CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 22 atoms

14 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
14
With full pages
11
Scaffold SMILES

O=C(Nc1ccccc1)Nc1c[nH]n(-c2ccccc2)c1=O

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)Nc1c[nH]n(-c2ccccc2)c1=O

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

3-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-1-(4-fluorophenyl)urea chemical structure, C18H17FN4O2, CAS 333326-26-4
3-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-1-(4-fluorophenyl)urea
CAS 333326-26-4C18H17FN4O2
3-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-1-[3-(trifluoromethyl)phenyl]urea chemical structure, C19H17F3N4O2, CAS 501685-13-8
3-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-1-[3-(trifluoromethyl)phenyl]urea
CAS 501685-13-8C19H17F3N4O2
N-(5-Chloro-2,4-dimethoxyphenyl)-N'-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)urea chemical structure, C20H21ClN4O4, CAS 501925-35-5
N-(5-Chloro-2,4-dimethoxyphenyl)-N'-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)urea
CAS 501925-35-5C20H21ClN4O4
1-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-3-phenylurea chemical structure, C18H18N4O2, CAS 51944-15-1
1-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-3-phenylurea
CAS 51944-15-1C18H18N4O2
1-(1,5-Dimethyl-3-oxo-2-phenylpyrazol-4-yl)-3-(3-methylphenyl)urea chemical structure, C19H20N4O2, CAS 293329-74-5
1-(1,5-Dimethyl-3-oxo-2-phenylpyrazol-4-yl)-3-(3-methylphenyl)urea
CAS 293329-74-5C19H20N4O2
1-(1,5-Dimethyl-3-oxo-2-phenylpyrazol-4-yl)-3-(4-methylphenyl)urea chemical structure, C19H20N4O2, CAS 70862-92-9
1-(1,5-Dimethyl-3-oxo-2-phenylpyrazol-4-yl)-3-(4-methylphenyl)urea
CAS 70862-92-9C19H20N4O2
1-(3,4-Dichlorophenyl)-3-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)urea chemical structure, C18H16Cl2N4O2, CAS 313274-32-7
1-(3,4-Dichlorophenyl)-3-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)urea
CAS 313274-32-7C18H16Cl2N4O2
1-(3-Chlorophenyl)-3-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)urea chemical structure, C18H17ClN4O2, CAS 325850-26-8
1-(3-Chlorophenyl)-3-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)urea
CAS 325850-26-8C18H17ClN4O2
RefChem:381602 chemical structure, C18H15ClF2N4O2, CAS 5926-31-8
RefChem:381602
CAS 5926-31-8C18H15ClF2N4O2
N-(4-Chlorophenyl)-N'-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)urea chemical structure, C18H17ClN4O2, CAS 5525-35-9
N-(4-Chlorophenyl)-N'-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)urea
CAS 5525-35-9C18H17ClN4O2
N'-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-N-methyl-N-phenylurea chemical structure, C19H20N4O2, CAS 691388-14-4
N'-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-N-methyl-N-phenylurea
CAS 691388-14-4C19H20N4O2
1-(1,5-Dimethyl-3-oxo-2-phenylpyrazol-4-yl)-3-[4-(trifluoromethoxy)phenyl]urea chemical structure, C19H17F3N4O3, CAS 946386-37-4
1-(1,5-Dimethyl-3-oxo-2-phenylpyrazol-4-yl)-3-[4-(trifluoromethoxy)phenyl]urea
CAS 946386-37-4C19H17F3N4O3
3-(4-Chlorophenyl)-1-(1-methyl-3-oxo-2-phenyl-5-propan-2-ylpyrazol-4-yl)urea chemical structure, C20H21ClN4O2, CAS 903895-98-7
3-(4-Chlorophenyl)-1-(1-methyl-3-oxo-2-phenyl-5-propan-2-ylpyrazol-4-yl)urea
CAS 903895-98-7C20H21ClN4O2
1-(2-Chlorophenyl)-3-[1-methyl-5-(1-methylethyl)-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl]urea chemical structure, C20H21ClN4O2, CAS 903896-00-4
1-(2-Chlorophenyl)-3-[1-methyl-5-(1-methylethyl)-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl]urea
CAS 903896-00-4C20H21ClN4O2