CompoundList
Sign in
Murcko scaffold

2-(Pyrrolidin-2-yl)-1H-imidazole scaffold

89 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
89
With full pages
8
Scaffold SMILES

c1c[nH]c(C2CCCN2)n1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(Pyrrolidin-2-yl)-1H-imidazole page
Murcko scaffold c1c[nH]c(C2CCCN2)n1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 89 chemicals

2-(Pyrrolidin-2-yl)-1H-imidazole chemical structure, C7H11N3, CAS 871716-71-1
2-(Pyrrolidin-2-yl)-1H-imidazole
CAS 871716-71-1C7H11N3
2-(Pyrrolidin-2-yl)-5-(trifluoromethyl)-1H-imidazole chemical structure, C8H10F3N3, CAS 1153101-35-9
2-(Pyrrolidin-2-yl)-5-(trifluoromethyl)-1H-imidazole
CAS 1153101-35-9C8H10F3N3
4,5-Dimethyl-2-(pyrrolidin-2-yl)-1H-imidazole chemical structure, C9H15N3, CAS 1153102-08-9
4,5-Dimethyl-2-(pyrrolidin-2-yl)-1H-imidazole
CAS 1153102-08-9C9H15N3
4-(tert-Butyl)-2-(pyrrolidin-2-yl)-1H-imidazole chemical structure, C11H19N3, CAS 1153104-89-2
4-(tert-Butyl)-2-(pyrrolidin-2-yl)-1H-imidazole
CAS 1153104-89-2C11H19N3
(s)-5-Bromo-2-(pyrrolidin-2-yl)-1H-imidazole hydrochloride chemical structure, C7H11BrClN3, CAS 1258234-18-2
(s)-5-Bromo-2-(pyrrolidin-2-yl)-1H-imidazole hydrochloride
CAS 1258234-18-2C7H11BrClN3
5-Bromo-2-[(2S)-pyrrolidin-2-yl]-1H-imidazole chemical structure, C7H10BrN3, CAS 1258253-82-5
5-Bromo-2-[(2S)-pyrrolidin-2-yl]-1H-imidazole
CAS 1258253-82-5C7H10BrN3
tert-Butyl (2S)-2-(1H-imidazol-2-yl)pyrrolidine-1-carboxylate chemical structure, C12H19N3O2, CAS 1007882-58-7
tert-Butyl (2S)-2-(1H-imidazol-2-yl)pyrrolidine-1-carboxylate
CAS 1007882-58-7C12H19N3O2
(S)-2-(Pyrrolidin-2-yl)-1H-imidazole hydrochloride chemical structure, C7H12ClN3, CAS 2656419-04-2
(S)-2-(Pyrrolidin-2-yl)-1H-imidazole hydrochloride
CAS 2656419-04-2C7H12ClN3
tert-Butyl 2-(4,5-dibromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate chemical structure, C12H17Br2N3O2, CAS 1823447-39-7
tert-Butyl 2-(4,5-dibromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate
CAS 1823447-39-7C12H17Br2N3O2
(S)-tert-Butyl 2-(4,5-dibromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate chemical structure, C12H17Br2N3O2, CAS 1240893-76-8
(S)-tert-Butyl 2-(4,5-dibromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate
CAS 1240893-76-8C12H17Br2N3O2
1,1-Dimethylethyl (2S)-2-(5-bromo-1H-imidazol-2-yl)-1-pyrrolidinecarboxylate chemical structure, C12H18BrN3O2, CAS 1007882-59-8
1,1-Dimethylethyl (2S)-2-(5-bromo-1H-imidazol-2-yl)-1-pyrrolidinecarboxylate
CAS 1007882-59-8C12H18BrN3O2
tert-Butyl 2-(5-bromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate chemical structure, C12H18BrN3O2, CAS 1352718-88-7
tert-Butyl 2-(5-bromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate
CAS 1352718-88-7C12H18BrN3O2
tert-Butyl 4-bromo-2-[(2S)-1-(tert-butoxycarbonyl)pyrrolidin-2-yl]-1H-imidazole-1-carboxylate chemical structure, C17H26BrN3O4, CAS 1242094-13-8
tert-Butyl 4-bromo-2-[(2S)-1-(tert-butoxycarbonyl)pyrrolidin-2-yl]-1H-imidazole-1-carboxylate
