CompoundList
Sign in
Murcko scaffold

Ring system with 2 rings and 13 atoms

39 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
39
With full pages
3
Scaffold SMILES

c1ccc(Nc2ccncn2)nc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Nc2ccncn2)nc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 39 of 39 chemicals

3-Pyridinethiol, 2-((2,4-diamino-6-pyrimidinyl)amino)-6-methyl- chemical structure, C10H12N6S, CAS 81587-37-3
3-Pyridinethiol, 2-((2,4-diamino-6-pyrimidinyl)amino)-6-methyl-
CAS 81587-37-3C10H12N6S
N4-(6-methylpyridin-2-yl)-5-nitropyrimidine-4,6-diamine chemical structure, C10H10N6O2, CAS 450345-58-1
N4-(6-methylpyridin-2-yl)-5-nitropyrimidine-4,6-diamine
CAS 450345-58-1C10H10N6O2
5-Nitro-N-2-pyridinyl-4,6-pyrimidinediamine chemical structure, C9H8N6O2, CAS 497063-63-5
5-Nitro-N-2-pyridinyl-4,6-pyrimidinediamine
CAS 497063-63-5C9H8N6O2
3-Pyridinethiol, 2-((2,4-dimethoxy-6-pyrimidinyl)amino)-6-methyl- chemical structure, C12H14N4O2S, CAS 55740-62-0
3-Pyridinethiol, 2-((2,4-dimethoxy-6-pyrimidinyl)amino)-6-methyl-
CAS 55740-62-0C12H14N4O2S
3-Pyridinethiol, 2-((2-amino-4-methyl-6-pyrimidinyl)amino)-6-methyl- chemical structure, C11H13N5S, CAS 81587-36-2
3-Pyridinethiol, 2-((2-amino-4-methyl-6-pyrimidinyl)amino)-6-methyl-
CAS 81587-36-2C11H13N5S
3-Pyridinethiol, 2-((2,4-dichloro-6-pyrimidinyl)amino)-6-methyl- chemical structure, C10H8Cl2N4S, CAS 81587-38-4
3-Pyridinethiol, 2-((2,4-dichloro-6-pyrimidinyl)amino)-6-methyl-
CAS 81587-38-4C10H8Cl2N4S
3-Pyridinethiol, 2-((4-amino-2-(methylthio)-6-pyrimidinyl)amino)-6-methyl- chemical structure, C11H13N5S2, CAS 81587-39-5
3-Pyridinethiol, 2-((4-amino-2-(methylthio)-6-pyrimidinyl)amino)-6-methyl-
CAS 81587-39-5C11H13N5S2
3-Pyridinethiol, 2-((2-amino-4-chloro-6-pyrimidinyl)amino)-6-methyl- chemical structure, C10H10ClN5S, CAS 81587-40-8
3-Pyridinethiol, 2-((2-amino-4-chloro-6-pyrimidinyl)amino)-6-methyl-
CAS 81587-40-8C10H10ClN5S
4-N-(3-Methylpyridin-2-yl)-5-nitropyrimidine-4,6-diamine chemical structure, C10H10N6O2, CAS 497063-62-4
4-N-(3-Methylpyridin-2-yl)-5-nitropyrimidine-4,6-diamine
CAS 497063-62-4C10H10N6O2
(5-Bromo-2-chloro-pyrimidin-4-yl)-pyridin-2-yl-amine chemical structure, C9H6BrClN4, CAS 280582-65-2
(5-Bromo-2-chloro-pyrimidin-4-yl)-pyridin-2-yl-amine
CAS 280582-65-2C9H6BrClN4
6-Chloro-N-(pyridin-2-yl)pyrimidin-4-amine chemical structure, C9H7ClN4, CAS 26422-83-3
6-Chloro-N-(pyridin-2-yl)pyrimidin-4-amine
CAS 26422-83-3C9H7ClN4
2-Chloro-N-2-pyridinyl-4-pyrimidinamine chemical structure, C9H7ClN4, CAS 868366-57-8
2-Chloro-N-2-pyridinyl-4-pyrimidinamine
CAS 868366-57-8C9H7ClN4
