CompoundList
Sign in
Murcko scaffold

Pyrazolo(1,5-a)pyrimidine scaffold

2,195 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
9
Chemicals
2,195
With full pages
244
Scaffold SMILES

c1cnc2ccnn2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Pyrazolo(1,5-a)pyrimidine page
Murcko scaffold c1cnc2ccnn2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 961 to 1,008 of 2,195 chemicals

7-Isopropyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-5-carboxylic acid chemical structure, C11H10F3N3O2, CAS 1784657-90-4
7-Isopropyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-5-carboxylic acid
CAS 1784657-90-4C11H10F3N3O2
5-Isopropyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-7-carboxylic acid chemical structure, C11H10F3N3O2, CAS 1795426-66-2
5-Isopropyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-7-carboxylic acid
CAS 1795426-66-2C11H10F3N3O2
6-Methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid chemical structure, C9H6F3N3O2, CAS 1790365-86-4
6-Methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid
CAS 1790365-86-4C9H6F3N3O2
Methyl 7-isopropyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-5-carboxylate chemical structure, C12H12F3N3O2, CAS 1798723-27-9
Methyl 7-isopropyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-5-carboxylate
CAS 1798723-27-9C12H12F3N3O2
7-(Difluoromethyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidine chemical structure, C9H9F2N3, CAS 1795186-93-4
7-(Difluoromethyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidine
CAS 1795186-93-4C9H9F2N3
3-(Trifluoromethyl)pyrazolo[1,5-a]pyrimidine-6-carboxylic acid chemical structure, C8H4F3N3O2, CAS 1779124-56-9
3-(Trifluoromethyl)pyrazolo[1,5-a]pyrimidine-6-carboxylic acid
CAS 1779124-56-9C8H4F3N3O2
3-(Trifluoromethyl)pyrazolo[1,5-a]pyrimidin-6-amine chemical structure, C7H5F3N4, CAS 1713160-74-7
3-(Trifluoromethyl)pyrazolo[1,5-a]pyrimidin-6-amine
CAS 1713160-74-7C7H5F3N4
6-Bromo-3-tert-butylpyrazolo[1,5-a]pyrimidine chemical structure, C10H12BrN3, CAS 1379349-89-9
6-Bromo-3-tert-butylpyrazolo[1,5-a]pyrimidine
CAS 1379349-89-9C10H12BrN3
2-Isopropylpyrazolo[1,5-a]pyrimidin-6-amine hydrochloride chemical structure, C9H13ClN4, CAS 1707358-53-9
2-Isopropylpyrazolo[1,5-a]pyrimidin-6-amine hydrochloride
CAS 1707358-53-9C9H13ClN4
6-Bromo-3-isopropylpyrazolo[1,5-a]pyrimidine chemical structure, C9H10BrN3, CAS 1379344-54-3
6-Bromo-3-isopropylpyrazolo[1,5-a]pyrimidine
CAS 1379344-54-3C9H10BrN3
6-Bromo-3-ethylpyrazolo[1,5-a]pyrimidine chemical structure, C8H8BrN3, CAS 1379302-38-1
6-Bromo-3-ethylpyrazolo[1,5-a]pyrimidine
CAS 1379302-38-1C8H8BrN3
3-Ethylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid chemical structure, C9H9N3O2, CAS 1779128-22-1
3-Ethylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid
CAS 1779128-22-1C9H9N3O2
3-Ethylpyrazolo[1,5-a]pyrimidin-6-amine chemical structure, C8H10N4, CAS 1707713-94-7
3-Ethylpyrazolo[1,5-a]pyrimidin-6-amine
CAS 1707713-94-7C8H10N4
Pyrazolo[1,5-a]pyrimidine-3-carbothioamide chemical structure, C7H6N4S, CAS 1421263-27-5
Pyrazolo[1,5-a]pyrimidine-3-carbothioamide
CAS 1421263-27-5C7H6N4S
6-Bromo-3-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine chemical structure, C7H3BrF3N3, CAS 1378877-15-6
6-Bromo-3-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
CAS 1378877-15-6C7H3BrF3N3
2-(5,7-Dichloropyrazolo[1,5-a]pyrimidin-6-yl)acetaldehyde chemical structure, C8H5Cl2N3O, CAS 1956331-50-2
2-(5,7-Dichloropyrazolo[1,5-a]pyrimidin-6-yl)acetaldehyde
CAS 1956331-50-2C8H5Cl2N3O
6-Formylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid chemical structure, C8H5N3O3, CAS 1356016-23-3
6-Formylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid
CAS 1356016-23-3C8H5N3O3
Methyl 2-(2-bromo-7-chloro-5-methylpyrazolo[1,5-a]pyrimidin-6-yl)acetate chemical structure, C10H9BrClN3O2, CAS 1364597-19-2
Methyl 2-(2-bromo-7-chloro-5-methylpyrazolo[1,5-a]pyrimidin-6-yl)acetate
CAS 1364597-19-2C10H9BrClN3O2
Methyl 2-(2-bromo-7-chloro-5-methylpyrazolo[1,5-a]pyrimidin-6-yl)-2-tert-butoxyacetate chemical structure, C14H17BrClN3O3, CAS 1364597-27-2
Methyl 2-(2-bromo-7-chloro-5-methylpyrazolo[1,5-a]pyrimidin-6-yl)-2-tert-butoxyacetate
CAS 1364597-27-2C14H17BrClN3O3
Ethyl 5,7-dichloropyrazolo[1,5-a]pyrimidine-2-carboxylate chemical structure, C9H7Cl2N3O2, CAS 1232224-62-2
Ethyl 5,7-dichloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS 1232224-62-2C9H7Cl2N3O2
Ethyl 7-chloro-6-(2-ethoxy-2-oxoethyl)-5-methylpyrazolo[1,5-a]pyrimidine-2-carboxylate chemical structure, C14H16ClN3O4, CAS 1423742-66-8
Ethyl 7-chloro-6-(2-ethoxy-2-oxoethyl)-5-methylpyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS 1423742-66-8C14H16ClN3O4
Ethyl 6-(2-ethoxy-2-oxoacetyl)-7-iodo-5-methylpyrazolo[1,5-a]pyrimidine-2-carboxylate chemical structure, C14H14IN3O5, CAS 1423742-69-1
Ethyl 6-(2-ethoxy-2-oxoacetyl)-7-iodo-5-methylpyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS 1423742-69-1C14H14IN3O5
Allyl 2-amino-6-fluoro-pyrazolo[1,5-a]pyrimidine-3-carboxylate chemical structure, C10H9FN4O2, CAS 1613191-76-6
Allyl 2-amino-6-fluoro-pyrazolo[1,5-a]pyrimidine-3-carboxylate
CAS 1613191-76-6C10H9FN4O2
2-Amino-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxylic acid chemical structure, C7H5FN4O2, CAS 1613191-77-7
2-Amino-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxylic acid
CAS 1613191-77-7C7H5FN4O2