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Murcko scaffold

Ring system with 3 rings and 16 atoms

21 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
21
With full pages
5
Scaffold SMILES

O=c1ccc2cnn(-c3ccccc3)c2o1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1ccc2cnn(-c3ccccc3)c2o1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 21 of 21 chemicals

N,4-dimethyl-6-oxo-1-phenylpyrano[2,3-c]pyrazole-3-carboxamide chemical structure, C15H13N3O3, CAS 81292-28-6
N,4-dimethyl-6-oxo-1-phenylpyrano[2,3-c]pyrazole-3-carboxamide
CAS 81292-28-6C15H13N3O3
1-(3-Chlorophenyl)-3,4-dimethylpyrano[2,3-c]pyrazol-6(1H)-one chemical structure, C14H11ClN2O2, CAS 96138-46-4
1-(3-Chlorophenyl)-3,4-dimethylpyrano[2,3-c]pyrazol-6(1H)-one
CAS 96138-46-4C14H11ClN2O2
1-(4-Bromophenyl)-3,4-dimethylpyrano[2,3-c]pyrazol-6(1H)-one chemical structure, C14H11BrN2O2, CAS 155297-20-4
1-(4-Bromophenyl)-3,4-dimethylpyrano[2,3-c]pyrazol-6(1H)-one
CAS 155297-20-4C14H11BrN2O2
1-(2,5-Dichlorophenyl)-3,4-dimethylpyrano[2,3-c]pyrazol-6(1H)-one chemical structure, C14H10Cl2N2O2, CAS 312621-02-6
1-(2,5-Dichlorophenyl)-3,4-dimethylpyrano[2,3-c]pyrazol-6(1H)-one
CAS 312621-02-6C14H10Cl2N2O2
1-(3,4-Dimethylphenyl)-3,4-dimethylpyrano[2,3-c]pyrazol-6(1H)-one chemical structure, C16H16N2O2, CAS 339218-72-3
1-(3,4-Dimethylphenyl)-3,4-dimethylpyrano[2,3-c]pyrazol-6(1H)-one
CAS 339218-72-3C16H16N2O2
1-(4-Chlorophenyl)-3,4-dimethylpyrano[2,3-c]pyrazol-6(1H)-one chemical structure, C14H11ClN2O2, CAS 74169-54-3
1-(4-Chlorophenyl)-3,4-dimethylpyrano[2,3-c]pyrazol-6(1H)-one
CAS 74169-54-3C14H11ClN2O2
3,4-Dimethyl-1-phenylpyrano[2,3-c]pyrazol-6(1H)-one chemical structure, C14H12N2O2, CAS 74169-52-1
3,4-Dimethyl-1-phenylpyrano[2,3-c]pyrazol-6(1H)-one
CAS 74169-52-1C14H12N2O2
1-(3,5-Dichlorophenyl)-3,4-dimethylpyrano[2,3-c]pyrazol-6(1H)-one chemical structure, C14H10Cl2N2O2, CAS 353502-64-4
1-(3,5-Dichlorophenyl)-3,4-dimethylpyrano[2,3-c]pyrazol-6(1H)-one
CAS 353502-64-4C14H10Cl2N2O2
3-(3,4-Dimethyl-6-oxo-6H-pyrano[2,3-c]pyrazol-1-yl)-benzoic acid chemical structure, C15H12N2O4, CAS 354557-58-7
3-(3,4-Dimethyl-6-oxo-6H-pyrano[2,3-c]pyrazol-1-yl)-benzoic acid
CAS 354557-58-7C15H12N2O4
3,4-Dimethyl-1-(4-methylphenyl)pyrano[2,3-c]pyrazol-6-one chemical structure, C15H14N2O2, CAS 74169-53-2
