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Murcko scaffold

Ring system with 3 rings and 21 atoms

95 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
95
With full pages
17
Scaffold SMILES

O=C(C=Cc1ccc(-c2ccccc2)o1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(C=Cc1ccc(-c2ccccc2)o1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 95 chemicals

1-[3-(Trifluoromethoxy)phenyl]-3-[5-[2-(trifluoromethoxy)phenyl]-2-furanyl]-2-propen-1-one chemical structure, C21H12F6O4, CAS 259196-58-2
1-[3-(Trifluoromethoxy)phenyl]-3-[5-[2-(trifluoromethoxy)phenyl]-2-furanyl]-2-propen-1-one
CAS 259196-58-2C21H12F6O4
Methyl 3-benzoyl-4-[5-(2-nitrophenyl)furan-2-yl]-2-oxobut-3-enoate chemical structure, C22H15NO7, CAS 302821-53-0
Methyl 3-benzoyl-4-[5-(2-nitrophenyl)furan-2-yl]-2-oxobut-3-enoate
CAS 302821-53-0C22H15NO7
(E)-3-[5-(3-Nitrophenyl)furan-2-yl]-1-phenylprop-2-en-1-one chemical structure, C19H13NO4, CAS 40941-02-4
(E)-3-[5-(3-Nitrophenyl)furan-2-yl]-1-phenylprop-2-en-1-one
CAS 40941-02-4C19H13NO4
(E)-3-[5-(2-Nitrophenyl)furan-2-yl]-1-phenylprop-2-en-1-one chemical structure, C19H13NO4, CAS 5530-39-2
(E)-3-[5-(2-Nitrophenyl)furan-2-yl]-1-phenylprop-2-en-1-one
CAS 5530-39-2C19H13NO4
(2E)-3-[5-(4-Bromophenyl)furan-2-yl]-1-phenylprop-2-en-1-one chemical structure, C19H13BrO2, CAS 20005-40-7
(2E)-3-[5-(4-Bromophenyl)furan-2-yl]-1-phenylprop-2-en-1-one
CAS 20005-40-7C19H13BrO2
(E)-3-(5-(2,5-Dichlorophenyl)furan-2-yl)-1-(4-methoxyphenyl)prop-2-en-1-one chemical structure, C20H14Cl2O3, CAS 688362-95-0
(E)-3-(5-(2,5-Dichlorophenyl)furan-2-yl)-1-(4-methoxyphenyl)prop-2-en-1-one
CAS 688362-95-0C20H14Cl2O3
3-(5-(2,3-Dichlorophenyl)-2-furyl)-1-(4-methoxyphenyl)-2-propen-1-one chemical structure, C20H14Cl2O3, CAS 304896-55-7
3-(5-(2,3-Dichlorophenyl)-2-furyl)-1-(4-methoxyphenyl)-2-propen-1-one
CAS 304896-55-7C20H14Cl2O3
(E)-1-(4-Methoxyphenyl)-3-(5-(3-(trifluoromethyl)phenyl)furan-2-yl)prop-2-en-1-one chemical structure, C21H15F3O3, CAS 304896-52-4
(E)-1-(4-Methoxyphenyl)-3-(5-(3-(trifluoromethyl)phenyl)furan-2-yl)prop-2-en-1-one
CAS 304896-52-4C21H15F3O3
(E)-3-[5-(3-Chlorophenyl)furan-2-yl]-1-(4-methoxyphenyl)prop-2-en-1-one chemical structure, C20H15ClO3, CAS 304896-53-5
(E)-3-[5-(3-Chlorophenyl)furan-2-yl]-1-(4-methoxyphenyl)prop-2-en-1-one
CAS 304896-53-5C20H15ClO3
(E)-1-(4-Methoxyphenyl)-3-[5-(4-nitrophenyl)furan-2-yl]prop-2-en-1-one chemical structure, C20H15NO5, CAS 688362-97-2
(E)-1-(4-Methoxyphenyl)-3-[5-(4-nitrophenyl)furan-2-yl]prop-2-en-1-one
CAS 688362-97-2C20H15NO5
3-(5-(4-Methoxyphenyl)-2-furyl)-1-(4-methylphenyl)-2-propen-1-one chemical structure, C21H18O3, CAS 5528-80-3
3-(5-(4-Methoxyphenyl)-2-furyl)-1-(4-methylphenyl)-2-propen-1-one
CAS 5528-80-3C21H18O3
