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Murcko scaffold

Ring system with 4 rings and 25 atoms

565 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
565
With full pages
14
Scaffold SMILES

O=C(NCC1CCCCC1)OCC1c2ccccc2-c2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCC1CCCCC1)OCC1c2ccccc2-c2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 385 to 432 of 565 chemicals

2-[3-Cyclohexyl-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanamido]butanoic acid chemical structure, C28H34N2O5, CAS 2171703-90-3
2-[3-Cyclohexyl-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanamido]butanoic acid
CAS 2171703-90-3C28H34N2O5
(2S)-2-({2-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)butanoic acid chemical structure, C27H32N2O5, CAS 2171376-14-8
(2S)-2-({2-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)butanoic acid
CAS 2171376-14-8C27H32N2O5
(2S)-3-({1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)-2-hydroxypropanoic acid chemical structure, C26H30N2O6, CAS 2171241-45-3
(2S)-3-({1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)-2-hydroxypropanoic acid
CAS 2171241-45-3C26H30N2O6
3-[3-Cyclohexyl-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanamido]-2-hydroxypropanoic acid chemical structure, C27H32N2O6, CAS 2172024-01-8
3-[3-Cyclohexyl-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanamido]-2-hydroxypropanoic acid
CAS 2172024-01-8C27H32N2O6
(3R)-3-({2-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)butanoic acid chemical structure, C27H32N2O5, CAS 2171339-80-1
(3R)-3-({2-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)butanoic acid
CAS 2171339-80-1C27H32N2O5
3-({1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)pentanoic acid chemical structure, C28H34N2O5, CAS 2171976-79-5
3-({1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)pentanoic acid
CAS 2171976-79-5C28H34N2O5
3-({1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)-2-hydroxypropanoic acid chemical structure, C26H30N2O6, CAS 2171814-67-6
3-({1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)-2-hydroxypropanoic acid
CAS 2171814-67-6C26H30N2O6
4-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)-2-methylbut-2-enoic acid chemical structure, C28H32N2O5, CAS 2172615-61-9
4-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)-2-methylbut-2-enoic acid
CAS 2172615-61-9C28H32N2O5
2-(1-{3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}-N-propylformamido)acetic acid chemical structure, C28H34N2O5, CAS 2171881-45-9
2-(1-{3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}-N-propylformamido)acetic acid
CAS 2171881-45-9C28H34N2O5
4-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)pentanoic acid chemical structure, C28H34N2O5, CAS 2172092-36-1
4-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)pentanoic acid
CAS 2172092-36-1C28H34N2O5
4-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)-3-methylbutanoic acid chemical structure, C28H34N2O5, CAS 2172483-54-2
4-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)-3-methylbutanoic acid
CAS 2172483-54-2C28H34N2O5
3-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)-2-methylbutanoic acid chemical structure, C28H34N2O5, CAS 2172483-59-7
3-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)-2-methylbutanoic acid
CAS 2172483-59-7C28H34N2O5
4-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)-2-hydroxybutanoic acid chemical structure, C27H32N2O6, CAS 2172483-66-6
4-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)-2-hydroxybutanoic acid
CAS 2172483-66-6C27H32N2O6
2-[({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)oxy]propanoic acid chemical structure, C26H30N2O6, CAS 2171933-97-2
2-[({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)oxy]propanoic acid
CAS 2171933-97-2C26H30N2O6
2-{[2-({3-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)ethyl]sulfanyl}acetic acid chemical structure, C27H32N2O5S, CAS 2171918-99-1
2-{[2-({3-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)ethyl]sulfanyl}acetic acid
CAS 2171918-99-1C27H32N2O5S
(2R)-2-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)propanoic acid chemical structure, C26H30N2O5, CAS 2648935-63-9
(2R)-2-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)propanoic acid
CAS 2648935-63-9C26H30N2O5
2-({1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)-3-hydroxy-2-methylpropanoic acid chemical structure, C27H32N2O6, CAS 2172572-22-2
2-({1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)-3-hydroxy-2-methylpropanoic acid
CAS 2172572-22-2C27H32N2O6
(2R)-2-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)butanoic acid chemical structure, C27H32N2O5, CAS 2171424-35-2
(2R)-2-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)butanoic acid
CAS 2171424-35-2C27H32N2O5
(2S)-2-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)butanoic acid chemical structure, C27H32N2O5, CAS 2171393-87-4
(2S)-2-({3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)butanoic acid
CAS 2171393-87-4C27H32N2O5
(2S)-2-(1-{3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}-N-methylformamido)propanoic acid chemical structure, C27H32N2O5, CAS 2648935-77-5
(2S)-2-(1-{3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}-N-methylformamido)propanoic acid
CAS 2648935-77-5C27H32N2O5
4-({1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)-2-methylbut-2-enoic acid chemical structure, C28H32N2O5, CAS 2172608-96-5
4-({1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)-2-methylbut-2-enoic acid
CAS 2172608-96-5C28H32N2O5
(3S)-3-({1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)butanoic acid chemical structure, C27H32N2O5, CAS 2171197-78-5
(3S)-3-({1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)butanoic acid
CAS 2171197-78-5C27H32N2O5
(2S)-2-({2-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)-4-hydroxybutanoic acid chemical structure, C27H32N2O6, CAS 2648937-81-7
(2S)-2-({2-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)-4-hydroxybutanoic acid
CAS 2648937-81-7C27H32N2O6
1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-4,4-dimethylcyclohexane-1-carboxylic acid chemical structure, C25H29NO4, CAS 2138025-29-1
1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-4,4-dimethylcyclohexane-1-carboxylic acid
CAS 2138025-29-1C25H29NO4