O2S
2-(4-Chlorophenyl)-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]acetamide chemical structure, C17H12ClN3O3S, CAS 495377-81-6
2-(4-Chlorophenyl)-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]acetamide
CAS 495377-81-6C17H12ClN3O3S
2-(2-Chloro-6-fluorophenyl)-N-(5-ethyl-4-phenyl-1,3-thiazol-2-yl)acetamide chemical structure, C19H16ClFN2OS, CAS 710989-32-5
2-(2-Chloro-6-fluorophenyl)-N-(5-ethyl-4-phenyl-1,3-thiazol-2-yl)acetamide
CAS 710989-32-5C19H16ClFN2OS
N-[4-(4-Ethylphenyl)-1,3-thiazol-2-yl]-2-(4-methoxyphenyl)acetamide chemical structure, C20H20N2O2S, CAS 547704-16-5
N-[4-(4-Ethylphenyl)-1,3-thiazol-2-yl]-2-(4-methoxyphenyl)acetamide
CAS 547704-16-5C20H20N2O2S
N-(5-Ethyl-4-phenyl-1,3-thiazol-2-yl)-2-(2-nitrophenyl)acetamide chemical structure, C19H17N3O3S, CAS 600132-38-5
N-(5-Ethyl-4-phenyl-1,3-thiazol-2-yl)-2-(2-nitrophenyl)acetamide
CAS 600132-38-5C19H17N3O3S
2-(4-Bromophenyl)-N-(4-phenyl-1,3-thiazol-2-yl)acetamide chemical structure, C17H13BrN2OS, CAS 432531-70-9
2-(4-Bromophenyl)-N-(4-phenyl-1,3-thiazol-2-yl)acetamide
CAS 432531-70-9C17H13BrN2OS
N-[4-(4-Bromophenyl)-1,3-thiazol-2-yl]-2-(4-chlorophenyl)acetamide chemical structure, C17H12BrClN2OS, CAS 433967-00-1
N-[4-(4-Bromophenyl)-1,3-thiazol-2-yl]-2-(4-chlorophenyl)acetamide
CAS 433967-00-1C17H12BrClN2OS
N-[4-(3,4-Dimethoxyphenyl)-1,3-thiazol-2-yl]-2-phenylacetamide chemical structure, C19H18N2O3S, CAS 476210-62-5
N-[4-(3,4-Dimethoxyphenyl)-1,3-thiazol-2-yl]-2-phenylacetamide
CAS 476210-62-5C19H18N2O3S
N-[4-(3,4-Difluorophenyl)-1,3-thiazol-2-yl]-2-(3-methoxyphenyl)acetamide chemical structure, C18H14F2N2O2S, CAS 784158-80-1
N-[4-(3,4-Difluorophenyl)-1,3-thiazol-2-yl]-2-(3-methoxyphenyl)acetamide
CAS 784158-80-1C18H14F2N2O2S
2-(4-Methylphenyl)-N-(4-phenyl-1,3-thiazol-2-yl)acetamide chemical structure, C18H16N2OS, CAS 587843-98-9
2-(4-Methylphenyl)-N-(4-phenyl-1,3-thiazol-2-yl)acetamide
CAS 587843-98-9C18H16N2OS
N-(4-(4-Bromophenyl)thiazol-2-yl)-2-phenylacetamide chemical structure, C17H13BrN2OS, CAS 299405-68-8
N-(4-(4-Bromophenyl)thiazol-2-yl)-2-phenylacetamide
CAS 299405-68-8C17H13BrN2OS