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Murcko scaffold

Pyrazolo(1,5-a)pyrimidine scaffold

2,195 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
9
Chemicals
2,195
With full pages
244
Scaffold SMILES

c1cnc2ccnn2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Pyrazolo(1,5-a)pyrimidine page
Murcko scaffold c1cnc2ccnn2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1,345 to 1,392 of 2,195 chemicals

5-Bromo-3-methylpyrazolo[1,5-a]pyrimidine chemical structure, C7H6BrN3, CAS 2741426-71-9
5-Bromo-3-methylpyrazolo[1,5-a]pyrimidine
CAS 2741426-71-9C7H6BrN3
Methyl 2-bromo-7-methylpyrazolo[1,5-a]pyrimidine-5-carboxylate chemical structure, C9H8BrN3O2, CAS 2171317-69-2
Methyl 2-bromo-7-methylpyrazolo[1,5-a]pyrimidine-5-carboxylate
CAS 2171317-69-2C9H8BrN3O2
2-Bromo-7-methylpyrazolo[1,5-a]pyrimidine-5-carboxylic acid chemical structure, C8H6BrN3O2, CAS 2171314-06-8
2-Bromo-7-methylpyrazolo[1,5-a]pyrimidine-5-carboxylic acid
CAS 2171314-06-8C8H6BrN3O2
2-Bromo-7-ethylpyrazolo[1,5-a]pyrimidine-5-carboxylic acid chemical structure, C9H8BrN3O2, CAS 2035418-54-1
2-Bromo-7-ethylpyrazolo[1,5-a]pyrimidine-5-carboxylic acid
CAS 2035418-54-1C9H8BrN3O2
Methyl 2-bromo-7-chloropyrazolo[1,5-A]pyrimidine-5-carboxylate chemical structure, C8H5BrClN3O2, CAS 2035422-57-0
Methyl 2-bromo-7-chloropyrazolo[1,5-A]pyrimidine-5-carboxylate
CAS 2035422-57-0C8H5BrClN3O2
5-Chloro-2-fluoropyrazolo[1,5-a]pyrimidine chemical structure, C6H3ClFN3, CAS 2227206-65-5
5-Chloro-2-fluoropyrazolo[1,5-a]pyrimidine
CAS 2227206-65-5C6H3ClFN3
7-Bromo-5-methylpyrazolo[1,5-a]pyrimidine chemical structure, C7H6BrN3, CAS 2089157-30-0
7-Bromo-5-methylpyrazolo[1,5-a]pyrimidine
CAS 2089157-30-0C7H6BrN3
N-(7-Chloropyrazolo[1,5-A]pyrimidin-5-yl)acetamide chemical structure, C8H7ClN4O, CAS 2092894-49-8
N-(7-Chloropyrazolo[1,5-A]pyrimidin-5-yl)acetamide
CAS 2092894-49-8C8H7ClN4O
7-Chloro-3-(1-methylethyl)pyrazolo[1,5-a]pyrimidine chemical structure, C9H10ClN3, CAS 1384055-37-1
7-Chloro-3-(1-methylethyl)pyrazolo[1,5-a]pyrimidine
CAS 1384055-37-1C9H10ClN3
Ethyl 7-chloro-3-fluoro-pyrazolo[1,5-a]pyrimidine-5-carboxylate chemical structure, C9H7ClFN3O2, CAS 2253880-34-9
Ethyl 7-chloro-3-fluoro-pyrazolo[1,5-a]pyrimidine-5-carboxylate
CAS 2253880-34-9C9H7ClFN3O2
7-Chloro-2-fluoropyrazolo[1,5-a]pyrimidine chemical structure, C6H3ClFN3, CAS 2306273-00-5
7-Chloro-2-fluoropyrazolo[1,5-a]pyrimidine
CAS 2306273-00-5C6H3ClFN3
2-Fluoropyrazolo[1,5-a]pyrimidine-6-carboxylic acid chemical structure, C7H4FN3O2, CAS 2168274-16-4
2-Fluoropyrazolo[1,5-a]pyrimidine-6-carboxylic acid
CAS 2168274-16-4C7H4FN3O2
Ethyl 5,7-dimethyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate chemical structure, C12H12F3N3O2, CAS 915157-99-2
Ethyl 5,7-dimethyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate
CAS 915157-99-2C12H12F3N3O2
2-Fluoropyrazolo[1,5-a]pyrimidin-6-amine chemical structure, C6H5FN4, CAS 2169039-27-2
2-Fluoropyrazolo[1,5-a]pyrimidin-6-amine
CAS 2169039-27-2C6H5FN4
5-Bromo-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid chemical structure, C8H6BrN3O2, CAS 2306278-39-5
5-Bromo-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid
CAS 2306278-39-5C8H6BrN3O2
6-Chloro-3-iodopyrazolo[1,5-a]pyrimidine chemical structure, C6H3ClIN3, CAS 2306264-38-8
6-Chloro-3-iodopyrazolo[1,5-a]pyrimidine
CAS 2306264-38-8C6H3ClIN3
2-Amino-6-bromopyrazolo[1,5-a]pyrimidine-3-carbonitrile chemical structure, C7H4BrN5, CAS 2219419-53-9
2-Amino-6-bromopyrazolo[1,5-a]pyrimidine-3-carbonitrile
CAS 2219419-53-9C7H4BrN5
N-{2,5-Dimethylpyrazolo[1,5-a]pyrimidin-7-yl}prop-2-enamide chemical structure, C11H12N4O, CAS 2270918-55-1
N-{2,5-Dimethylpyrazolo[1,5-a]pyrimidin-7-yl}prop-2-enamide
CAS 2270918-55-1C11H12N4O
7-((tert-Butoxycarbonyl)(methyl)amino)-5-chloropyrazolo[1,5-a]pyrimidine-3-carboxylic acid chemical structure, C13H15ClN4O4, CAS 2271470-66-5
7-((tert-Butoxycarbonyl)(methyl)amino)-5-chloropyrazolo[1,5-a]pyrimidine-3-carboxylic acid
CAS 2271470-66-5C13H15ClN4O4
Ethyl 7-(bis(tert-butoxycarbonyl)amino)-5-chloro-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxylate chemical structure, C20H27ClN4O6, CAS 2271471-16-8
Ethyl 7-(bis(tert-butoxycarbonyl)amino)-5-chloro-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxylate
CAS 2271471-16-8C20H27ClN4O6
Ethyl 7-((tert-butoxycarbonyl)(methyl)amino)-5-chloropyrazolo[1,5-a]pyrimidine-3-carboxylate chemical structure, C15H19ClN4O4, CAS 2271470-65-4
Ethyl 7-((tert-butoxycarbonyl)(methyl)amino)-5-chloropyrazolo[1,5-a]pyrimidine-3-carboxylate
CAS 2271470-65-4C15H19ClN4O4
Ethyl 5-chloro-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxylate chemical structure, C10H11ClN4O2, CAS 2271470-64-3
Ethyl 5-chloro-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxylate
CAS 2271470-64-3C10H11ClN4O2
5-Chloro-3-iodo-N-methylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C7H6ClIN4, CAS 2271471-69-1
5-Chloro-3-iodo-N-methylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 2271471-69-1C7H6ClIN4
tert-Butyl (5-chloro-3-ethynylpyrazolo[1,5-a]pyrimidin-7-yl)(methyl)carbamate chemical structure, C14H15ClN4O2, CAS 2271471-72-6
tert-Butyl (5-chloro-3-ethynylpyrazolo[1,5-a]pyrimidin-7-yl)(methyl)carbamate
CAS 2271471-72-6C14H15ClN4O2