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Murcko scaffold

Pyrazolo(1,5-a)pyrimidine scaffold

2,195 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
9
Chemicals
2,195
With full pages
244
Scaffold SMILES

c1cnc2ccnn2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Pyrazolo(1,5-a)pyrimidine page
Murcko scaffold c1cnc2ccnn2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1,729 to 1,776 of 2,195 chemicals

3-Hydroxy-3-{pyrazolo[1,5-a]pyrimidin-2-yl}propanenitrile chemical structure, C9H8N4O, CAS 2228459-08-1
3-Hydroxy-3-{pyrazolo[1,5-a]pyrimidin-2-yl}propanenitrile
CAS 2228459-08-1C9H8N4O
2-Methoxy-2-{pyrazolo[1,5-a]pyrimidin-6-yl}propan-1-amine chemical structure, C10H14N4O, CAS 2228839-44-7
2-Methoxy-2-{pyrazolo[1,5-a]pyrimidin-6-yl}propan-1-amine
CAS 2228839-44-7C10H14N4O
3-{Pyrazolo[1,5-a]pyrimidin-2-yloxy}propan-1-amine chemical structure, C9H12N4O, CAS 2228394-11-2
3-{Pyrazolo[1,5-a]pyrimidin-2-yloxy}propan-1-amine
CAS 2228394-11-2C9H12N4O
3-{Pyrazolo[1,5-a]pyrimidin-6-yl}propanal chemical structure, C9H9N3O, CAS 2229492-04-8
3-{Pyrazolo[1,5-a]pyrimidin-6-yl}propanal
CAS 2229492-04-8C9H9N3O
(2S)-4-{Pyrazolo[1,5-a]pyrimidin-2-yl}butan-2-ol chemical structure, C10H13N3O, CAS 2227806-55-3
(2S)-4-{Pyrazolo[1,5-a]pyrimidin-2-yl}butan-2-ol
CAS 2227806-55-3C10H13N3O
O-(2-{Pyrazolo[1,5-a]pyrimidin-6-yl}ethyl)hydroxylamine chemical structure, C8H10N4O, CAS 2228532-30-5
O-(2-{Pyrazolo[1,5-a]pyrimidin-6-yl}ethyl)hydroxylamine
CAS 2228532-30-5C8H10N4O
1,1,1-Trifluoro-3-{pyrazolo[1,5-a]pyrimidin-6-yl}propan-2-amine chemical structure, C9H9F3N4, CAS 2228614-53-5
1,1,1-Trifluoro-3-{pyrazolo[1,5-a]pyrimidin-6-yl}propan-2-amine
CAS 2228614-53-5C9H9F3N4
tert-Butyl N-methyl-N-(1-oxo-2-{pyrazolo[1,5-a]pyrimidin-6-yl}propan-2-yl)carbamate chemical structure, C15H20N4O3, CAS 2229165-01-7
tert-Butyl N-methyl-N-(1-oxo-2-{pyrazolo[1,5-a]pyrimidin-6-yl}propan-2-yl)carbamate
CAS 2229165-01-7C15H20N4O3
tert-Butyl N-(2-oxo-1-{pyrazolo[1,5-a]pyrimidin-6-yl}ethyl)carbamate chemical structure, C13H16N4O3, CAS 2228243-43-2
tert-Butyl N-(2-oxo-1-{pyrazolo[1,5-a]pyrimidin-6-yl}ethyl)carbamate
CAS 2228243-43-2C13H16N4O3
(1R)-3-Amino-1-{pyrazolo[1,5-a]pyrimidin-6-yl}propan-1-ol chemical structure, C9H12N4O, CAS 2227703-44-6
(1R)-3-Amino-1-{pyrazolo[1,5-a]pyrimidin-6-yl}propan-1-ol
CAS 2227703-44-6C9H12N4O
