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Murcko scaffold

N,5-Diphenyl-1,2-oxazole-3-carboxamide scaffold

55 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
55
With full pages
15
Scaffold SMILES

O=C(Nc1ccccc1)c1cc(-c2ccccc2)on1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N,5-Diphenyl-1,2-oxazole-3-carboxamide page
Murcko scaffold O=C(Nc1ccccc1)c1cc(-c2ccccc2)on1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 55 chemicals

N-(4-Chlorophenyl)-5-phenyl-1,2-oxazole-3-carboxamide chemical structure, C16H11ClN2O2, CAS 107402-55-1
N-(4-Chlorophenyl)-5-phenyl-1,2-oxazole-3-carboxamide
CAS 107402-55-1C16H11ClN2O2
N-(2-Ethylphenyl)-5-phenyl-3-isoxazolecarboxamide chemical structure, C18H16N2O2, CAS 712347-86-9
N-(2-Ethylphenyl)-5-phenyl-3-isoxazolecarboxamide
CAS 712347-86-9C18H16N2O2
Methyl 2-{[(5-phenyl-3-isoxazolyl)carbonyl]amino}benzoate chemical structure, C18H14N2O4, CAS 712347-88-1
Methyl 2-{[(5-phenyl-3-isoxazolyl)carbonyl]amino}benzoate
CAS 712347-88-1C18H14N2O4
5-Phenyl-N-[3-(trifluoromethyl)phenyl]-1,2-oxazole-3-carboxamide chemical structure, C17H11F3N2O2, CAS 712347-89-2
5-Phenyl-N-[3-(trifluoromethyl)phenyl]-1,2-oxazole-3-carboxamide
CAS 712347-89-2C17H11F3N2O2
N-(4-Bromophenyl)-5-phenyl-1,2-oxazole-3-carboxamide chemical structure, C16H11BrN2O2, CAS 712347-90-5
N-(4-Bromophenyl)-5-phenyl-1,2-oxazole-3-carboxamide
CAS 712347-90-5C16H11BrN2O2
N-(2-Methylsulfanylphenyl)-5-phenyl-1,2-oxazole-3-carboxamide chemical structure, C17H14N2O2S, CAS 712347-91-6
N-(2-Methylsulfanylphenyl)-5-phenyl-1,2-oxazole-3-carboxamide
CAS 712347-91-6C17H14N2O2S
5-Phenyl-N-[4-(trifluoromethoxy)phenyl]-1,2-oxazole-3-carboxamide chemical structure, C17H11F3N2O3, CAS 712347-93-8
5-Phenyl-N-[4-(trifluoromethoxy)phenyl]-1,2-oxazole-3-carboxamide
CAS 712347-93-8C17H11F3N2O3
N-(3-Acetylphenyl)-5-(4-methylphenyl)-1,2-oxazole-3-carboxamide chemical structure, C19H16N2O3, CAS 712348-29-3
N-(3-Acetylphenyl)-5-(4-methylphenyl)-1,2-oxazole-3-carboxamide
CAS 712348-29-3C19H16N2O3
5-(2-Chlorophenyl)-N-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide chemical structure, C16H9ClF2N2O2, CAS 712348-41-9
5-(2-Chlorophenyl)-N-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
CAS 712348-41-9C16H9ClF2N2O2
N-(3-Hydroxyphenyl)-5-phenyl-1,2-oxazole-3-carboxamide chemical structure, C16H12N2O3, CAS 725697-66-5
N-(3-Hydroxyphenyl)-5-phenyl-1,2-oxazole-3-carboxamide
CAS 725697-66-5C16H12N2O3
N-(5-Chloro-2-hydroxyphenyl)-5-phenyl-1,2-oxazole-3-carboxamide chemical structure, C16H11ClN2O3, CAS 725697-67-6
N-(5-Chloro-2-hydroxyphenyl)-5-phenyl-1,2-oxazole-3-carboxamide
CAS 725697-67-6C16H11ClN2O3
