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Murcko scaffold

N-(Benzylideneamino)-4-phenyl-1,3-thiazol-2-amine scaffold

81 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
81
With full pages
12
Scaffold SMILES

C(=NNc1nc(-c2ccccc2)cs1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-(Benzylideneamino)-4-phenyl-1,3-thiazol-2-amine page
Murcko scaffold C(=NNc1nc(-c2ccccc2)cs1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 81 chemicals

N-[(4-Fluorophenyl)methylideneamino]-4-phenyl-1,3-thiazol-2-amine chemical structure, C16H12FN3S, CAS 342784-53-6
N-[(4-Fluorophenyl)methylideneamino]-4-phenyl-1,3-thiazol-2-amine
CAS 342784-53-6C16H12FN3S
4-(4-Fluorophenyl)-N-[(4-methoxyphenyl)methylideneamino]-1,3-thiazol-2-amine chemical structure, C17H14FN3OS, CAS 5780-59-6
4-(4-Fluorophenyl)-N-[(4-methoxyphenyl)methylideneamino]-1,3-thiazol-2-amine
CAS 5780-59-6C17H14FN3OS
Benzaldehyde 2-[4-(4-chlorophenyl)-2-thiazolyl]hydrazone chemical structure, C16H12ClN3S, CAS 306280-32-0
Benzaldehyde 2-[4-(4-chlorophenyl)-2-thiazolyl]hydrazone
CAS 306280-32-0C16H12ClN3S
N-(Benzylideneamino)-4-phenyl-1,3-thiazol-2-amine chemical structure, C16H13N3S, CAS 4216-52-8
N-(Benzylideneamino)-4-phenyl-1,3-thiazol-2-amine
CAS 4216-52-8C16H13N3S
Benzaldehyde 2-[4-(4-bromophenyl)-2-thiazolyl]hydrazone chemical structure, C16H12BrN3S, CAS 4871-24-3
Benzaldehyde 2-[4-(4-bromophenyl)-2-thiazolyl]hydrazone
CAS 4871-24-3C16H12BrN3S
4-Methylbenzaldehyde 2-[4-(4-chlorophenyl)-3-methyl-2(3H)-thiazolylidene]hydrazone chemical structure, C18H16ClN3S, CAS 674810-97-0
4-Methylbenzaldehyde 2-[4-(4-chlorophenyl)-3-methyl-2(3H)-thiazolylidene]hydrazone
CAS 674810-97-0C18H16ClN3S
2-(2-Propen-1-yloxy)benzaldehyde 2-[4-(2,4-dichlorophenyl)-2-thiazolyl]hydrazone chemical structure, C19H15Cl2N3OS, CAS 552854-68-9
2-(2-Propen-1-yloxy)benzaldehyde 2-[4-(2,4-dichlorophenyl)-2-thiazolyl]hydrazone
CAS 552854-68-9C19H15Cl2N3OS
4-[2-[2-[(4-tert-Butylphenyl)methylidene]hydrazinyl]-1,3-thiazol-4-yl]-N,N-diethylbenzenesulfonamide chemical structure, C24H30N4O2S2, CAS 7027-09-0
4-[2-[2-[(4-tert-Butylphenyl)methylidene]hydrazinyl]-1,3-thiazol-4-yl]-N,N-diethylbenzenesulfonamide
CAS 7027-09-0C24H30N4O2S2
4-(4-Chlorophenyl)-N-[(4-dimethylaminophenyl)methylideneamino]-1,3-thiazol-2-amine chemical structure, C18H17ClN4S, CAS 7027-10-3
4-(4-Chlorophenyl)-N-[(4-dimethylaminophenyl)methylideneamino]-1,3-thiazol-2-amine
CAS 7027-10-3C18H17ClN4S
N-[(2,4-Dichlorophenyl)methylideneamino]-4-phenyl-1,3-thiazol-2-amine chemical structure, C16H11Cl2N3S, CAS 339284-43-4
N-[(2,4-Dichlorophenyl)methylideneamino]-4-phenyl-1,3-thiazol-2-amine
CAS 339284-43-4C16H11Cl2N3S
Methyl 4-{(E)-[2-(4-phenyl-1,3-thiazol-2-yl)hydrazinylidene]methyl}benzoate chemical structure, C18H15N3O2S, CAS 5186-15-2
Methyl 4-{(E)-[2-(4-phenyl-1,3-thiazol-2-yl)hydrazinylidene]methyl}benzoate
