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Murcko scaffold

Pyrazolo(1,5-a)pyrimidine scaffold

2,195 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
9
Chemicals
2,195
With full pages
244
Scaffold SMILES

c1cnc2ccnn2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Pyrazolo(1,5-a)pyrimidine page
Murcko scaffold c1cnc2ccnn2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1,681 to 1,728 of 2,195 chemicals

6-(3-Bromoprop-1-en-2-yl)pyrazolo[1,5-a]pyrimidine chemical structure, C9H8BrN3, CAS 2229163-32-8
6-(3-Bromoprop-1-en-2-yl)pyrazolo[1,5-a]pyrimidine
CAS 2229163-32-8C9H8BrN3
2,2-Difluoro-2-{pyrazolo[1,5-a]pyrimidin-6-yl}ethan-1-ol chemical structure, C8H7F2N3O, CAS 2228967-31-3
2,2-Difluoro-2-{pyrazolo[1,5-a]pyrimidin-6-yl}ethan-1-ol
CAS 2228967-31-3C8H7F2N3O
2,2-Difluoro-2-{pyrazolo[1,5-a]pyrimidin-2-yl}ethan-1-amine chemical structure, C8H8F2N4, CAS 2228306-81-6
2,2-Difluoro-2-{pyrazolo[1,5-a]pyrimidin-2-yl}ethan-1-amine
CAS 2228306-81-6C8H8F2N4
2,2-Difluoro-2-{pyrazolo[1,5-a]pyrimidin-2-yl}ethan-1-ol chemical structure, C8H7F2N3O, CAS 2228801-93-0
2,2-Difluoro-2-{pyrazolo[1,5-a]pyrimidin-2-yl}ethan-1-ol
CAS 2228801-93-0C8H7F2N3O
2,2-Difluoro-3-{pyrazolo[1,5-a]pyrimidin-2-yl}propan-1-amine chemical structure, C9H10F2N4, CAS 2228568-53-2
2,2-Difluoro-3-{pyrazolo[1,5-a]pyrimidin-2-yl}propan-1-amine
CAS 2228568-53-2C9H10F2N4
2,2,2-Trifluoro-1-{pyrazolo[1,5-a]pyrimidin-2-yl}ethan-1-amine chemical structure, C8H7F3N4, CAS 2229269-34-3
2,2,2-Trifluoro-1-{pyrazolo[1,5-a]pyrimidin-2-yl}ethan-1-amine
CAS 2229269-34-3C8H7F3N4
3,3-Difluoro-3-{pyrazolo[1,5-a]pyrimidin-2-yl}propan-1-ol chemical structure, C9H9F2N3O, CAS 2229520-34-5
3,3-Difluoro-3-{pyrazolo[1,5-a]pyrimidin-2-yl}propan-1-ol
CAS 2229520-34-5C9H9F2N3O
3,3-Difluoro-3-{pyrazolo[1,5-a]pyrimidin-6-yl}propan-1-ol chemical structure, C9H9F2N3O, CAS 2228304-73-0
3,3-Difluoro-3-{pyrazolo[1,5-a]pyrimidin-6-yl}propan-1-ol
CAS 2228304-73-0C9H9F2N3O
1,1,1-Trifluoro-3-{pyrazolo[1,5-a]pyrimidin-2-yl}propan-2-amine chemical structure, C9H9F3N4, CAS 2228135-85-9
1,1,1-Trifluoro-3-{pyrazolo[1,5-a]pyrimidin-2-yl}propan-2-amine
CAS 2228135-85-9C9H9F3N4
1,1-Difluoro-2-{pyrazolo[1,5-a]pyrimidin-2-yl}propan-2-amine chemical structure, C9H10F2N4, CAS 2229181-93-3
1,1-Difluoro-2-{pyrazolo[1,5-a]pyrimidin-2-yl}propan-2-amine
CAS 2229181-93-3C9H10F2N4
1,1-Difluoro-3-{pyrazolo[1,5-a]pyrimidin-6-yl}propan-2-amine chemical structure, C9H10F2N4, CAS 2228657-94-9
