CompoundList
Sign in
Murcko scaffold

Ring system with 2 rings and 17 atoms

14 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
17
Chemicals
14
With full pages
3
Scaffold SMILES

O=C(CN1C(=O)CCC1=O)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CN1C(=O)CCC1=O)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

Ethyl 4-[2-(2,5-dioxopyrrolidin-1-yl)acetamido]benzoate chemical structure, C15H16N2O5, CAS 328003-82-3
Ethyl 4-[2-(2,5-dioxopyrrolidin-1-yl)acetamido]benzoate
CAS 328003-82-3C15H16N2O5
N-(4-Bromophenyl)-2-(2,5-dioxopyrrolidin-1-yl)acetamide chemical structure, C12H11BrN2O3, CAS 476308-87-9
N-(4-Bromophenyl)-2-(2,5-dioxopyrrolidin-1-yl)acetamide
CAS 476308-87-9C12H11BrN2O3
N-(4-Bromo-3-chlorophenyl)-2-(2,5-dioxopyrrolidin-1-yl)acetamide chemical structure, C12H10BrClN2O3, CAS 838887-32-4
N-(4-Bromo-3-chlorophenyl)-2-(2,5-dioxopyrrolidin-1-yl)acetamide
CAS 838887-32-4C12H10BrClN2O3
N-(4-Acetylphenyl)-2-(2,5-dioxopyrrolidin-1-yl)acetamide chemical structure, C14H14N2O4, CAS 163487-73-8
N-(4-Acetylphenyl)-2-(2,5-dioxopyrrolidin-1-yl)acetamide
CAS 163487-73-8C14H14N2O4
2-(2,5-Dioxopyrrolidin-1-yl)-N-(2-methoxy-4-nitrophenyl)acetamide chemical structure, C13H13N3O6, CAS 329905-30-8
2-(2,5-Dioxopyrrolidin-1-yl)-N-(2-methoxy-4-nitrophenyl)acetamide
CAS 329905-30-8C13H13N3O6
2-(2,5-Dioxopyrrolidin-1-yl)-N-(4-sulfamoylphenyl)propanamide chemical structure, C13H15N3O5S, CAS 296771-09-0
2-(2,5-Dioxopyrrolidin-1-yl)-N-(4-sulfamoylphenyl)propanamide
CAS 296771-09-0C13H15N3O5S
N-(3-Acetylphenyl)-2-(2,5-dioxopyrrolidin-1-yl)acetamide chemical structure, C14H14N2O4, CAS 476308-73-3
N-(3-Acetylphenyl)-2-(2,5-dioxopyrrolidin-1-yl)acetamide
CAS 476308-73-3C14H14N2O4
2-(2,5-Dioxopyrrolidin-1-yl)-N-(4-methoxy-2-nitrophenyl)acetamide chemical structure, C13H13N3O6, CAS 329903-05-1
2-(2,5-Dioxopyrrolidin-1-yl)-N-(4-methoxy-2-nitrophenyl)acetamide
CAS 329903-05-1C13H13N3O6
2-(2,5-Dioxopyrrolidin-1-yl)-N-mesitylacetamide chemical structure, C15H18N2O3, CAS 899362-10-8
2-(2,5-Dioxopyrrolidin-1-yl)-N-mesitylacetamide
CAS 899362-10-8C15H18N2O3
N-(3,4-Dimethylphenyl)-2-(2,5-dioxopyrrolidin-1-yl)acetamide chemical structure, C14H16N2O3, CAS 923113-53-5
N-(3,4-Dimethylphenyl)-2-(2,5-dioxopyrrolidin-1-yl)acetamide
CAS 923113-53-5C14H16N2O3
N-(2-Cyanophenyl)-2-(2,5-dioxopyrrolidin-1-yl)acetamide chemical structure, C13H11N3O3, CAS 1019572-93-0
N-(2-Cyanophenyl)-2-(2,5-dioxopyrrolidin-1-yl)acetamide
CAS 1019572-93-0C13H11N3O3
4-Chloro-3-[[2-(2,5-dioxo-1-pyrrolidinyl)acetyl]amino]benzoic acid chemical structure, C13H11ClN2O5, CAS 1152833-64-1
4-Chloro-3-[[2-(2,5-dioxo-1-pyrrolidinyl)acetyl]amino]benzoic acid
CAS 1152833-64-1C13H11ClN2O5
2-(2,5-Dioxopyrrolidin-1-yl)-N-(4-(2-oxo-2-((2,2,2-trifluoroethyl)amino)ethyl)phenyl)acetamide chemical structure, C16H16F3N3O4, CAS 1235073-73-0
2-(2,5-Dioxopyrrolidin-1-yl)-N-(4-(2-oxo-2-((2,2,2-trifluoroethyl)amino)ethyl)phenyl)acetamide
CAS 1235073-73-0C16H16F3N3O4
N-(4-Chloro-3-fluorophenyl)-2-(2,5-dioxopyrrolidin-1-yl)acetamide chemical structure, C12H10ClFN2O3, CAS 2327272-89-7
N-(4-Chloro-3-fluorophenyl)-2-(2,5-dioxopyrrolidin-1-yl)acetamide
CAS 2327272-89-7C12H10ClFN2O3