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Murcko scaffold

N-Benzyl-2,3-dihydro-1,4-benzodioxine-6-carboxamide scaffold

8 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
8
With full pages
5
Scaffold SMILES

O=C(NCc1ccccc1)c1ccc2c(c1)OCCO2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-Benzyl-2,3-dihydro-1,4-benzodioxine-6-carboxamide page
Murcko scaffold O=C(NCc1ccccc1)c1ccc2c(c1)OCCO2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

N-Benzyl-2,3-dihydro-1,4-benzodioxine-6-carboxamide chemical structure, C16H15NO3, CAS 310453-94-2
N-Benzyl-2,3-dihydro-1,4-benzodioxine-6-carboxamide
CAS 310453-94-2C16H15NO3
N-Benzyl-N-methyl-2,3-dihydro-1,4-benzodioxine-6-carboxamide chemical structure, C17H17NO3, CAS 333749-80-7
N-Benzyl-N-methyl-2,3-dihydro-1,4-benzodioxine-6-carboxamide
CAS 333749-80-7C17H17NO3
N-(3-Chlorobenzyl)-2,3-dihydro-1,4-benzodioxine-6-carboxamide chemical structure, C16H14ClNO3, CAS 830340-16-4
N-(3-Chlorobenzyl)-2,3-dihydro-1,4-benzodioxine-6-carboxamide
CAS 830340-16-4C16H14ClNO3
Methyl 4-[(2,3-dihydro-1,4-benzodioxine-6-carbonylamino)methyl]benzoate chemical structure, C18H17NO5, CAS 725717-02-2
Methyl 4-[(2,3-dihydro-1,4-benzodioxine-6-carbonylamino)methyl]benzoate
CAS 725717-02-2C18H17NO5
2,3-Dihydro-N-[(2-methylphenyl)methyl]-1,4-benzodioxin-6-carboxamide chemical structure, C17H17NO3, CAS 923752-77-6
2,3-Dihydro-N-[(2-methylphenyl)methyl]-1,4-benzodioxin-6-carboxamide
CAS 923752-77-6C17H17NO3
N-[[3-(Trifluoromethyl)phenyl]methyl]-2,3-dihydro-1,4-benzodioxine-6-carboxamide chemical structure, C17H14F3NO3, CAS 924037-59-2
N-[[3-(Trifluoromethyl)phenyl]methyl]-2,3-dihydro-1,4-benzodioxine-6-carboxamide
CAS 924037-59-2C17H14F3NO3
2,3-Dihydro-N-[(4-methoxyphenyl)methyl]-N-methyl-1,4-benzodioxin-6-carboxamide chemical structure, C18H19NO4, CAS 1386219-74-4
2,3-Dihydro-N-[(4-methoxyphenyl)methyl]-N-methyl-1,4-benzodioxin-6-carboxamide
CAS 1386219-74-4C18H19NO4
N-Benzyl-N-(cyanomethyl)-2,3-dihydro-1,4-benzodioxine-6-carboxamide chemical structure, C18H16N2O3, CAS 1197604-89-9
N-Benzyl-N-(cyanomethyl)-2,3-dihydro-1,4-benzodioxine-6-carboxamide
CAS 1197604-89-9C18H16N2O3