CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 16 atoms

12 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
12
With full pages
6
Scaffold SMILES

S=c1[nH]cc(C=C2N=c3ccccc3=N2)s1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold S=c1[nH]cc(C=C2N=c3ccccc3=N2)s1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

5-(1H-Benzimidazol-2-ylmethylene)-3-ethyl-2-thioxo-1,3-thiazolidin-4-one chemical structure, C13H11N3OS2, CAS 385377-43-5
5-(1H-Benzimidazol-2-ylmethylene)-3-ethyl-2-thioxo-1,3-thiazolidin-4-one
CAS 385377-43-5C13H11N3OS2
4-Thiazolidinone, 5-(1H-benzimidazol-2-ylmethylene)-2-thioxo- chemical structure, C11H7N3OS2, CAS 31409-56-0
4-Thiazolidinone, 5-(1H-benzimidazol-2-ylmethylene)-2-thioxo-
CAS 31409-56-0C11H7N3OS2
(Z)-6-(5-((1H-Benzo[d]imidazol-2-yl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)hexanoic acid chemical structure, C17H17N3O3S2, CAS 1164558-49-9
(Z)-6-(5-((1H-Benzo[d]imidazol-2-yl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)hexanoic acid
CAS 1164558-49-9C17H17N3O3S2
3-[(5Z)-5-(1H-Benzimidazol-2-ylmethylidene)-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]propanoic acid chemical structure, C14H11N3O3S2, CAS 854002-59-8
3-[(5Z)-5-(1H-Benzimidazol-2-ylmethylidene)-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]propanoic acid
CAS 854002-59-8C14H11N3O3S2
[(5Z)-5-(1H-Benzimidazol-2-ylmethylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]acetic acid chemical structure, C13H9N3O3S2, CAS 881561-42-8
[(5Z)-5-(1H-Benzimidazol-2-ylmethylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]acetic acid
CAS 881561-42-8C13H9N3O3S2
(Z)-4-(5-((1H-Benzo[d]imidazol-2-yl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)butanoic acid chemical structure, C15H13N3O3S2, CAS 461715-77-5
(Z)-4-(5-((1H-Benzo[d]imidazol-2-yl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)butanoic acid
CAS 461715-77-5C15H13N3O3S2
(Z)-5-((1H-Benzo[d]imidazol-2-yl)methylene)-3-methyl-2-thioxothiazolidin-4-one chemical structure, C12H9N3OS2, CAS 854002-63-4
(Z)-5-((1H-Benzo[d]imidazol-2-yl)methylene)-3-methyl-2-thioxothiazolidin-4-one
CAS 854002-63-4C12H9N3OS2
(Z)-2-(5-((1H-Benzo[d]imidazol-2-yl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)propanoic acid chemical structure, C14H11N3O3S2, CAS 854002-60-1
(Z)-2-(5-((1H-Benzo[d]imidazol-2-yl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)propanoic acid
CAS 854002-60-1C14H11N3O3S2
(Z)-2-(5-((1H-Benzo[d]imidazol-2-yl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)butanoic acid chemical structure, C15H13N3O3S2, CAS 854002-61-2
(Z)-2-(5-((1H-Benzo[d]imidazol-2-yl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)butanoic acid
CAS 854002-61-2C15H13N3O3S2
(Z)-2-(5-((1H-Benzo[d]imidazol-2-yl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)pentanoic acid chemical structure, C16H15N3O3S2, CAS 881561-48-4
(Z)-2-(5-((1H-Benzo[d]imidazol-2-yl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)pentanoic acid
CAS 881561-48-4C16H15N3O3S2
(Z)-2-(5-((1H-Benzo[d]imidazol-2-yl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)-3-methylbutanoic acid chemical structure, C16H15N3O3S2, CAS 854002-62-3
(Z)-2-(5-((1H-Benzo[d]imidazol-2-yl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)-3-methylbutanoic acid
CAS 854002-62-3C16H15N3O3S2
(Z)-2-(5-((1H-Benzo[d]imidazol-2-yl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)-4-(methylthio)butanoic acid chemical structure, C16H15N3O3S3, CAS 881561-54-2
(Z)-2-(5-((1H-Benzo[d]imidazol-2-yl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)-4-(methylthio)butanoic acid
CAS 881561-54-2C16H15N3O3S3