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Murcko scaffold

Ring system with 3 rings and 22 atoms

12 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
12
With full pages
3
Scaffold SMILES

O=S(=O)(C=Cc1ccc(-c2ccccc2)o1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(C=Cc1ccc(-c2ccccc2)o1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

3-(5-(2-Nitrophenyl)-2-furyl)-2-(phenylsulfonyl)acrylonitrile chemical structure, C19H12N2O5S, CAS 374546-78-8
3-(5-(2-Nitrophenyl)-2-furyl)-2-(phenylsulfonyl)acrylonitrile
CAS 374546-78-8C19H12N2O5S
2-((4-Methylphenyl)sulfonyl)-3-(5-(3-nitrophenyl)-2-furyl)acrylonitrile chemical structure, C20H14N2O5S, CAS 374544-29-3
2-((4-Methylphenyl)sulfonyl)-3-(5-(3-nitrophenyl)-2-furyl)acrylonitrile
CAS 374544-29-3C20H14N2O5S
3-(5-(4-Chlorophenyl)-2-furyl)-2-((4-methylphenyl)sulfonyl)acrylonitrile chemical structure, C20H14ClNO3S, CAS 374611-66-2
3-(5-(4-Chlorophenyl)-2-furyl)-2-((4-methylphenyl)sulfonyl)acrylonitrile
CAS 374611-66-2C20H14ClNO3S
(2E)-2-(Benzenesulfonyl)-3-[5-(4-chlorophenyl)-furan-2-yl]prop-2-enenitrile chemical structure, C19H12ClNO3S, CAS 64251-72-5
(2E)-2-(Benzenesulfonyl)-3-[5-(4-chlorophenyl)-furan-2-yl]prop-2-enenitrile
CAS 64251-72-5C19H12ClNO3S
2-(Benzenesulfonyl)-3-[5-(4-bromophenyl)furan-2-yl]prop-2-enenitrile chemical structure, C19H12BrNO3S, CAS 64251-73-6
2-(Benzenesulfonyl)-3-[5-(4-bromophenyl)furan-2-yl]prop-2-enenitrile
CAS 64251-73-6C19H12BrNO3S
2-(Benzenesulfonyl)-3-[5-(2,5-dichlorophenyl)furan-2-yl]prop-2-enenitrile chemical structure, C19H11Cl2NO3S, CAS 374087-60-2
2-(Benzenesulfonyl)-3-[5-(2,5-dichlorophenyl)furan-2-yl]prop-2-enenitrile
CAS 374087-60-2C19H11Cl2NO3S
2-(Benzenesulfonyl)-3-[5-(2-chlorophenyl)furan-2-yl]prop-2-enenitrile chemical structure, C19H12ClNO3S, CAS 373614-13-2
2-(Benzenesulfonyl)-3-[5-(2-chlorophenyl)furan-2-yl]prop-2-enenitrile
CAS 373614-13-2C19H12ClNO3S
(2E)-3-[5-(4-Acetylphenyl)furan-2-yl]-2-(phenylsulfonyl)prop-2-enenitrile chemical structure, C21H15NO4S, CAS 865593-37-9
(2E)-3-[5-(4-Acetylphenyl)furan-2-yl]-2-(phenylsulfonyl)prop-2-enenitrile
CAS 865593-37-9C21H15NO4S
(E)-2-((4-Chlorophenyl)sulfonyl)-3-(5-(4-fluorophenyl)furan-2-yl)acrylonitrile chemical structure, C19H11ClFNO3S, CAS 865593-39-1
(E)-2-((4-Chlorophenyl)sulfonyl)-3-(5-(4-fluorophenyl)furan-2-yl)acrylonitrile
CAS 865593-39-1C19H11ClFNO3S
(E)-4-(5-(2-((4-Bromophenyl)sulfonyl)-2-cyanovinyl)furan-2-yl)benzenesulfonamide chemical structure, C19H13BrN2O5S2, CAS 622356-44-9
(E)-4-(5-(2-((4-Bromophenyl)sulfonyl)-2-cyanovinyl)furan-2-yl)benzenesulfonamide
CAS 622356-44-9C19H13BrN2O5S2
(E)-4-(5-(2-((4-Chlorophenyl)sulfonyl)-2-cyanovinyl)furan-2-yl)benzenesulfonamide chemical structure, C19H13ClN2O5S2, CAS 620576-04-7
(E)-4-(5-(2-((4-Chlorophenyl)sulfonyl)-2-cyanovinyl)furan-2-yl)benzenesulfonamide
CAS 620576-04-7C19H13ClN2O5S2
2-(Benzenesulfonyl)-3-[5-(4-methylphenyl)furan-2-yl]prop-2-enenitrile chemical structure, C20H15NO3S, CAS 64251-69-0
2-(Benzenesulfonyl)-3-[5-(4-methylphenyl)furan-2-yl]prop-2-enenitrile
CAS 64251-69-0C20H15NO3S