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Murcko scaffold

Pyrazolo(1,5-a)pyrimidine scaffold

2,195 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
9
Chemicals
2,195
With full pages
244
Scaffold SMILES

c1cnc2ccnn2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Pyrazolo(1,5-a)pyrimidine page
Murcko scaffold c1cnc2ccnn2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1,393 to 1,440 of 2,195 chemicals

3-Bromo-7-chloro-5-methyl-2-(trifluoromethyl)pyrazolo[1,5-A]pyrimidine chemical structure, C8H4BrClF3N3, CAS 2089650-35-9
3-Bromo-7-chloro-5-methyl-2-(trifluoromethyl)pyrazolo[1,5-A]pyrimidine
CAS 2089650-35-9C8H4BrClF3N3
3-Bromo-N-methyl-pyrazolo[1,5-a]pyrimidin-5-amine chemical structure, C7H7BrN4, CAS 2750707-91-4
3-Bromo-N-methyl-pyrazolo[1,5-a]pyrimidin-5-amine
CAS 2750707-91-4C7H7BrN4
3-Fluoro-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid chemical structure, C8H3F4N3O2, CAS 2334457-06-4
3-Fluoro-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid
CAS 2334457-06-4C8H3F4N3O2
6-Bromo-3-iodo-2-methylpyrazolo[1,5-a]pyrimidine hydrochloride chemical structure, C7H6BrClIN3, CAS 2305254-62-8
6-Bromo-3-iodo-2-methylpyrazolo[1,5-a]pyrimidine hydrochloride
CAS 2305254-62-8C7H6BrClIN3
N-(Cyanomethyl)-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide chemical structure, C10H9N5O, CAS 2361720-45-6
N-(Cyanomethyl)-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide
CAS 2361720-45-6C10H9N5O
N-(6-Methylpyrazolo[1,5-a]pyrimidin-3-yl)acrylamide chemical structure, C10H10N4O, CAS 2305392-96-3
N-(6-Methylpyrazolo[1,5-a]pyrimidin-3-yl)acrylamide
CAS 2305392-96-3C10H10N4O
Ethyl 3-bromo-7-chloro-2-methyl-pyrazolo[1,5-a]pyrimidine-5-carboxylate chemical structure, C10H9BrClN3O2, CAS 2107098-14-4
Ethyl 3-bromo-7-chloro-2-methyl-pyrazolo[1,5-a]pyrimidine-5-carboxylate
CAS 2107098-14-4C10H9BrClN3O2
Ethyl 2-(7-chloro-3-iodo-2-methyl-pyrazolo[1,5-a]pyrimidin-5-yl)acetate chemical structure, C11H11ClIN3O2, CAS 2365242-88-0
Ethyl 2-(7-chloro-3-iodo-2-methyl-pyrazolo[1,5-a]pyrimidin-5-yl)acetate
CAS 2365242-88-0C11H11ClIN3O2
Ethyl 7-chloro-2-methyl-pyrazolo[1,5-a]pyrimidine-5-carboxylate chemical structure, C10H10ClN3O2, CAS 2365242-43-7
Ethyl 7-chloro-2-methyl-pyrazolo[1,5-a]pyrimidine-5-carboxylate
CAS 2365242-43-7C10H10ClN3O2
Ethyl 7-chloro-3-iodo-2-methyl-pyrazolo[1,5-a]pyrimidine-5-carboxylate chemical structure, C10H9ClIN3O2, CAS 2365242-44-8
Ethyl 7-chloro-3-iodo-2-methyl-pyrazolo[1,5-a]pyrimidine-5-carboxylate
CAS 2365242-44-8C10H9ClIN3O2
Ethyl 2-(7-chloro-2-methyl-pyrazolo[1,5-a]pyrimidin-5-yl)acetate chemical structure, C11H12ClN3O2, CAS 2365242-87-9
Ethyl 2-(7-chloro-2-methyl-pyrazolo[1,5-a]pyrimidin-5-yl)acetate
CAS 2365242-87-9C11H12ClN3O2
3-Bromo-5-(difluoromethyl)pyrazolo[1,5-a]pyrimidine chemical structure, C7H4BrF2N3, CAS 2366185-17-1
3-Bromo-5-(difluoromethyl)pyrazolo[1,5-a]pyrimidine
CAS 2366185-17-1C7H4BrF2N3
3-Iodo-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine chemical structure, C7H3F3IN3, CAS 2366185-18-2
3-Iodo-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
CAS 2366185-18-2C7H3F3IN3
7-{[(tert-Butoxy)carbonyl]amino}-5-methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid chemical structure, C13H16N4O4, CAS 2580209-35-2
7-{[(tert-Butoxy)carbonyl]amino}-5-methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid
CAS 2580209-35-2C13H16N4O4
6-(Trifluoromethyl)pyrazolo[1,5-a]pyrimidine chemical structure, C7H4F3N3, CAS 2418692-63-2
6-(Trifluoromethyl)pyrazolo[1,5-a]pyrimidine
CAS 2418692-63-2C7H4F3N3
2-Ethylpyrazolo[1,5-a]pyrimidine chemical structure, C8H9N3, CAS 78562-33-1
2-Ethylpyrazolo[1,5-a]pyrimidine
CAS 78562-33-1C8H9N3
(S)-2-Chloro-7-(1-methoxyethyl)pyrazolo[1,5-a]pyrimidin-6-amine chemical structure, C9H11ClN4O, CAS 2254644-66-9
(S)-2-Chloro-7-(1-methoxyethyl)pyrazolo[1,5-a]pyrimidin-6-amine
CAS 2254644-66-9C9H11ClN4O
Ethyl 5-ethylpyrazolo[1,5-a]pyrimidine-3-carboxylate chemical structure, C11H13N3O2, CAS 1823257-39-1
Ethyl 5-ethylpyrazolo[1,5-a]pyrimidine-3-carboxylate
CAS 1823257-39-1C11H13N3O2
2-Bromopyrazolo[1,5-A]pyrimidin-5-amine chemical structure, C6H5BrN4, CAS 2738608-15-4
2-Bromopyrazolo[1,5-A]pyrimidin-5-amine
CAS 2738608-15-4C6H5BrN4
3-Bromopyrazolo[1,5-a]pyrimidin-5-amine chemical structure, C6H5BrN4, CAS 2413085-89-7
3-Bromopyrazolo[1,5-a]pyrimidin-5-amine
CAS 2413085-89-7C6H5BrN4
2-Iodo-5-methylpyrazolo[1,5-a]pyrimidine chemical structure, C7H6IN3, CAS 2171314-03-5
2-Iodo-5-methylpyrazolo[1,5-a]pyrimidine
CAS 2171314-03-5C7H6IN3
Pyrazolo[1,5-a]pyrimidin-7-amine, 5-chloro-3-(1-methylethyl)- chemical structure, C9H11ClN4, CAS 2654077-75-3
Pyrazolo[1,5-a]pyrimidin-7-amine, 5-chloro-3-(1-methylethyl)-
CAS 2654077-75-3C9H11ClN4
2-Bromo-5-methylpyrazolo[1,5-a]pyrimidine chemical structure, C7H6BrN3, CAS 2171314-14-8
2-Bromo-5-methylpyrazolo[1,5-a]pyrimidine
CAS 2171314-14-8C7H6BrN3
2,7-Dibromopyrazolo[1,5-a]pyrimidine chemical structure, C6H3Br2N3, CAS 2375204-75-2
2,7-Dibromopyrazolo[1,5-a]pyrimidine
CAS 2375204-75-2C6H3Br2N3