CAS 5186-15-2C18H15N3O2S
N-[(E)-Benzylideneamino]-4-phenyl-1,3-thiazol-2-amine chemical structure, C16H13N3S, CAS 1049976-68-2
N-[(E)-Benzylideneamino]-4-phenyl-1,3-thiazol-2-amine
CAS 1049976-68-2C16H13N3S
N-[(E)-(4-Bromophenyl)methylideneamino]-4-phenyl-1,3-thiazol-2-amine chemical structure, C16H12BrN3S, CAS 1322209-67-5
N-[(E)-(4-Bromophenyl)methylideneamino]-4-phenyl-1,3-thiazol-2-amine
CAS 1322209-67-5C16H12BrN3S
4-(4-Methylphenyl)-N-[(E)-(4-methylphenyl)methylideneamino]-1,3-thiazol-2-amine chemical structure, C18H17N3S, CAS 351444-10-5
4-(4-Methylphenyl)-N-[(E)-(4-methylphenyl)methylideneamino]-1,3-thiazol-2-amine
CAS 351444-10-5C18H17N3S
4-Bromobenzaldehyde [4-(4-methylphenyl)-1,3-thiazol-2-yl]hydrazone chemical structure, C17H14BrN3S, CAS 1322209-21-1
4-Bromobenzaldehyde [4-(4-methylphenyl)-1,3-thiazol-2-yl]hydrazone
CAS 1322209-21-1C17H14BrN3S
(1E)-1-(4-Methylphenyl)ethanone [4-(4-methylphenyl)-1,3-thiazol-2-yl]hydrazone chemical structure, C19H19N3S, CAS 36941-31-8
(1E)-1-(4-Methylphenyl)ethanone [4-(4-methylphenyl)-1,3-thiazol-2-yl]hydrazone
CAS 36941-31-8C19H19N3S
(E)-4-Phenyl-2-(2-(1-phenylethylidene)hydrazinyl)thiazole chemical structure, C17H15N3S, CAS 1502825-86-6
(E)-4-Phenyl-2-(2-(1-phenylethylidene)hydrazinyl)thiazole
CAS 1502825-86-6C17H15N3S
(E)-Methyl 4-((2-(4-(p-tolyl)thiazol-2-yl)hydrazono)methyl)benzoate chemical structure, C19H17N3O2S, CAS 351444-13-8
(E)-Methyl 4-((2-(4-(p-tolyl)thiazol-2-yl)hydrazono)methyl)benzoate
CAS 351444-13-8C19H17N3O2S
4-(4-Chlorophenyl)-N-[(E)-(3,4-dimethoxyphenyl)methylideneamino]-1,3-thiazol-2-amine chemical structure, C18H16ClN3O2S, CAS 302571-37-5
4-(4-Chlorophenyl)-N-[(E)-(3,4-dimethoxyphenyl)methylideneamino]-1,3-thiazol-2-amine
CAS 302571-37-5C18H16ClN3O2S
4-Phenyl-N-[(E)-(4-propan-2-ylphenyl)methylideneamino]-1,3-thiazol-2-amine chemical structure, C19H19N3S, CAS 5852-77-7
4-Phenyl-N-[(E)-(4-propan-2-ylphenyl)methylideneamino]-1,3-thiazol-2-amine
CAS 5852-77-7C19H19N3S
3-[(E)-[[4-(4-Bromophenyl)-1,3-thiazol-2-yl]hydrazinylidene]methyl]phenol chemical structure, C16H12BrN3OS, CAS 154694-10-7
3-[(E)-[[4-(4-Bromophenyl)-1,3-thiazol-2-yl]hydrazinylidene]methyl]phenol
CAS 154694-10-7C16H12BrN3OS
(Z)-4-(4-Bromophenyl)-2-(2-(1-phenylethylidene)hydrazinyl)thiazole chemical structure, C17H14BrN3S, CAS 37053-60-4
(Z)-4-(4-Bromophenyl)-2-(2-(1-phenylethylidene)hydrazinyl)thiazole
CAS 37053-60-4C17H14BrN3S
1-(4-Methoxyphenyl)ethanone [4-(4-chlorophenyl)-1,3-thiazol-2-yl]hydrazone chemical structure, C18H16ClN3OS, CAS 1686128-01-7
1-(4-Methoxyphenyl)ethanone [4-(4-chlorophenyl)-1,3-thiazol-2-yl]hydrazone
CAS 1686128-01-7C18H16ClN3OS
N-[(E)-Benzylideneamino]-4-(4-nitrophenyl)-1,3-thiazol-2-amine chemical structure, C16H12N4O2S, CAS 324066-16-2
N-[(E)-Benzylideneamino]-4-(4-nitrophenyl)-1,3-thiazol-2-amine
CAS 324066-16-2C16H12N4O2S