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Murcko scaffold

N-(2-Phenylethyl)-1,3-benzodioxole-5-carboxamide scaffold

16 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
16
With full pages
3
Scaffold SMILES

O=C(NCCc1ccccc1)c1ccc2c(c1)OCO2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-(2-Phenylethyl)-1,3-benzodioxole-5-carboxamide page
Murcko scaffold O=C(NCCc1ccccc1)c1ccc2c(c1)OCO2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

N-[2-(4-Methoxyphenyl)ethyl]-6-nitro-1,3-benzodioxole-5-carboxamide chemical structure, C17H16N2O6, CAS 34103-60-1
N-[2-(4-Methoxyphenyl)ethyl]-6-nitro-1,3-benzodioxole-5-carboxamide
CAS 34103-60-1C17H16N2O6
N-[2-(2-Hydroxyphenyl)ethyl]-6-nitro-1,3-benzodioxole-5-carboxamide chemical structure, C16H14N2O6, CAS 20286-81-1
N-[2-(2-Hydroxyphenyl)ethyl]-6-nitro-1,3-benzodioxole-5-carboxamide
CAS 20286-81-1C16H14N2O6
N-(2-Phenylethyl)-1,3-benzodioxole-5-carboxamide chemical structure, C16H15NO3, CAS 349114-09-6
N-(2-Phenylethyl)-1,3-benzodioxole-5-carboxamide
CAS 349114-09-6C16H15NO3
N-[2-(4-Sulfamoylphenyl)ethyl]-1,3-benzodioxole-5-carboxamide chemical structure, C16H16N2O5S, CAS 25197-17-5
N-[2-(4-Sulfamoylphenyl)ethyl]-1,3-benzodioxole-5-carboxamide
CAS 25197-17-5C16H16N2O5S
N-[2-(3,4-Dimethoxyphenyl)ethyl]-1,3-benzodioxole-5-carboxamide chemical structure, C18H19NO5, CAS 18780-56-8
N-[2-(3,4-Dimethoxyphenyl)ethyl]-1,3-benzodioxole-5-carboxamide
CAS 18780-56-8C18H19NO5
N-(4-(Dimethylamino)phenethyl)benzo[d][1,3]dioxole-5-carboxamide chemical structure, C18H20N2O3, CAS 953244-32-1
N-(4-(Dimethylamino)phenethyl)benzo[d][1,3]dioxole-5-carboxamide
CAS 953244-32-1C18H20N2O3
6-Nitro-N-(2-phenylethyl)-1,3-benzodioxole-5-carboxamide chemical structure, C16H14N2O5, CAS 380905-72-6
6-Nitro-N-(2-phenylethyl)-1,3-benzodioxole-5-carboxamide
CAS 380905-72-6C16H14N2O5
N-(3,3,3-Trifluoro-2-hydroxy-2-phenylpropyl)benzo[d][1,3]dioxole-5-carboxamide chemical structure, C17H14F3NO4, CAS 1351661-86-3
N-(3,3,3-Trifluoro-2-hydroxy-2-phenylpropyl)benzo[d][1,3]dioxole-5-carboxamide
CAS 1351661-86-3C17H14F3NO4
N-(2-(4-(Dimethylamino)phenyl)-2-hydroxyethyl)benzo[d][1,3]dioxole-5-carboxamide chemical structure, C18H20N2O4, CAS 1421444-52-1
N-(2-(4-(Dimethylamino)phenyl)-2-hydroxyethyl)benzo[d][1,3]dioxole-5-carboxamide
CAS 1421444-52-1C18H20N2O4
N-(2-Hydroxy-2-(4-(methylthio)phenyl)ethyl)benzo[d][1,3]dioxole-5-carboxamide chemical structure, C17H17NO4S, CAS 1448065-60-8
N-(2-Hydroxy-2-(4-(methylthio)phenyl)ethyl)benzo[d][1,3]dioxole-5-carboxamide
CAS 1448065-60-8C17H17NO4S
N-(2-Methoxy-2-(o-tolyl)ethyl)benzo[d][1,3]dioxole-5-carboxamide chemical structure, C18H19NO4, CAS 1797892-47-7
N-(2-Methoxy-2-(o-tolyl)ethyl)benzo[d][1,3]dioxole-5-carboxamide
CAS 1797892-47-7C18H19NO4
N-[2-(2-Fluorophenyl)-2-methoxypropyl]-2H-1,3-benzodioxole-5-carboxamide chemical structure, C18H18FNO4, CAS 1797558-57-6
N-[2-(2-Fluorophenyl)-2-methoxypropyl]-2H-1,3-benzodioxole-5-carboxamide
CAS 1797558-57-6C18H18FNO4
N-(2-(3,4-Dimethoxyphenyl)-2-hydroxyethyl)benzo[d][1,3]dioxole-5-carboxamide chemical structure, C18H19NO6, CAS 1797063-38-7
N-(2-(3,4-Dimethoxyphenyl)-2-hydroxyethyl)benzo[d][1,3]dioxole-5-carboxamide
CAS 1797063-38-7C18H19NO6
N-(2-(3-Fluorophenyl)-2-methoxyethyl)benzo[d][1,3]dioxole-5-carboxamide chemical structure, C17H16FNO4, CAS 1798037-89-4
N-(2-(3-Fluorophenyl)-2-methoxyethyl)benzo[d][1,3]dioxole-5-carboxamide
CAS 1798037-89-4C17H16FNO4
N-(2-Methoxy-2-(2-methoxyphenyl)ethyl)benzo[d][1,3]dioxole-5-carboxamide chemical structure, C18H19NO5, CAS 1790197-97-5
N-(2-Methoxy-2-(2-methoxyphenyl)ethyl)benzo[d][1,3]dioxole-5-carboxamide
CAS 1790197-97-5C18H19NO5
N-(2-(2-Chlorophenyl)-2-methoxyethyl)benzo[d][1,3]dioxole-5-carboxamide chemical structure, C17H16ClNO4, CAS 1798515-66-8
N-(2-(2-Chlorophenyl)-2-methoxyethyl)benzo[d][1,3]dioxole-5-carboxamide
CAS 1798515-66-8C17H16ClNO4