1,1-Difluoro-3-{pyrazolo[1,5-a]pyrimidin-6-yl}propan-2-amine
CAS 2228657-94-9C9H10F2N4
2,2,2-Trifluoro-1-{pyrazolo[1,5-a]pyrimidin-6-yl}ethan-1-one chemical structure, C8H4F3N3O, CAS 2229230-77-5
2,2,2-Trifluoro-1-{pyrazolo[1,5-a]pyrimidin-6-yl}ethan-1-one
CAS 2229230-77-5C8H4F3N3O
2,2-Difluoro-1-{pyrazolo[1,5-a]pyrimidin-2-yl}ethan-1-one chemical structure, C8H5F2N3O, CAS 2228661-81-0
2,2-Difluoro-1-{pyrazolo[1,5-a]pyrimidin-2-yl}ethan-1-one
CAS 2228661-81-0C8H5F2N3O
{Pyrazolo[1,5-a]pyrimidin-6-yl}methyl sulfamate chemical structure, C7H8N4O3S, CAS 2228833-13-2
{Pyrazolo[1,5-a]pyrimidin-6-yl}methyl sulfamate
CAS 2228833-13-2C7H8N4O3S
3-{Pyrazolo[1,5-a]pyrimidin-2-yl}propane-1-thiol chemical structure, C9H11N3S, CAS 2229186-85-8
3-{Pyrazolo[1,5-a]pyrimidin-2-yl}propane-1-thiol
CAS 2229186-85-8C9H11N3S
2-Chloro-1-{pyrazolo[1,5-a]pyrimidin-6-yl}ethan-1-ol chemical structure, C8H8ClN3O, CAS 2229547-67-3
2-Chloro-1-{pyrazolo[1,5-a]pyrimidin-6-yl}ethan-1-ol
CAS 2229547-67-3C8H8ClN3O
2-{Pyrazolo[1,5-a]pyrimidin-2-yl}ethan-1-ol chemical structure, C8H9N3O, CAS 2228675-56-5
2-{Pyrazolo[1,5-a]pyrimidin-2-yl}ethan-1-ol
CAS 2228675-56-5C8H9N3O
2-{Pyrazolo[1,5-a]pyrimidin-2-yl}propanenitrile chemical structure, C9H8N4, CAS 2109911-18-2
2-{Pyrazolo[1,5-a]pyrimidin-2-yl}propanenitrile
CAS 2109911-18-2C9H8N4
2-Amino-3-methyl-3-{pyrazolo[1,5-a]pyrimidin-6-yl}butanoic acid chemical structure, C11H14N4O2, CAS 2228095-46-1
2-Amino-3-methyl-3-{pyrazolo[1,5-a]pyrimidin-6-yl}butanoic acid
CAS 2228095-46-1C11H14N4O2
(3R)-3-Hydroxy-3-{pyrazolo[1,5-a]pyrimidin-6-yl}propanoic acid chemical structure, C9H9N3O3, CAS 2227796-69-0
(3R)-3-Hydroxy-3-{pyrazolo[1,5-a]pyrimidin-6-yl}propanoic acid
CAS 2227796-69-0C9H9N3O3
2-(1-Bromopropan-2-yl)pyrazolo[1,5-a]pyrimidine chemical structure, C9H10BrN3, CAS 2229013-06-1
2-(1-Bromopropan-2-yl)pyrazolo[1,5-a]pyrimidine
CAS 2229013-06-1C9H10BrN3
2-(3-Bromopropyl)pyrazolo[1,5-a]pyrimidine chemical structure, C9H10BrN3, CAS 2228882-19-5
2-(3-Bromopropyl)pyrazolo[1,5-a]pyrimidine
CAS 2228882-19-5C9H10BrN3
4-{Pyrazolo[1,5-a]pyrimidin-2-yl}butan-1-amine chemical structure, C10H14N4, CAS 2229224-65-9
4-{Pyrazolo[1,5-a]pyrimidin-2-yl}butan-1-amine
CAS 2229224-65-9C10H14N4
1-{Pyrazolo[1,5-a]pyrimidin-6-yl}propan-2-ol chemical structure, C9H11N3O, CAS 2228200-66-4
1-{Pyrazolo[1,5-a]pyrimidin-6-yl}propan-2-ol
CAS 2228200-66-4C9H11N3O