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Murcko scaffold

Ring system with 3 rings and 19 atoms

17 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
17
With full pages
5
Scaffold SMILES

c1ccc(Nc2nccc(N3CCOCC3)n2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Nc2nccc(N3CCOCC3)n2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

2-N-(3-Fluorophenyl)-6-morpholin-4-yl-5-nitropyrimidine-2,4-diamine chemical structure, C14H15FN6O3, CAS 714930-55-9
2-N-(3-Fluorophenyl)-6-morpholin-4-yl-5-nitropyrimidine-2,4-diamine
CAS 714930-55-9C14H15FN6O3
6-(2,6-Dimethylmorpholin-4-yl)-5-nitro-2-N-phenylpyrimidine-2,4-diamine chemical structure, C16H20N6O3, CAS 714246-08-9
6-(2,6-Dimethylmorpholin-4-yl)-5-nitro-2-N-phenylpyrimidine-2,4-diamine
CAS 714246-08-9C16H20N6O3
2-N-Methyl-6-morpholin-4-yl-5-nitro-2-N-phenylpyrimidine-2,4-diamine chemical structure, C15H18N6O3, CAS 586993-58-0
2-N-Methyl-6-morpholin-4-yl-5-nitro-2-N-phenylpyrimidine-2,4-diamine
CAS 586993-58-0C15H18N6O3
6-(2,6-Dimethylmorpholin-4-yl)-N~2~-methyl-5-nitro-N~2~-phenylpyrimidine-2,4-diamine chemical structure, C17H22N6O3, CAS 713129-88-5
6-(2,6-Dimethylmorpholin-4-yl)-N~2~-methyl-5-nitro-N~2~-phenylpyrimidine-2,4-diamine
CAS 713129-88-5C17H22N6O3
2-N-(4-Methoxyphenyl)-6-morpholin-4-yl-5-nitropyrimidine-2,4-diamine chemical structure, C15H18N6O4, CAS 578003-25-5
2-N-(4-Methoxyphenyl)-6-morpholin-4-yl-5-nitropyrimidine-2,4-diamine
CAS 578003-25-5C15H18N6O4
2-N-(2-Fluorophenyl)-6-morpholin-4-yl-5-nitropyrimidine-2,4-diamine chemical structure, C14H15FN6O3, CAS 673498-15-2
2-N-(2-Fluorophenyl)-6-morpholin-4-yl-5-nitropyrimidine-2,4-diamine
CAS 673498-15-2C14H15FN6O3
2-N-(4-Ethoxyphenyl)-6-morpholin-4-yl-5-nitropyrimidine-2,4-diamine chemical structure, C16H20N6O4, CAS 714288-67-2
2-N-(4-Ethoxyphenyl)-6-morpholin-4-yl-5-nitropyrimidine-2,4-diamine
CAS 714288-67-2C16H20N6O4
2-Methoxy-N-(4-((4-methyl-6-morpholinopyrimidin-2-yl)amino)phenyl)acetamide chemical structure, C18H23N5O3, CAS 923121-25-9
2-Methoxy-N-(4-((4-methyl-6-morpholinopyrimidin-2-yl)amino)phenyl)acetamide
CAS 923121-25-9C18H23N5O3
N-(4-((4-Methyl-6-morpholinopyrimidin-2-yl)amino)phenyl)isobutyramide chemical structure, C19H25N5O2, CAS 946369-92-2
N-(4-((4-Methyl-6-morpholinopyrimidin-2-yl)amino)phenyl)isobutyramide
CAS 946369-92-2C19H25N5O2
3-Methyl-N-(4-((4-methyl-6-morpholinopyrimidin-2-yl)amino)phenyl)butanamide chemical structure, C20H27N5O2, CAS 946245-78-9
3-Methyl-N-(4-((4-methyl-6-morpholinopyrimidin-2-yl)amino)phenyl)butanamide
CAS 946245-78-9C20H27N5O2
N-(4-{[4-Methyl-6-(morpholin-4-yl)pyrimidin-2-yl]amino}phenyl)pentanamide chemical structure, C20H27N5O2, CAS 946295-71-2
N-(4-{[4-Methyl-6-(morpholin-4-yl)pyrimidin-2-yl]amino}phenyl)pentanamide
CAS 946295-71-2C20H27N5O2
N-(3-Fluorophenyl)-4-methyl-6-(morpholin-4-yl)-5-nitropyrimidin-2-amine chemical structure, C15H16FN5O3, CAS 1203112-67-7
N-(3-Fluorophenyl)-4-methyl-6-(morpholin-4-yl)-5-nitropyrimidin-2-amine
CAS 1203112-67-7C15H16FN5O3
Ethyl 4-((4-methyl-6-morpholino-5-nitropyrimidin-2-yl)amino)benzoate chemical structure, C18H21N5O5, CAS 1202980-24-2
Ethyl 4-((4-methyl-6-morpholino-5-nitropyrimidin-2-yl)amino)benzoate
CAS 1202980-24-2C18H21N5O5
N-{4-[(Difluoromethyl)sulfanyl]phenyl}-4-methyl-6-(morpholin-4-yl)-5-nitropyrimidin-2-amine chemical structure, C16H17F2N5O3S, CAS 1210695-30-9
N-{4-[(Difluoromethyl)sulfanyl]phenyl}-4-methyl-6-(morpholin-4-yl)-5-nitropyrimidin-2-amine
CAS 1210695-30-9C16H17F2N5O3S
N-(2,4-Dimethylphenyl)-4-methyl-6-(morpholin-4-yl)-5-nitropyrimidin-2-amine chemical structure, C17H21N5O3, CAS 1203226-65-6
N-(2,4-Dimethylphenyl)-4-methyl-6-(morpholin-4-yl)-5-nitropyrimidin-2-amine
CAS 1203226-65-6C17H21N5O3
N-(2,4-Dimethoxyphenyl)-4-methyl-6-(morpholin-4-yl)-5-nitropyrimidin-2-amine chemical structure, C17H21N5O5, CAS 1203205-72-4
N-(2,4-Dimethoxyphenyl)-4-methyl-6-(morpholin-4-yl)-5-nitropyrimidin-2-amine
CAS 1203205-72-4C17H21N5O5
N1-(4-Methyl-6-morpholinopyrimidin-2-yl)benzene-1,4-diamine chemical structure, C15H19N5O, CAS 1706431-98-2
N1-(4-Methyl-6-morpholinopyrimidin-2-yl)benzene-1,4-diamine
CAS 1706431-98-2C15H19N5O