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Murcko scaffold

Ring system with 3 rings and 18 atoms

20 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 18
Chemicals: 20
With full pages: 3

Scaffold SMILES

O=C(Nc1ccccc1)c1ccc2[nH]cnc2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C(Nc1ccccc1)c1ccc2[nH]cnc2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 20 of 20 chemicals

Benzimidazol-5-yl-N-(2,3-dimethylphenyl)carboxamide chemical structure, C16H15N3O, CAS 446834-56-6

Benzimidazol-5-yl-N-(2,3-dimethylphenyl)carboxamide

CAS 446834-56-6C₁₆H₁₅N₃O

1-Ethyl-2-methyl-N-phenylbenzimidazole-5-carboxamide chemical structure, C17H17N3O, CAS 299927-14-3

1-Ethyl-2-methyl-N-phenylbenzimidazole-5-carboxamide

CAS 299927-14-3C₁₇H₁₇N₃O

N-[4-(Trifluoromethoxy)phenyl]-3H-benzimidazole-5-carboxamide chemical structure, C15H10F3N3O2, CAS 830350-75-9

N-[4-(Trifluoromethoxy)phenyl]-3H-benzimidazole-5-carboxamide

CAS 830350-75-9C₁₅H₁₀F₃N₃O₂

N-(2,4-Dimethoxyphenyl)-3H-benzimidazole-5-carboxamide chemical structure, C16H15N3O3, CAS 446834-52-2

N-(2,4-Dimethoxyphenyl)-3H-benzimidazole-5-carboxamide

CAS 446834-52-2C₁₆H₁₅N₃O₃

1H-1,3-Benzimidazole-6-carboxamide, N-(3-fluorophenyl)- chemical structure, C14H10FN3O, CAS 851171-65-8

1H-1,3-Benzimidazole-6-carboxamide, N-(3-fluorophenyl)-

CAS 851171-65-8C₁₄H₁₀FN₃O

N-(3,4-Difluorophenyl)-1H-benzimidazole-6-carboxamide chemical structure, C14H9F2N3O, CAS 728028-81-7

N-(3,4-Difluorophenyl)-1H-benzimidazole-6-carboxamide

CAS 728028-81-7C₁₄H₉F₂N₃O

Agn-PC-00aipw chemical structure, C19H22N4O, CAS 884330-18-1

CAS 884330-18-1C₁₉H₂₂N₄O

N-(2,4-Dichlorophenyl)-1H-1,3-benzodiazole-5-carboxamide chemical structure, C14H9Cl2N3O, CAS 880853-77-0

N-(2,4-Dichlorophenyl)-1H-1,3-benzodiazole-5-carboxamide

CAS 880853-77-0C₁₄H₉Cl₂N₃O

4-(5-Benzimidazolylcarbonylamino)phenylacetic acid chemical structure, C16H13N3O3, CAS 162046-54-0

4-(5-Benzimidazolylcarbonylamino)phenylacetic acid

CAS 162046-54-0C₁₆H₁₃N₃O₃

N-[4-(Acetylamino)phenyl]-2-methyl-1H-benzimidazole-6-carboxamide chemical structure, C17H16N4O2, CAS 1015590-78-9

N-[4-(Acetylamino)phenyl]-2-methyl-1H-benzimidazole-6-carboxamide

CAS 1015590-78-9C₁₇H₁₆N₄O₂

3-(1H-1,3-Benzodiazole-5-amido)benzoic acid chemical structure, C15H11N3O3, CAS 1016513-35-1

3-(1H-1,3-Benzodiazole-5-amido)benzoic acid

CAS 1016513-35-1C₁₅H₁₁N₃O₃

N,4-Dimethyl-N-(2-nitrophenyl)-2-propyl-1H-benzimidazole-6-carboxamide chemical structure, C19H20N4O3, CAS 1098100-89-0

N,4-Dimethyl-N-(2-nitrophenyl)-2-propyl-1H-benzimidazole-6-carboxamide

CAS 1098100-89-0C₁₉H₂₀N₄O₃

2-Methyl-N-[3-(trifluoromethyl)phenyl]-1H-benzimidazole-6-carboxamide chemical structure, C16H12F3N3O, CAS 1574309-69-5

2-Methyl-N-[3-(trifluoromethyl)phenyl]-1H-benzimidazole-6-carboxamide

CAS 1574309-69-5C₁₆H₁₂F₃N₃O

2-Methyl-N-(3,4,5-trimethoxyphenyl)-1H-benzimidazole-6-carboxamide chemical structure, C18H19N3O4, CAS 1574477-13-6

2-Methyl-N-(3,4,5-trimethoxyphenyl)-1H-benzimidazole-6-carboxamide

CAS 1574477-13-6C₁₈H₁₉N₃O₄

N-[3-(Acetylamino)phenyl]-2-methyl-1H-benzimidazole-6-carboxamide chemical structure, C17H16N4O2, CAS 1574471-35-4

N-[3-(Acetylamino)phenyl]-2-methyl-1H-benzimidazole-6-carboxamide

CAS 1574471-35-4C₁₇H₁₆N₄O₂

N-[4-Chloro-2-(trifluoromethyl)phenyl]-1H-1,3-benzodiazole-5-carboxamide chemical structure, C15H9ClF3N3O, CAS 1428379-02-5

N-[4-Chloro-2-(trifluoromethyl)phenyl]-1H-1,3-benzodiazole-5-carboxamide

CAS 1428379-02-5C₁₅H₉ClF₃N₃O

N-(4-Carbamoylphenyl)-2-methyl-1H-benzimidazole-6-carboxamide chemical structure, C16H14N4O2, CAS 1574405-20-1

N-(4-Carbamoylphenyl)-2-methyl-1H-benzimidazole-6-carboxamide

CAS 1574405-20-1C₁₆H₁₄N₄O₂

(R)-7-Bromo-N-[4-(chlorodifluoromethoxy)phenyl]-2-(difluoromethyl)-1-(1-hydroxypropan-2-yl)-1H-benzo[d]imidazole-5-carboxamide chemical structure, C19H15BrClF4N3O3, CAS 2412969-27-6

(R)-7-Bromo-N-[4-(chlorodifluoromethoxy)phenyl]-2-(difluoromethyl)-1-(1-hydroxypropan-2-yl)-1H-benzo[d]imidazole-5-carboxamide

CAS 2412969-27-6C₁₉H₁₅BrClF₄N₃O₃

7-Bromo-N-[4-(chlorodifluoromethoxy)phenyl]-1-isopropyl-1H-benzo[D]imidazole-5-carboxamide chemical structure, C18H15BrClF2N3O2, CAS 2412972-50-8

7-Bromo-N-[4-(chlorodifluoromethoxy)phenyl]-1-isopropyl-1H-benzo[D]imidazole-5-carboxamide

CAS 2412972-50-8C₁₈H₁₅BrClF₂N₃O₂

N-(2-Aminophenyl)-N,7-dimethyl-2-propyl-3H-benzimidazole-5-carboxamide chemical structure, C19H22N4O, CAS 1860008-29-2

N-(2-Aminophenyl)-N,7-dimethyl-2-propyl-3H-benzimidazole-5-carboxamide

CAS 1860008-29-2C₁₉H₂₂N₄O