Murcko scaffold
Cyclohexanone scaffold
2,699 chemicals on CompoundList share this ring system.
- Rings
- 1
- Scaffold atoms
- 7
- Chemicals
- 2,699
- With full pages
- 295
Scaffold SMILES
O=C1CCCCC1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1,249 to 1,296 of 2,699 chemicals
2,2,3-Trichlorocyclohexan-1-one
CAS 58965-61-0C6H7Cl3O
trans-(+/-)-3,5-Dihydroxy-cyclohexanone
CAS 165523-04-6C6H10O3
5-tert-Butyl-2-oxocyclohexane-1-carbaldehyde
CAS 64798-94-3C11H18O2
2-Oxocyclohexane-1-sulfonyl chloride
CAS 1020842-00-5C6H9ClO3S
![tert-Butyl N-[(2-oxocyclohexyl)methyl]carbamate chemical structure, C12H21NO3, CAS 477584-15-9](/s/URNWDOSTYDPAKR-UHFFFAOYSA-N.svg)
tert-Butyl N-[(2-oxocyclohexyl)methyl]carbamate
CAS 477584-15-9C12H21NO3
4-(2-Aminoethyl)cyclohexan-1-one
CAS 910405-56-0C8H15NO
4-(Aminomethyl)cyclohexanone
CAS 934475-93-1C7H13NO
4-Oxocyclohexane-1-sulfonyl chloride
CAS 1262409-43-7C6H9ClO3S
3-Oxocyclohexane-1-carboxamide
CAS 1140815-79-7C7H11NO2
3-(Methylamino)cyclohexan-1-one
CAS 1314921-51-1C7H13NO
2-Cyano-4,4-difluorocyclohexanone
CAS 1309602-28-5C7H7F2NO
2-Hydroxy-5,5-dimethylcyclohexan-1-one
CAS 412016-69-4C8H14O2
2-(1-Hydroxypropan-2-yl)-5-methylcyclohexan-1-one
CAS 623531-70-4C10H18O2
Methyl 1-((tert-butoxycarbonyl)amino)-4-oxocyclohexanecarboxylate
CAS 191111-27-0C13H21NO5
5,5-Dimethyl-2-oxocyclohexyl acetate
CAS 61592-52-7C10H16O3
3-Butyl-4,4-dimethylcyclohexan-1-one
CAS 109539-15-3C12H22O
2,6-Dihydroxycyclohexan-1-one
CAS 823179-28-8C6H10O3
![Ethyl [(1S)-1-ethyl-2-oxocyclohexyl]acetate chemical structure, C12H20O3, CAS 831170-22-0](/s/ITJZGLUFLRKWTN-LBPRGKRZSA-N.svg)
Ethyl [(1S)-1-ethyl-2-oxocyclohexyl]acetate
CAS 831170-22-0C12H20O3
![3-[(1R,4S)-4-Ethoxy-2-oxocyclohexyl]propanoic acid chemical structure, C11H18O4, CAS 180413-78-9](/s/HTHZXAIDCJAUMF-BDAKNGLRSA-N.svg)
3-[(1R,4S)-4-Ethoxy-2-oxocyclohexyl]propanoic acid
CAS 180413-78-9C11H18O4
4-Carbethoxy-2,6-bis(trifluoroacetyl)cyclohexanone
CAS 1055414-64-6C13H12F6O5
4-tert-Butyl-2,6-bis(trifluoroacetyl)cyclohexanone
CAS 959641-28-2C14H16F6O3
4-Carboxy-2,6-bis(trifluoroacetyl)cyclohexanone
CAS 1055414-66-8C11H8F6O5
4-Methyl-2,6-bis(trifluoroacetyl)cyclohexanone
CAS 1055414-57-7C11H10F6O3
(4-Oxocyclohexyl)boronic acid
CAS 799842-98-1C6H11BO3
- Methyl 1-amino-4-oxocyclohexanecarboxylate887245-67-2C8H13NO3
- 4-Hydroxy-2-methylcyclohexanone102547-89-7C7H12O2
- 2-Hydroxy-2-(4-oxocyclohexyl)acetonitrile1822765-44-5C8H11NO2
- Ethyl 3-methyl-4-oxocyclohexane-1-carboxylate1207529-72-3C10H16O3
- 4-Methyl-4-((trimethylsilyl)ethynyl)cyclohexanone1207109-92-9C12H20OSi
- 4-(Methoxymethyl)-4-methylcyclohexanone1256546-89-0C9H16O2
- 4-(Methoxymethyl)cyclohexan-1-one17159-84-1C8H14O2
- 4-(2-Methoxyethyl)cyclohexanone165532-01-4C9H16O2
- 4-(Ethoxymethyl)cyclohexanone17159-86-3C9H16O2
- 4-(2-Propyn-1-yloxy)cyclohexanone950772-87-9C9H12O2
- 3-Hydroxy-2-methylcyclohexan-1-one102547-88-6C7H12O2
- tert-Butyl 2-(4-oxocyclohexyl)acetate956596-81-9C12H20O3
- Ethyl 1-(2-methoxyethyl)-4-oxocyclohexanecarboxylate1292278-43-3C12H20O4
- 2,2,4,4-Tetramethylcyclohexan-1-one13440-76-1C10H18O
- Cyclohexanecarboxylic acid, 2,2-dimethyl-4-oxo-, methyl ester, (1S)-1312537-12-4C10H16O3
- Methyl 2,2-dimethyl-4-oxocyclohexane-1-carboxylate1312535-32-2C10H16O3
- 4,4-Dimethyl-2-oxocyclohexanecarbaldehyde1309788-48-4C9H14O2
- Ethyl 2-(4,4-dimethyl-2-oxocyclohexyl)-2-oxoacetate412019-00-2C12H18O4
- 4-(1-Hydroxypropyl)cyclohexanone1351990-46-9C9H16O2
- 4-(1-Hydroxy-2-methylpropyl)cyclohexanone1352933-52-8C10H18O2
- 4-(1-(Dimethylamino)propyl)cyclohexanone1352934-87-2C11H21NO
- N-(1-(4-Oxocyclohexyl)propyl)methanesulfonamide1352934-92-9C10H19NO3S
- 4,4-Dimethyl-2-(2-oxopropyl)cyclohexan-1-one163128-46-9C11H18O2
- 4-Hydroxy-4-(propan-2-yl)cyclohexan-1-one32936-69-9C9H16O2
Related scaffolds
Same ring framework with different atoms or bond orders
![Scaffold O=c1cccc[nH]1](/scaffold/UBQKCCHYAOITMY-UHFFFAOYSA-N/structure.svg)