3,4-Dimethyl-1-(4-methylphenyl)pyrano[2,3-c]pyrazol-6-one
CAS 74169-53-2C15H14N2O2
1-(4-Methoxyphenyl)-3,4-dimethylpyrano[2,3-c]pyrazol-6(1H)-one chemical structure, C15H14N2O3, CAS 74169-55-4
1-(4-Methoxyphenyl)-3,4-dimethylpyrano[2,3-c]pyrazol-6(1H)-one
CAS 74169-55-4C15H14N2O3
5-Chloro-3,4-dimethyl-1-phenylpyrano[2,3-c]pyrazol-6-one chemical structure, C14H11ClN2O2, CAS 85094-37-7
5-Chloro-3,4-dimethyl-1-phenylpyrano[2,3-c]pyrazol-6-one
CAS 85094-37-7C14H11ClN2O2
3,4-Dimethyl-1-(4-nitrophenyl)pyrano[2,3-c]pyrazol-6(1H)-one chemical structure, C14H11N3O4, CAS 74169-56-5
3,4-Dimethyl-1-(4-nitrophenyl)pyrano[2,3-c]pyrazol-6(1H)-one
CAS 74169-56-5C14H11N3O4
Pyrano[2,3-c]pyrazol-6(1H)-one, 3-methyl-1-phenyl-4-propyl- chemical structure, C16H16N2O2, CAS 219766-70-8
Pyrano[2,3-c]pyrazol-6(1H)-one, 3-methyl-1-phenyl-4-propyl-
CAS 219766-70-8C16H16N2O2
1-(4-Fluorophenyl)-3,4-dimethylpyrano[2,3-c]pyrazol-6(1H)-one chemical structure, C14H11FN2O2, CAS 74169-57-6
1-(4-Fluorophenyl)-3,4-dimethylpyrano[2,3-c]pyrazol-6(1H)-one
CAS 74169-57-6C14H11FN2O2
4-(3,4-Dimethyl-6-oxopyrano[2,3-c]pyrazol-1-yl)benzenesulfonic acid chemical structure, C14H12N2O5S, CAS 676246-99-4
4-(3,4-Dimethyl-6-oxopyrano[2,3-c]pyrazol-1-yl)benzenesulfonic acid
CAS 676246-99-4C14H12N2O5S
Ethyl 3-methyl-6-oxo-1-phenyl-1,6-dihydropyrano[2,3-c]pyrazole-5-carboxylate chemical structure, C16H14N2O4, CAS 74414-00-9
Ethyl 3-methyl-6-oxo-1-phenyl-1,6-dihydropyrano[2,3-c]pyrazole-5-carboxylate
CAS 74414-00-9C16H14N2O4
1-(2-Chlorophenyl)-3,4-dimethylpyrano[2,3-c]pyrazol-6(1H)-one chemical structure, C14H11ClN2O2, CAS 85094-16-2
1-(2-Chlorophenyl)-3,4-dimethylpyrano[2,3-c]pyrazol-6(1H)-one
CAS 85094-16-2C14H11ClN2O2
5-Bromo-3,4-dimethyl-1-phenylpyrano[2,3-c]pyrazol-6(1H)-one chemical structure, C14H11BrN2O2, CAS 74169-59-8
5-Bromo-3,4-dimethyl-1-phenylpyrano[2,3-c]pyrazol-6(1H)-one
CAS 74169-59-8C14H11BrN2O2
3,4,5-Trimethyl-1-phenylpyrano[2,3-c]pyrazol-6(1H)-one chemical structure, C15H14N2O2, CAS 353287-46-4
3,4,5-Trimethyl-1-phenylpyrano[2,3-c]pyrazol-6(1H)-one
CAS 353287-46-4C15H14N2O2
1,6-Dihydro-3-methyl-6-oxo-1-phenylpyrano[2,3-c]pyrazole-5-carbonitrile chemical structure, C14H9N3O2, CAS 74413-97-1
1,6-Dihydro-3-methyl-6-oxo-1-phenylpyrano[2,3-c]pyrazole-5-carbonitrile
CAS 74413-97-1C14H9N3O2