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Murcko scaffold

2-(Oxolan-2-ylmethyl)isoindole-1,3-dione scaffold

7 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
7
With full pages
4
Scaffold SMILES

O=C1c2ccccc2C(=O)N1CC1CCCO1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(Oxolan-2-ylmethyl)isoindole-1,3-dione page
Murcko scaffold O=C1c2ccccc2C(=O)N1CC1CCCO1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

1,3-Dioxo-2-(tetrahydro-furan-2-ylmethyl)-2,3-dihydro-1H-isoindole-5-carboxylic acid chemical structure, C14H13NO5, CAS 312498-19-4
1,3-Dioxo-2-(tetrahydro-furan-2-ylmethyl)-2,3-dihydro-1H-isoindole-5-carboxylic acid
CAS 312498-19-4C14H13NO5
5-Nitro-2-(oxolan-2-ylmethyl)isoindole-1,3-dione chemical structure, C13H12N2O5, CAS 294891-39-7
5-Nitro-2-(oxolan-2-ylmethyl)isoindole-1,3-dione
CAS 294891-39-7C13H12N2O5
2-(Oxolan-2-ylmethyl)isoindole-1,3-dione chemical structure, C13H13NO3, CAS 26116-10-9
2-(Oxolan-2-ylmethyl)isoindole-1,3-dione
CAS 26116-10-9C13H13NO3
5-Amino-2-(tetrahydro-2-furanylmethyl)-1H-isoindole-1,3(2H)-dione chemical structure, C13H14N2O3, CAS 434297-53-7
5-Amino-2-(tetrahydro-2-furanylmethyl)-1H-isoindole-1,3(2H)-dione
CAS 434297-53-7C13H14N2O3
N-[1,3-Dioxo-2-(tetrahydrofuran-2-ylmethyl)-2,3-dihydro-1H-isoindol-5-yl]butanamide chemical structure, C17H20N2O4, CAS 899268-08-7
N-[1,3-Dioxo-2-(tetrahydrofuran-2-ylmethyl)-2,3-dihydro-1H-isoindol-5-yl]butanamide
CAS 899268-08-7C17H20N2O4
(E)-4-[[1,3-Dioxo-2-(oxolan-2-ylmethyl)isoindol-5-yl]amino]-4-oxobut-2-enoic acid chemical structure, C17H16N2O6, CAS 899269-35-3
(E)-4-[[1,3-Dioxo-2-(oxolan-2-ylmethyl)isoindol-5-yl]amino]-4-oxobut-2-enoic acid
CAS 899269-35-3C17H16N2O6
2-((5-(Hydroxymethyl)tetrahydrofuran-2-yl)methyl)isoindoline-1,3-dione chemical structure, C14H15NO4, CAS 2247618-96-6
2-((5-(Hydroxymethyl)tetrahydrofuran-2-yl)methyl)isoindoline-1,3-dione
CAS 2247618-96-6C14H15NO4