N4-(5-Bromo-2-pyridinyl)-N6-(3-methoxypropyl)-5-nitro-4,6-pyrimidinediamine chemical structure, C13H15BrN6O3, CAS 884982-98-3
N4-(5-Bromo-2-pyridinyl)-N6-(3-methoxypropyl)-5-nitro-4,6-pyrimidinediamine
CAS 884982-98-3C13H15BrN6O3
6-(2-Pyridinylamino)-4-pyrimidinecarboxylic acid chemical structure, C10H8N4O2, CAS 1097256-05-7
6-(2-Pyridinylamino)-4-pyrimidinecarboxylic acid
CAS 1097256-05-7C10H8N4O2
5-Chloro-6-(pyridin-2-ylamino)pyrimidine-4-carboxylic acid chemical structure, C10H7ClN4O2, CAS 1097254-02-8
5-Chloro-6-(pyridin-2-ylamino)pyrimidine-4-carboxylic acid
CAS 1097254-02-8C10H7ClN4O2
2-Chloro-N-(4-(trifluoromethyl)pyridin-2-yl)pyrimidin-4-amine chemical structure, C10H6ClF3N4, CAS 1361197-71-8
2-Chloro-N-(4-(trifluoromethyl)pyridin-2-yl)pyrimidin-4-amine
CAS 1361197-71-8C10H6ClF3N4
N-[2-({6-[(Pyridin-2-yl)amino]pyrimidin-4-yl}amino)ethyl]propanamide chemical structure, C14H18N6O, CAS 1421483-18-2
N-[2-({6-[(Pyridin-2-yl)amino]pyrimidin-4-yl}amino)ethyl]propanamide
CAS 1421483-18-2C14H18N6O
N-(2-((2-Methyl-6-(pyridin-2-ylamino)pyrimidin-4-yl)amino)ethyl)acetamide chemical structure, C14H18N6O, CAS 1428349-07-8
N-(2-((2-Methyl-6-(pyridin-2-ylamino)pyrimidin-4-yl)amino)ethyl)acetamide
CAS 1428349-07-8C14H18N6O
N-(2-((2-Methyl-6-((4-methylpyridin-2-yl)amino)pyrimidin-4-yl)amino)ethyl)pivalamide chemical structure, C18H26N6O, CAS 1428356-42-6
N-(2-((2-Methyl-6-((4-methylpyridin-2-yl)amino)pyrimidin-4-yl)amino)ethyl)pivalamide
CAS 1428356-42-6C18H26N6O
2-Methoxy-N-[2-({2-methyl-6-[(4-methylpyridin-2-yl)amino]pyrimidin-4-YL}amino)ethyl]acetamide chemical structure, C16H22N6O2, CAS 1428370-64-2
2-Methoxy-N-[2-({2-methyl-6-[(4-methylpyridin-2-yl)amino]pyrimidin-4-YL}amino)ethyl]acetamide
CAS 1428370-64-2C16H22N6O2
N-(2-((2-Methyl-6-(pyridin-2-ylamino)pyrimidin-4-yl)amino)ethyl)ethanesulfonamide chemical structure, C14H20N6O2S, CAS 1428356-09-5
N-(2-((2-Methyl-6-(pyridin-2-ylamino)pyrimidin-4-yl)amino)ethyl)ethanesulfonamide
CAS 1428356-09-5C14H20N6O2S
N-[2-({2-Methyl-6-[(4-methylpyridin-2-yl)amino]pyrimidin-4-YL}amino)ethyl]methanesulfonamide chemical structure, C14H20N6O2S, CAS 1428371-54-3
N-[2-({2-Methyl-6-[(4-methylpyridin-2-yl)amino]pyrimidin-4-YL}amino)ethyl]methanesulfonamide
CAS 1428371-54-3C14H20N6O2S
2-Methyl-N-(pyridin-2-yl)pyrimidin-4-amine chemical structure, C10H10N4, CAS 2319800-66-1
2-Methyl-N-(pyridin-2-yl)pyrimidin-4-amine
CAS 2319800-66-1C10H10N4
N4-(2-Aminoethyl)-2-methyl-N6-(pyridin-2-yl)pyrimidine-4,6-diamine chemical structure, C12H16N6, CAS 1904122-12-8
N4-(2-Aminoethyl)-2-methyl-N6-(pyridin-2-yl)pyrimidine-4,6-diamine
CAS 1904122-12-8C12H16N6