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Murcko scaffold

Ring system with 3 rings and 20 atoms

54 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
54
With full pages
10
Scaffold SMILES

O=C1C(=Cc2ccccc2)CCC1=Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1C(=Cc2ccccc2)CCC1=Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 54 chemicals

Cyclopentanone, 2,5-bis[(4-hydroxyphenyl)methylene]- chemical structure, C19H16O3, CAS 27060-66-8
Cyclopentanone, 2,5-bis[(4-hydroxyphenyl)methylene]-
CAS 27060-66-8C19H16O3
Cyclopentanone, 2,5-bis[(4-hydroxy-3,5-dimethoxyphenyl)methylene]- chemical structure, C23H24O7, CAS 56720-22-0
Cyclopentanone, 2,5-bis[(4-hydroxy-3,5-dimethoxyphenyl)methylene]-
CAS 56720-22-0C23H24O7
Cyclopentanone, 2,5-bis[(3,4,5-trihydroxyphenyl)methylene]-, (2E,5E)- chemical structure, C19H16O7, CAS 672327-35-4
Cyclopentanone, 2,5-bis[(3,4,5-trihydroxyphenyl)methylene]-, (2E,5E)-
CAS 672327-35-4C19H16O7
2,5-Bis[(4-hydroxyphenyl)methylidene]cyclopentan-1-one chemical structure, C19H16O3, CAS 1351486-66-2
2,5-Bis[(4-hydroxyphenyl)methylidene]cyclopentan-1-one
CAS 1351486-66-2C19H16O3
2,5-Bis(4-chlorobenzylidene)cyclopentanone chemical structure, C19H14Cl2O, CAS 42019-88-5
2,5-Bis(4-chlorobenzylidene)cyclopentanone
CAS 42019-88-5C19H14Cl2O
(2E,5E)-2,5-Bis[(4-fluorophenyl)methylidene]cyclopentan-1-one chemical structure, C19H14F2O, CAS 398-84-5
(2E,5E)-2,5-Bis[(4-fluorophenyl)methylidene]cyclopentan-1-one
CAS 398-84-5C19H14F2O
(2E,5E)-2,5-Bis[(4-methoxyphenyl)methylidene]cyclopentan-1-one chemical structure, C21H20O3, CAS 5447-53-0
(2E,5E)-2,5-Bis[(4-methoxyphenyl)methylidene]cyclopentan-1-one
CAS 5447-53-0C21H20O3
2,5-Bis[(4-hydroxy-3,5-dimethoxyphenyl)methylidene]cyclopentan-1-one chemical structure, C23H24O7
2,5-Bis[(4-hydroxy-3,5-dimethoxyphenyl)methylidene]cyclopentan-1-one
C23H24O7
2,5-Bis[(3,4,5-trimethoxyphenyl)methylidene]cyclopentan-1-one chemical structure, C25H28O7, CAS 325745-36-6
2,5-Bis[(3,4,5-trimethoxyphenyl)methylidene]cyclopentan-1-one
CAS 325745-36-6C25H28O7
Cyclopentanone, 2,5-bis[(3,4-dimethoxyphenyl)methylene]-, (E,E)- chemical structure, C23H24O5, CAS 106115-49-5
Cyclopentanone, 2,5-bis[(3,4-dimethoxyphenyl)methylene]-, (E,E)-
CAS 106115-49-5C23H24O5
Cyclopentanone, 2,5-bis[(2-chlorophenyl)methylene]- chemical structure, C19H14Cl2O, CAS 92918-49-5
Cyclopentanone, 2,5-bis[(2-chlorophenyl)methylene]-
CAS 92918-49-5C19H14Cl2O
Cyclopentanone, 2,5-bis[(2-hydroxyphenyl)methylene]- chemical structure, C19H16O3, CAS 61390-20-3
Cyclopentanone, 2,5-bis[(2-hydroxyphenyl)methylene]-
CAS 61390-20-3C19H16O3
2,5-Bis(3-chloro-4,5-dimethoxybenzylidene)cyclopentan-1-one chemical structure, C23H22Cl2O5, CAS 494843-62-8
2,5-Bis(3-chloro-4,5-dimethoxybenzylidene)cyclopentan-1-one
CAS 494843-62-8C23H22Cl2O5
Cyclopentanone, 2,5-bis[(3,5-dibromo-2-hydroxyphenyl)methylene]- chemical structure, C19H12Br4O3, CAS 61732-62-5
Cyclopentanone, 2,5-bis[(3,5-dibromo-2-hydroxyphenyl)methylene]-
CAS 61732-62-5C19H12Br4O3
Cyclopentanone, 2,5-bis[(3-nitrophenyl)methylene]- chemical structure, C19H14N2O5, CAS 273724-34-8
Cyclopentanone, 2,5-bis[(3-nitrophenyl)methylene]-
CAS 273724-34-8C19H14N2O5
Cyclopentanone, 2,5-bis[(2-methoxyphenyl)methylene]- chemical structure, C21H20O3, CAS 577995-40-5
Cyclopentanone, 2,5-bis[(2-methoxyphenyl)methylene]-
CAS 577995-40-5C21H20O3
Cyclopentanone, 2,5-bis[(3-bromophenyl)methylene]- chemical structure, C19H14Br2O, CAS 138197-90-7
Cyclopentanone, 2,5-bis[(3-bromophenyl)methylene]-
CAS 138197-90-7C19H14Br2O
Cyclopentanone, 2-[(4-methoxyphenyl)methylene]-5-(phenylmethylene)- chemical structure, C20H18O2, CAS 62643-70-3
Cyclopentanone, 2-[(4-methoxyphenyl)methylene]-5-(phenylmethylene)-
CAS 62643-70-3C20H18O2
2,5-Bis(2-bromo-4-isopropoxy-5-methoxybenzylidene)cyclopentan-1-one chemical structure, C27H30Br2O5, CAS 445254-68-2
2,5-Bis(2-bromo-4-isopropoxy-5-methoxybenzylidene)cyclopentan-1-one
CAS 445254-68-2C27H30Br2O5
4,4'-[(2-Oxocyclopentane-1,3-diylidene)dimethanylylidene]dibenzonitrile chemical structure, C21H14N2O, CAS 63476-65-3
4,4'-[(2-Oxocyclopentane-1,3-diylidene)dimethanylylidene]dibenzonitrile
CAS 63476-65-3C21H14N2O
2,5-Bis-(4-methyl-benzylidene)-cyclopentanone chemical structure, C21H20O, CAS 106115-47-3
2,5-Bis-(4-methyl-benzylidene)-cyclopentanone
CAS 106115-47-3C21H20O
2,5-Dibenzylidenecyclopentanone chemical structure, C19H16O, CAS 895-80-7
2,5-Dibenzylidenecyclopentanone
CAS 895-80-7C19H16O
2-(4-Chlorobenzylidene)-5-(4-methoxybenzylidene)cyclopentanone chemical structure, C20H17ClO2, CAS 62643-69-0
2-(4-Chlorobenzylidene)-5-(4-methoxybenzylidene)cyclopentanone
CAS 62643-69-0C20H17ClO2
(2E,5E)-2,5-Bis[(2-fluorophenyl)methylidene]cyclopentan-1-one chemical structure, C19H14F2O, CAS 1158188-88-5
(2E,5E)-2,5-Bis[(2-fluorophenyl)methylidene]cyclopentan-1-one
CAS 1158188-88-5C19H14F2O