{Pyrazolo[1,5-a]pyrimidin-2-yl}hydrazine chemical structure, C6H7N5, CAS 2229273-62-3
{Pyrazolo[1,5-a]pyrimidin-2-yl}hydrazine
CAS 2229273-62-3C6H7N5
(2S)-4-{Pyrazolo[1,5-a]pyrimidin-6-yl}butan-2-amine chemical structure, C10H14N4, CAS 2227822-61-7
(2S)-4-{Pyrazolo[1,5-a]pyrimidin-6-yl}butan-2-amine
CAS 2227822-61-7C10H14N4
2-{Pyrazolo[1,5-a]pyrimidin-6-yl}ethane-1-sulfonyl fluoride chemical structure, C8H8FN3O2S, CAS 2228732-16-7
2-{Pyrazolo[1,5-a]pyrimidin-6-yl}ethane-1-sulfonyl fluoride
CAS 2228732-16-7C8H8FN3O2S
4-{Pyrazolo[1,5-a]pyrimidin-2-yl}but-3-en-2-amine chemical structure, C10H12N4, CAS 2229653-86-3
4-{Pyrazolo[1,5-a]pyrimidin-2-yl}but-3-en-2-amine
CAS 2229653-86-3C10H12N4
(2R)-1-{Pyrazolo[1,5-a]pyrimidin-2-yl}propan-2-amine chemical structure, C9H12N4, CAS 2227860-30-0
(2R)-1-{Pyrazolo[1,5-a]pyrimidin-2-yl}propan-2-amine
CAS 2227860-30-0C9H12N4
6-Ethenylpyrazolo[1,5-a]pyrimidine chemical structure, C8H7N3, CAS 2228543-98-2
6-Ethenylpyrazolo[1,5-a]pyrimidine
CAS 2228543-98-2C8H7N3
2-(1-Bromo-2-methylpropan-2-yl)pyrazolo[1,5-a]pyrimidine chemical structure, C10H12BrN3, CAS 2228740-56-3
2-(1-Bromo-2-methylpropan-2-yl)pyrazolo[1,5-a]pyrimidine
CAS 2228740-56-3C10H12BrN3
6-(2-Azidoethyl)pyrazolo[1,5-a]pyrimidine chemical structure, C8H8N6, CAS 2229338-17-2
6-(2-Azidoethyl)pyrazolo[1,5-a]pyrimidine
CAS 2229338-17-2C8H8N6
(1S)-3-Amino-1-{pyrazolo[1,5-a]pyrimidin-2-yl}propan-1-ol chemical structure, C9H12N4O, CAS 2227669-48-7
(1S)-3-Amino-1-{pyrazolo[1,5-a]pyrimidin-2-yl}propan-1-ol
CAS 2227669-48-7C9H12N4O
{Pyrazolo[1,5-a]pyrimidin-2-yl}methanesulfonamide chemical structure, C7H8N4O2S, CAS 2228548-31-8
{Pyrazolo[1,5-a]pyrimidin-2-yl}methanesulfonamide
CAS 2228548-31-8C7H8N4O2S
2-Bromo-1-{pyrazolo[1,5-a]pyrimidin-6-yl}ethan-1-ol chemical structure, C8H8BrN3O, CAS 2229106-61-8
2-Bromo-1-{pyrazolo[1,5-a]pyrimidin-6-yl}ethan-1-ol
CAS 2229106-61-8C8H8BrN3O
6-(3-Chloroprop-1-en-2-yl)pyrazolo[1,5-a]pyrimidine chemical structure, C9H8ClN3, CAS 2228747-07-5
6-(3-Chloroprop-1-en-2-yl)pyrazolo[1,5-a]pyrimidine
CAS 2228747-07-5C9H8ClN3
(1S)-2-Amino-1-{pyrazolo[1,5-a]pyrimidin-6-yl}ethan-1-ol chemical structure, C8H10N4O, CAS 2227864-24-4
(1S)-2-Amino-1-{pyrazolo[1,5-a]pyrimidin-6-yl}ethan-1-ol
CAS 2227864-24-4C8H10N4O
(1S)-1-{Pyrazolo[1,5-a]pyrimidin-6-yl}ethan-1-ol chemical structure, C8H9N3O, CAS 2227863-64-9
(1S)-1-{Pyrazolo[1,5-a]pyrimidin-6-yl}ethan-1-ol
CAS 2227863-64-9C8H9N3O