CAS 1242094-13-8C17H26BrN3O4
Methyl ((S)-1-((S)-2-(5-bromo-1H-imidazol-2-yl)pyrrolidin-1-yl)-3-methyl-1-oxobutan-2-yl)carbamate chemical structure, C14H21BrN4O3, CAS 1292836-05-5
Methyl ((S)-1-((S)-2-(5-bromo-1H-imidazol-2-yl)pyrrolidin-1-yl)-3-methyl-1-oxobutan-2-yl)carbamate
CAS 1292836-05-5C14H21BrN4O3
(S)-tert-Butyl 2-(5-iodo-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazol-2-yl)pyrrolidine-1-carboxylate chemical structure, C18H32IN3O3Si, CAS 1228669-46-2
(S)-tert-Butyl 2-(5-iodo-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazol-2-yl)pyrrolidine-1-carboxylate
CAS 1228669-46-2C18H32IN3O3Si
5-Bromo-2-((S)-1-tert-butoxycarbonyl-pyrrolidin-2-yl)-imidazole-1-carboxylic acid tert-butyl ester chemical structure, C17H26BrN3O4, CAS 1240894-15-8
5-Bromo-2-((S)-1-tert-butoxycarbonyl-pyrrolidin-2-yl)-imidazole-1-carboxylic acid tert-butyl ester
CAS 1240894-15-8C17H26BrN3O4
(S)-tert-Butyl 2-(1-((2-(trimethylsilyl)ethoxy)methyl)-4-bromo-5-fluoro-1H-imidazol-2-yl)pyrrolidine-1-carboxylate chemical structure, C18H31BrFN3O3Si, CAS 1334313-17-5
(S)-tert-Butyl 2-(1-((2-(trimethylsilyl)ethoxy)methyl)-4-bromo-5-fluoro-1H-imidazol-2-yl)pyrrolidine-1-carboxylate
CAS 1334313-17-5C18H31BrFN3O3Si
(S)-tert-Butyl 2-(1-((2-(trimethylsilyl)ethoxy)methyl)-4,5-dibromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate chemical structure, C18H31Br2N3O3Si, CAS 1352843-11-8
(S)-tert-Butyl 2-(1-((2-(trimethylsilyl)ethoxy)methyl)-4,5-dibromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate
CAS 1352843-11-8C18H31Br2N3O3Si
(S)-tert-Butyl 2-(5-((trimethylsilyl)ethynyl)-1H-imidazol-2-yl)pyrrolidine-1-carboxylate chemical structure, C17H27N3O2Si, CAS 1228968-97-5
(S)-tert-Butyl 2-(5-((trimethylsilyl)ethynyl)-1H-imidazol-2-yl)pyrrolidine-1-carboxylate
CAS 1228968-97-5C17H27N3O2Si
(S)-tert-Butyl 2-(5-iodo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate chemical structure, C12H18IN3O2, CAS 1228552-62-2
(S)-tert-Butyl 2-(5-iodo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate
CAS 1228552-62-2C12H18IN3O2
(S)-tert-Butyl 2-(5-ethynyl-1H-imidazol-2-yl)pyrrolidine-1-carboxylate chemical structure, C14H19N3O2, CAS 1228968-98-6
(S)-tert-Butyl 2-(5-ethynyl-1H-imidazol-2-yl)pyrrolidine-1-carboxylate
CAS 1228968-98-6C14H19N3O2
tert-Butyl 2-(5-iodo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate chemical structure, C12H18IN3O2, CAS 1560648-60-3
tert-Butyl 2-(5-iodo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate
CAS 1560648-60-3C12H18IN3O2
(S)-tert-Butyl 2-(4,5-diiodo-1H-imidazol-2-yl)-pyrrolidine-1-carboxylate chemical structure, C12H17I2N3O2, CAS 1228968-38-4
(S)-tert-Butyl 2-(4,5-diiodo-1H-imidazol-2-yl)-pyrrolidine-1-carboxylate
CAS 1228968-38-4C12H17I2N3O2
tert-Butyl 2-(1H-imidazol-2-yl)pyrrolidine-1-carboxylate chemical structure, C12H19N3O2, CAS 1352719-15-3
tert-Butyl 2-(1H-imidazol-2-yl)pyrrolidine-1-carboxylate
CAS 1352719-15-3C12H19N3O2