1-(4-Chlorophenyl)-3-(5-(2-nitrophenyl)-2-furyl)-2-propen-1-one chemical structure, C19H12ClNO4, CAS 299954-35-1
1-(4-Chlorophenyl)-3-(5-(2-nitrophenyl)-2-furyl)-2-propen-1-one
CAS 299954-35-1C19H12ClNO4
(E)-1-(4-Methylphenyl)-3-[5-(2-nitrophenyl)furan-2-yl]prop-2-en-1-one chemical structure, C20H15NO4, CAS 1164473-85-1
(E)-1-(4-Methylphenyl)-3-[5-(2-nitrophenyl)furan-2-yl]prop-2-en-1-one
CAS 1164473-85-1C20H15NO4
(E)-1-(4-Chlorophenyl)-3-[5-(4-methoxyphenyl)furan-2-yl]prop-2-en-1-one chemical structure, C20H15ClO3, CAS 1422034-10-3
(E)-1-(4-Chlorophenyl)-3-[5-(4-methoxyphenyl)furan-2-yl]prop-2-en-1-one
CAS 1422034-10-3C20H15ClO3
(E)-1-(4-Methoxyphenyl)-3-[5-(2-nitrophenyl)furan-2-yl]prop-2-en-1-one chemical structure, C20H15NO5, CAS 688362-88-1
(E)-1-(4-Methoxyphenyl)-3-[5-(2-nitrophenyl)furan-2-yl]prop-2-en-1-one
CAS 688362-88-1C20H15NO5
(2E)-3-[5-(2-Chlorophenyl)-2-furyl]-1-(4-fluorophenyl)prop-2-en-1-one chemical structure, C19H12ClFO2, CAS 5538-91-0
(2E)-3-[5-(2-Chlorophenyl)-2-furyl]-1-(4-fluorophenyl)prop-2-en-1-one
CAS 5538-91-0C19H12ClFO2
(E)-1-(4-Fluorophenyl)-3-[5-(2-nitrophenyl)furan-2-yl]prop-2-en-1-one chemical structure, C19H12FNO4, CAS 1164489-14-8
(E)-1-(4-Fluorophenyl)-3-[5-(2-nitrophenyl)furan-2-yl]prop-2-en-1-one
CAS 1164489-14-8C19H12FNO4
(E)-1-(4-Fluorophenyl)-3-(5-phenylfuran-2-yl)prop-2-en-1-one chemical structure, C19H13FO2, CAS 301227-56-5
(E)-1-(4-Fluorophenyl)-3-(5-phenylfuran-2-yl)prop-2-en-1-one
CAS 301227-56-5C19H13FO2
1-(4-Fluorophenyl)-3-[5-(3-nitrophenyl)-2-furyl]prop-2-en-1-one chemical structure, C19H12FNO4, CAS 5554-93-8
1-(4-Fluorophenyl)-3-[5-(3-nitrophenyl)-2-furyl]prop-2-en-1-one
CAS 5554-93-8C19H12FNO4
(E)-1-(4-Methoxyphenyl)-3-[5-(3-nitrophenyl)furan-2-yl]prop-2-en-1-one chemical structure, C20H15NO5, CAS 688362-90-5
(E)-1-(4-Methoxyphenyl)-3-[5-(3-nitrophenyl)furan-2-yl]prop-2-en-1-one
CAS 688362-90-5C20H15NO5
(2E)-3-[5-(4-Chlorophenyl)furan-2-yl]-1-phenylprop-2-en-1-one chemical structure, C19H13ClO2, CAS 20005-39-4
(2E)-3-[5-(4-Chlorophenyl)furan-2-yl]-1-phenylprop-2-en-1-one
CAS 20005-39-4C19H13ClO2
(E)-3-[5-(2,5-Dichlorophenyl)furan-2-yl]-1-(4-nitrophenyl)prop-2-en-1-one chemical structure, C19H11Cl2NO4, CAS 5771-78-8
(E)-3-[5-(2,5-Dichlorophenyl)furan-2-yl]-1-(4-nitrophenyl)prop-2-en-1-one
CAS 5771-78-8C19H11Cl2NO4
(E)-3-[5-(2,5-Dichlorophenyl)furan-2-yl]-1-(4-fluorophenyl)prop-2-en-1-one chemical structure, C19H11Cl2FO2, CAS 301312-54-9
(E)-3-[5-(2,5-Dichlorophenyl)furan-2-yl]-1-(4-fluorophenyl)prop-2-en-1-one
CAS 301312-54-9C19H11Cl2FO2
1-(4-Fluorophenyl)-3-(5-(3-(trifluoromethyl)phenyl)-2-furyl)-2-propen-1-one chemical structure, C20H12F4O2, CAS 304896-59-1
1-(4-Fluorophenyl)-3-(5-(3-(trifluoromethyl)phenyl)-2-furyl)-2-propen-1-one
CAS 304896-59-1C20H12F4O2