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Murcko scaffold

Ring system with 3 rings and 18 atoms

9 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
9
With full pages
4
Scaffold SMILES

O=C(Nc1ccccc1)c1ccc2c(c1)CCN2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)c1ccc2c(c1)CCN2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

N-(4-Ethylphenyl)-1-(methylsulfonyl)-5-indolinecarboxamide chemical structure, C18H20N2O3S, CAS 662158-67-0
N-(4-Ethylphenyl)-1-(methylsulfonyl)-5-indolinecarboxamide
CAS 662158-67-0C18H20N2O3S
1-(Methylsulfonyl)-N-phenyl-5-indolinecarboxamide chemical structure, C16H16N2O3S, CAS 662158-65-8
1-(Methylsulfonyl)-N-phenyl-5-indolinecarboxamide
CAS 662158-65-8C16H16N2O3S
N-(4-Fluorophenyl)-1-(methylsulfonyl)-2,3-dihydro-1H-indole-5-carboxamide chemical structure, C16H15FN2O3S, CAS 799259-26-0
N-(4-Fluorophenyl)-1-(methylsulfonyl)-2,3-dihydro-1H-indole-5-carboxamide
CAS 799259-26-0C16H15FN2O3S
N-(3-Methylphenyl)-1-methylsulfonyl-2,3-dihydroindole-5-carboxamide chemical structure, C17H18N2O3S, CAS 799259-41-9
N-(3-Methylphenyl)-1-methylsulfonyl-2,3-dihydroindole-5-carboxamide
CAS 799259-41-9C17H18N2O3S
N-(2,5-Dichlorophenyl)-1-methylsulfonyl-2,3-dihydroindole-5-carboxamide chemical structure, C16H14Cl2N2O3S, CAS 712319-45-4
N-(2,5-Dichlorophenyl)-1-methylsulfonyl-2,3-dihydroindole-5-carboxamide
CAS 712319-45-4C16H14Cl2N2O3S
N-Methyl-1-methylsulfonyl-N-phenyl-2,3-dihydroindole-5-carboxamide chemical structure, C17H18N2O3S, CAS 727671-00-3
N-Methyl-1-methylsulfonyl-N-phenyl-2,3-dihydroindole-5-carboxamide
CAS 727671-00-3C17H18N2O3S
1-Acetyl-N-(3-chlorophenyl)indoline-5-carboxamide chemical structure, C17H15ClN2O2, CAS 1242934-00-4
1-Acetyl-N-(3-chlorophenyl)indoline-5-carboxamide
CAS 1242934-00-4C17H15ClN2O2
1H-Indole-5-carboxamide,N-(3-ethoxyphenyl)-2,3-dihydro- chemical structure, C17H18N2O2, CAS 1182914-87-9
1H-Indole-5-carboxamide,N-(3-ethoxyphenyl)-2,3-dihydro-
CAS 1182914-87-9C17H18N2O2
1H-Indole-5-carboxamide,2,3-dihydro-N-(2-methoxy-4-methylphenyl)- chemical structure, C17H18N2O2, CAS 1183855-63-1
1H-Indole-5-carboxamide,2,3-dihydro-N-(2-methoxy-4-methylphenyl)-
CAS 1183855-63-1C17H18N2O2