N-(5-Bromo-2-hydroxyphenyl)-5-phenyl-1,2-oxazole-3-carboxamide chemical structure, C16H11BrN2O3, CAS 717831-31-7
N-(5-Bromo-2-hydroxyphenyl)-5-phenyl-1,2-oxazole-3-carboxamide
CAS 717831-31-7C16H11BrN2O3
N-(3,4-Dimethoxyphenyl)-5-phenyl-1,2-oxazole-3-carboxamide chemical structure, C18H16N2O4, CAS 725697-68-7
N-(3,4-Dimethoxyphenyl)-5-phenyl-1,2-oxazole-3-carboxamide
CAS 725697-68-7C18H16N2O4
N-(4-Chloro-2,5-dimethoxyphenyl)-5-phenyl-1,2-oxazole-3-carboxamide chemical structure, C18H15ClN2O4, CAS 712347-94-9
N-(4-Chloro-2,5-dimethoxyphenyl)-5-phenyl-1,2-oxazole-3-carboxamide
CAS 712347-94-9C18H15ClN2O4
N-(5-Chloro-2-methoxyphenyl)-5-phenyl-1,2-oxazole-3-carboxamide chemical structure, C17H13ClN2O3, CAS 725697-69-8
N-(5-Chloro-2-methoxyphenyl)-5-phenyl-1,2-oxazole-3-carboxamide
CAS 725697-69-8C17H13ClN2O3
N-(2-Bromo-4,6-difluorophenyl)-5-phenyl-1,2-oxazole-3-carboxamide chemical structure, C16H9BrF2N2O2, CAS 712347-95-0
N-(2-Bromo-4,6-difluorophenyl)-5-phenyl-1,2-oxazole-3-carboxamide
CAS 712347-95-0C16H9BrF2N2O2
5-Phenyl-N-(3,4,5-trimethoxyphenyl)-1,2-oxazole-3-carboxamide chemical structure, C19H18N2O5, CAS 712347-99-4
5-Phenyl-N-(3,4,5-trimethoxyphenyl)-1,2-oxazole-3-carboxamide
CAS 712347-99-4C19H18N2O5
N-(4-Methoxyphenyl)-5-phenyl-1,2-oxazole-3-carboxamide chemical structure, C17H14N2O3, CAS 725697-70-1
N-(4-Methoxyphenyl)-5-phenyl-1,2-oxazole-3-carboxamide
CAS 725697-70-1C17H14N2O3
N-(3-Hydroxyphenyl)-5-(4-methylphenyl)-1,2-oxazole-3-carboxamide chemical structure, C17H14N2O3, CAS 725697-93-8
N-(3-Hydroxyphenyl)-5-(4-methylphenyl)-1,2-oxazole-3-carboxamide
CAS 725697-93-8C17H14N2O3
N-(2-Hydroxy-5-methylphenyl)-5-(4-methylphenyl)-1,2-oxazole-3-carboxamide chemical structure, C18H16N2O3, CAS 717830-25-6
N-(2-Hydroxy-5-methylphenyl)-5-(4-methylphenyl)-1,2-oxazole-3-carboxamide
CAS 717830-25-6C18H16N2O3
N-(3,4-Dimethoxyphenyl)-5-(4-methylphenyl)-1,2-oxazole-3-carboxamide chemical structure, C19H18N2O4, CAS 717833-54-0
N-(3,4-Dimethoxyphenyl)-5-(4-methylphenyl)-1,2-oxazole-3-carboxamide
CAS 717833-54-0C19H18N2O4
N-(4-Chloro-2,5-dimethoxyphenyl)-5-(4-methylphenyl)-1,2-oxazole-3-carboxamide chemical structure, C19H17ClN2O4, CAS 717833-27-7
N-(4-Chloro-2,5-dimethoxyphenyl)-5-(4-methylphenyl)-1,2-oxazole-3-carboxamide
CAS 717833-27-7C19H17ClN2O4
N-(5-Chloro-2-methoxyphenyl)-5-(4-methylphenyl)-1,2-oxazole-3-carboxamide chemical structure, C18H15ClN2O3, CAS 725697-94-9
N-(5-Chloro-2-methoxyphenyl)-5-(4-methylphenyl)-1,2-oxazole-3-carboxamide
CAS 725697-94-9C18H15ClN2O3
5-(2-Chlorophenyl)-N-(3-hydroxyphenyl)-1,2-oxazole-3-carboxamide chemical structure, C16H11ClN2O3, CAS 725698-16-8
5-(2-Chlorophenyl)-N-(3-hydroxyphenyl)-1,2-oxazole-3-carboxamide
CAS 725698-16-8C16H11ClN2O3