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Murcko scaffold

Ring system with 3 rings and 17 atoms

13 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
13
With full pages
3
Scaffold SMILES

O=C1c2ccccc2C(=O)N1Cc1cn[nH]c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1c2ccccc2C(=O)N1Cc1cn[nH]c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

2-((3,5-Dimethyl-1H-pyrazol-4-yl)methyl)isoindoline-1,3-dione chemical structure, C14H13N3O2, CAS 41935-25-5
2-((3,5-Dimethyl-1H-pyrazol-4-yl)methyl)isoindoline-1,3-dione
CAS 41935-25-5C14H13N3O2
4-[(1,3-Dioxoisoindol-2-yl)methyl]-N,N-diethyl-3,5-dimethylpyrazole-1-carboxamide chemical structure, C19H22N4O3, CAS 890604-38-3
4-[(1,3-Dioxoisoindol-2-yl)methyl]-N,N-diethyl-3,5-dimethylpyrazole-1-carboxamide
CAS 890604-38-3C19H22N4O3
4-[(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]-N,N,3,5-tetramethyl-1H-pyrazole-1-sulfonamide chemical structure, C16H18N4O4S, CAS 890604-48-5
4-[(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]-N,N,3,5-tetramethyl-1H-pyrazole-1-sulfonamide
CAS 890604-48-5C16H18N4O4S
4-[(1,3-Dioxoisoindol-2-yl)methyl]-N,N,3,5-tetramethylpyrazole-1-carboxamide chemical structure, C17H18N4O3, CAS 890604-44-1
4-[(1,3-Dioxoisoindol-2-yl)methyl]-N,N,3,5-tetramethylpyrazole-1-carboxamide
CAS 890604-44-1C17H18N4O3
2-((5-Methyl-1H-pyrazol-4-yl)methyl)isoindoline-1,3-dione chemical structure, C13H11N3O2, CAS 1028843-16-4
2-((5-Methyl-1H-pyrazol-4-yl)methyl)isoindoline-1,3-dione
CAS 1028843-16-4C13H11N3O2
2-((1,3,5-Trimethyl-1H-pyrazol-4-yl)methyl)isoindoline-1,3-dione chemical structure, C15H15N3O2, CAS 50699-17-7
2-((1,3,5-Trimethyl-1H-pyrazol-4-yl)methyl)isoindoline-1,3-dione
CAS 50699-17-7C15H15N3O2
4-Amino-2-((3,5-dimethyl-1H-pyrazol-4-yl)methyl)isoindoline-1,3-dione chemical structure, C14H14N4O2, CAS 50866-19-8
4-Amino-2-((3,5-dimethyl-1H-pyrazol-4-yl)methyl)isoindoline-1,3-dione
CAS 50866-19-8C14H14N4O2
4-Amino-2-{[1-(2-hydroxyethyl)-1H-pyrazol-4-yl]methyl}-2,3-dihydro-1H-isoindole-1,3-dione chemical structure, C14H14N4O3, CAS 1487397-72-7
4-Amino-2-{[1-(2-hydroxyethyl)-1H-pyrazol-4-yl]methyl}-2,3-dihydro-1H-isoindole-1,3-dione
CAS 1487397-72-7C14H14N4O3
5-Amino-2-((3,5-dimethyl-1H-pyrazol-4-yl)methyl)isoindoline-1,3-dione chemical structure, C14H14N4O2, CAS 41935-26-6
5-Amino-2-((3,5-dimethyl-1H-pyrazol-4-yl)methyl)isoindoline-1,3-dione
CAS 41935-26-6C14H14N4O2
N-(2-((3,5-Dimethyl-1H-pyrazol-4-yl)methyl)-1,3-dioxoisoindolin-5-yl)acetamide chemical structure, C16H16N4O3, CAS 50698-85-6
N-(2-((3,5-Dimethyl-1H-pyrazol-4-yl)methyl)-1,3-dioxoisoindolin-5-yl)acetamide
CAS 50698-85-6C16H16N4O3
N-(2-((3,5-Dimethyl-1H-pyrazol-4-yl)methyl)-1,3-dioxoisoindolin-4-yl)acetamide chemical structure, C16H16N4O3, CAS 50699-20-2
N-(2-((3,5-Dimethyl-1H-pyrazol-4-yl)methyl)-1,3-dioxoisoindolin-4-yl)acetamide
CAS 50699-20-2C16H16N4O3
N-(2-((3,5-Dimethyl-1H-pyrazol-4-yl)methyl)-1,3-dioxoisoindolin-5-yl)propionamide chemical structure, C17H18N4O3, CAS 50699-21-3
N-(2-((3,5-Dimethyl-1H-pyrazol-4-yl)methyl)-1,3-dioxoisoindolin-5-yl)propionamide
CAS 50699-21-3C17H18N4O3
N-(2-((3,5-Dimethyl-1H-pyrazol-4-yl)methyl)-1,3-dioxoisoindolin-4-yl)propionamide chemical structure, C17H18N4O3, CAS 50981-11-8
N-(2-((3,5-Dimethyl-1H-pyrazol-4-yl)methyl)-1,3-dioxoisoindolin-4-yl)propionamide
CAS 50981-11-8C17H18N4O3