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Murcko scaffold

Ring system with 3 rings and 21 atoms

18 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
18
With full pages
6
Scaffold SMILES

O=S(=O)(c1ccccc1)n1cc(Sc2ccccc2)cn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(c1ccccc1)n1cc(Sc2ccccc2)cn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 18 of 18 chemicals

1-(Benzenesulfonyl)-3,5-dimethyl-4-phenylsulfanylpyrazole chemical structure, C17H16N2O2S2, CAS 300815-80-9
1-(Benzenesulfonyl)-3,5-dimethyl-4-phenylsulfanylpyrazole
CAS 300815-80-9C17H16N2O2S2
1-(Mesitylsulfonyl)-3,5-dimethyl-4-(p-tolylthio)-1H-pyrazole chemical structure, C21H24N2O2S2, CAS 394236-70-5
1-(Mesitylsulfonyl)-3,5-dimethyl-4-(p-tolylthio)-1H-pyrazole
CAS 394236-70-5C21H24N2O2S2
1-(4-Chlorophenyl)sulfonyl-3,5-dimethyl-4-phenylsulfanylpyrazole chemical structure, C17H15ClN2O2S2, CAS 300815-73-0
1-(4-Chlorophenyl)sulfonyl-3,5-dimethyl-4-phenylsulfanylpyrazole
CAS 300815-73-0C17H15ClN2O2S2
4-((4-Chlorophenyl)thio)-3,5-dimethyl-1-tosyl-1H-pyrazole chemical structure, C18H17ClN2O2S2, CAS 394236-89-6
4-((4-Chlorophenyl)thio)-3,5-dimethyl-1-tosyl-1H-pyrazole
CAS 394236-89-6C18H17ClN2O2S2
3,5-Dimethyl-4-phenylsulfanyl-1-(2,4,6-trimethylphenyl)sulfonylpyrazole chemical structure, C20H22N2O2S2, CAS 394237-16-2
3,5-Dimethyl-4-phenylsulfanyl-1-(2,4,6-trimethylphenyl)sulfonylpyrazole
CAS 394237-16-2C20H22N2O2S2
4-((4-Chlorophenyl)thio)-3,5-dimethyl-1-((4-nitrophenyl)sulfonyl)-1H-pyrazole chemical structure, C17H14ClN3O4S2, CAS 394236-87-4
4-((4-Chlorophenyl)thio)-3,5-dimethyl-1-((4-nitrophenyl)sulfonyl)-1H-pyrazole
CAS 394236-87-4C17H14ClN3O4S2
3,5-Dimethyl-1-((4-nitrophenyl)sulfonyl)-4-(phenylthio)-1H-pyrazole chemical structure, C17H15N3O4S2, CAS 303792-17-8
3,5-Dimethyl-1-((4-nitrophenyl)sulfonyl)-4-(phenylthio)-1H-pyrazole
CAS 303792-17-8C17H15N3O4S2
4-((4-Chlorophenyl)thio)-1-((4-fluorophenyl)sulfonyl)-3,5-dimethyl-1H-pyrazole chemical structure, C17H14ClFN2O2S2, CAS 433963-61-2
4-((4-Chlorophenyl)thio)-1-((4-fluorophenyl)sulfonyl)-3,5-dimethyl-1H-pyrazole
CAS 433963-61-2C17H14ClFN2O2S2
1-(4-Methoxyphenyl)sulfonyl-3,5-dimethyl-4-(4-nitrophenyl)sulfanylpyrazole chemical structure, C18H17N3O5S2, CAS 300379-13-9
1-(4-Methoxyphenyl)sulfonyl-3,5-dimethyl-4-(4-nitrophenyl)sulfanylpyrazole
CAS 300379-13-9C18H17N3O5S2
3,5-Dimethyl-1-(2-nitro-benzenesulfonyl)-4-phenylsulfanyl-1H-pyrazole chemical structure, C17H15N3O4S2, CAS 302582-55-4
3,5-Dimethyl-1-(2-nitro-benzenesulfonyl)-4-phenylsulfanyl-1H-pyrazole
CAS 302582-55-4C17H15N3O4S2
1-((4-Fluorophenyl)sulfonyl)-3,5-dimethyl-4-(p-tolylthio)-1H-pyrazole chemical structure, C18H17FN2O2S2, CAS 433687-82-2
1-((4-Fluorophenyl)sulfonyl)-3,5-dimethyl-4-(p-tolylthio)-1H-pyrazole
CAS 433687-82-2C18H17FN2O2S2
3,5-Dimethyl-4-(phenylthio)-1-((2,4,6-triisopropylphenyl)sulfonyl)-1H-pyrazole chemical structure, C26H34N2O2S2, CAS 301331-51-1
3,5-Dimethyl-4-(phenylthio)-1-((2,4,6-triisopropylphenyl)sulfonyl)-1H-pyrazole
CAS 301331-51-1C26H34N2O2S2
4-((4-Chlorophenyl)thio)-3,5-dimethyl-1-((2,4,6-triisopropylphenyl)sulfonyl)-1H-pyrazole chemical structure, C26H33ClN2O2S2, CAS 394236-98-7
4-((4-Chlorophenyl)thio)-3,5-dimethyl-1-((2,4,6-triisopropylphenyl)sulfonyl)-1H-pyrazole
CAS 394236-98-7C26H33ClN2O2S2
1-(4-Chlorophenyl)sulfonyl-3,5-dimethyl-4-(4-nitrophenyl)sulfanylpyrazole chemical structure, C17H14ClN3O4S2, CAS 391222-07-4
1-(4-Chlorophenyl)sulfonyl-3,5-dimethyl-4-(4-nitrophenyl)sulfanylpyrazole
CAS 391222-07-4C17H14ClN3O4S2
3,5-Dimethyl-4-(p-tolylthio)-1-((2,4,6-triisopropylphenyl)sulfonyl)-1H-pyrazole chemical structure, C27H36N2O2S2, CAS 394236-74-9
3,5-Dimethyl-4-(p-tolylthio)-1-((2,4,6-triisopropylphenyl)sulfonyl)-1H-pyrazole
CAS 394236-74-9C27H36N2O2S2
N-(4-((4-((4-Chlorophenyl)thio)-3,5-dimethyl-1H-pyrazol-1-yl)sulfonyl)phenyl)acetamide chemical structure, C19H18ClN3O3S2, CAS 394236-95-4
N-(4-((4-((4-Chlorophenyl)thio)-3,5-dimethyl-1H-pyrazol-1-yl)sulfonyl)phenyl)acetamide
CAS 394236-95-4C19H18ClN3O3S2
1-(4-Bromophenyl)sulfonyl-3,5-dimethyl-4-(4-nitrophenyl)sulfanylpyrazole chemical structure, C17H14BrN3O4S2, CAS 301156-82-1
1-(4-Bromophenyl)sulfonyl-3,5-dimethyl-4-(4-nitrophenyl)sulfanylpyrazole
CAS 301156-82-1C17H14BrN3O4S2
4-[(3-Chlorophenyl)thio]-3-methyl-1-[(4-methylphenyl)sulfonyl]-1H-pyrazole chemical structure, C17H15ClN2O2S2, CAS 2197053-25-9
4-[(3-Chlorophenyl)thio]-3-methyl-1-[(4-methylphenyl)sulfonyl]-1H-pyrazole
CAS 2197053-25-9C17H15ClN2O2S2