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Murcko scaffold

Ring system with 3 rings and 18 atoms

6 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
6
With full pages
4
Scaffold SMILES

c1ccc(-c2cncc(-c3cccnc3)c2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(-c2cncc(-c3cccnc3)c2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

Mmv-048 chemical structure, C18H14F3N3O2S, CAS 1314883-11-8
Mmv-048
CAS 1314883-11-8C18H14F3N3O2S
PF-06260933 dihydrochloride chemical structure, C16H15Cl3N4, CAS 1883548-86-4
PF-06260933 dihydrochloride
CAS 1883548-86-4C16H15Cl3N4
5-(4-Chlorophenyl)-[3,3'-bipyridine]-6,6'-diamine chemical structure, C16H13ClN4, CAS 1811510-56-1
5-(4-Chlorophenyl)-[3,3'-bipyridine]-6,6'-diamine
CAS 1811510-56-1C16H13ClN4
6'-Amino-4'-ethyl-5'-(4-hydroxyphenyl)-N-methyl-[3,3'-bipyridine]-6-carboxamide chemical structure, C20H20N4O2, CAS 2009273-71-4
6'-Amino-4'-ethyl-5'-(4-hydroxyphenyl)-N-methyl-[3,3'-bipyridine]-6-carboxamide
CAS 2009273-71-4C20H20N4O2
PF-06758955 Hydrochloride chemical structure, C20H19Cl2N3O3, CAS 1538637-10-3
PF-06758955 Hydrochloride
CAS 1538637-10-3C20H19Cl2N3O3
Ethyl 2-[[5-[6-amino-5-(4-chlorophenyl)-3-pyridinyl]-2-pyridinyl]oxy]-2-methylpropanoate chemical structure, C22H22ClN3O3, CAS 2007920-57-0
Ethyl 2-[[5-[6-amino-5-(4-chlorophenyl)-3-pyridinyl]-2-pyridinyl]oxy]-2-methylpropanoate
CAS 2007920-57-0C22H22ClN3O3