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Murcko scaffold

2-(Thiazol-5-ylmethyl)isoindoline-1,3-dione scaffold

7 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
7
With full pages
3
Scaffold SMILES

O=C1c2ccccc2C(=O)N1Cc1cncs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(Thiazol-5-ylmethyl)isoindoline-1,3-dione page
Murcko scaffold O=C1c2ccccc2C(=O)N1Cc1cncs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

Methyl (5-((1,3-dioxoisoindolin-2-yl)methyl)thiazol-2-yl)carbamate chemical structure, C14H11N3O4S, CAS 540511-97-5
Methyl (5-((1,3-dioxoisoindolin-2-yl)methyl)thiazol-2-yl)carbamate
CAS 540511-97-5C14H11N3O4S
2-[(2-Chloro-1,3-thiazol-5-yl)methyl]-1H-isoindole-1,3(2H)-dione chemical structure, C12H7ClN2O2S, CAS 120740-09-2
2-[(2-Chloro-1,3-thiazol-5-yl)methyl]-1H-isoindole-1,3(2H)-dione
CAS 120740-09-2C12H7ClN2O2S
2-(Thiazol-5-ylmethyl)isoindoline-1,3-dione chemical structure, C12H8N2O2S, CAS 131052-45-4
2-(Thiazol-5-ylmethyl)isoindoline-1,3-dione
CAS 131052-45-4C12H8N2O2S
2-[(2-Bromo-4-methyl-1,3-thiazol-5-yl)methyl]-1H-isoindole-1,3(2H)-dione chemical structure, C13H9BrN2O2S, CAS 1151512-21-8
2-[(2-Bromo-4-methyl-1,3-thiazol-5-yl)methyl]-1H-isoindole-1,3(2H)-dione
CAS 1151512-21-8C13H9BrN2O2S
2-((2-Methylthiazol-5-yl)methyl)isoindoline-1,3-dione chemical structure, C13H10N2O2S, CAS 838892-96-9
2-((2-Methylthiazol-5-yl)methyl)isoindoline-1,3-dione
CAS 838892-96-9C13H10N2O2S
4-Fluoro-2-(thiazol-5-ylmethyl)isoindoline-1,3-dione chemical structure, C12H7FN2O2S, CAS 1381925-25-2
4-Fluoro-2-(thiazol-5-ylmethyl)isoindoline-1,3-dione
CAS 1381925-25-2C12H7FN2O2S
2-[(2-Bromo-1,3-thiazol-5-yl)methyl]-2,3-dihydro-1H-isoindole-1,3-dione chemical structure, C12H7BrN2O2S, CAS 917946-67-9
2-[(2-Bromo-1,3-thiazol-5-yl)methyl]-2,3-dihydro-1H-isoindole-1,3-dione
CAS 917946-67-9C12H7BrN2O2S