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Murcko scaffold

1-N-Cbz-3-pyrrolidinone scaffold

47 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
16
Chemicals
47
With full pages
6
Scaffold SMILES

O=C1CCN(C(=O)OCc2ccccc2)C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-N-Cbz-3-pyrrolidinone page
Murcko scaffold O=C1CCN(C(=O)OCc2ccccc2)C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 47 of 47 chemicals

1-N-Cbz-3-pyrrolidinone chemical structure, C12H13NO3, CAS 130312-02-6
1-N-Cbz-3-pyrrolidinone
CAS 130312-02-6C12H13NO3
1-[(Benzyloxy)carbonyl]-4-oxopyrrolidine-2-carboxylic acid chemical structure, C13H13NO5, CAS 105903-44-4
1-[(Benzyloxy)carbonyl]-4-oxopyrrolidine-2-carboxylic acid
CAS 105903-44-4C13H13NO5
Benzyl 2-(2-ethoxy-2-oxoethyl)-3-oxopyrrolidine-1-carboxylate chemical structure, C16H19NO5, CAS 219841-93-7
Benzyl 2-(2-ethoxy-2-oxoethyl)-3-oxopyrrolidine-1-carboxylate
CAS 219841-93-7C16H19NO5
N-Carbobenzyloxy-4-keto-L-proline chemical structure, C13H13NO5, CAS 64187-47-9
N-Carbobenzyloxy-4-keto-L-proline
CAS 64187-47-9C13H13NO5
Phenylmethyl 3-oxo-2-(2-propen-1-yl)-1-pyrrolidinecarboxylate chemical structure, C15H17NO3, CAS 776316-72-4
Phenylmethyl 3-oxo-2-(2-propen-1-yl)-1-pyrrolidinecarboxylate
CAS 776316-72-4C15H17NO3
1-Benzyl 2-methyl (2S)-4-oxopyrrolidine-1,2-dicarboxylate chemical structure, C14H15NO5, CAS 16217-15-5
1-Benzyl 2-methyl (2S)-4-oxopyrrolidine-1,2-dicarboxylate
CAS 16217-15-5C14H15NO5
1-Benzyl 2-(tert-butyl) (S)-4-oxopyrrolidine-1,2-dicarboxylate chemical structure, C17H21NO5, CAS 147489-27-8
1-Benzyl 2-(tert-butyl) (S)-4-oxopyrrolidine-1,2-dicarboxylate
CAS 147489-27-8C17H21NO5
1-Benzyl 2-methyl 3-oxopyrrolidine-1,2-dicarboxylate chemical structure, C14H15NO5, CAS 92249-27-9
1-Benzyl 2-methyl 3-oxopyrrolidine-1,2-dicarboxylate
CAS 92249-27-9C14H15NO5
1-Benzyl 2-ethyl 4-oxopyrrolidine-1,2-dicarboxylate chemical structure, C15H17NO5, CAS 182750-13-6
1-Benzyl 2-ethyl 4-oxopyrrolidine-1,2-dicarboxylate
CAS 182750-13-6C15H17NO5
Ethyl (S)-1-Cbz-4-oxopyrrolidine-2-carboxylate chemical structure, C15H17NO5, CAS 83507-89-5
Ethyl (S)-1-Cbz-4-oxopyrrolidine-2-carboxylate
CAS 83507-89-5C15H17NO5
1-Benzyl 2-ethyl 3-oxopyrrolidine-1,2-dicarboxylate chemical structure, C15H17NO5, CAS 51814-18-7
1-Benzyl 2-ethyl 3-oxopyrrolidine-1,2-dicarboxylate
CAS 51814-18-7C15H17NO5
1-Benzyl 3-ethyl 4-oxopyrrolidine-1,3-dicarboxylate chemical structure, C15H17NO5, CAS 51814-19-8
1-Benzyl 3-ethyl 4-oxopyrrolidine-1,3-dicarboxylate
CAS 51814-19-8C15H17NO5
Benzyl 2-methyl-4-oxopyrrolidine-1-carboxylate chemical structure, C13H15NO3, CAS 2169045-23-0
Benzyl 2-methyl-4-oxopyrrolidine-1-carboxylate
CAS 2169045-23-0C13H15NO3
(R)-1-((Benzyloxy)carbonyl)-4-oxopyrrolidine-2-carboxylic acid chemical structure, C13H13NO5, CAS 147226-04-8
(R)-1-((Benzyloxy)carbonyl)-4-oxopyrrolidine-2-carboxylic acid
CAS 147226-04-8C13H13NO5
1-Benzyl 2-methyl (2R)-4-oxopyrrolidine-1,2-dicarboxylate chemical structure, C14H15NO5, CAS 132431-11-9
1-Benzyl 2-methyl (2R)-4-oxopyrrolidine-1,2-dicarboxylate
CAS 132431-11-9C14H15NO5
N-Cbz-4-oxo-pyrrolidine-2-carboxylic acid tert-butyl ester chemical structure, C17H21NO5, CAS 1822429-73-1
N-Cbz-4-oxo-pyrrolidine-2-carboxylic acid tert-butyl ester
CAS 1822429-73-1C17H21NO5
1-Benzyl 3-ethyl 3-methyl-4-oxopyrrolidine-1,3-dicarboxylate chemical structure, C16H19NO5, CAS 309762-63-8
1-Benzyl 3-ethyl 3-methyl-4-oxopyrrolidine-1,3-dicarboxylate
CAS 309762-63-8C16H19NO5
Benzyl 3-cyano-4-oxopyrrolidine-1-carboxylate chemical structure, C13H12N2O3, CAS 1276125-30-4
Benzyl 3-cyano-4-oxopyrrolidine-1-carboxylate
CAS 1276125-30-4C13H12N2O3
Benzyl (2R)-2-methyl-4-oxo-pyrrolidine-1-carboxylate chemical structure, C13H15NO3, CAS 2227426-91-5
Benzyl (2R)-2-methyl-4-oxo-pyrrolidine-1-carboxylate
CAS 2227426-91-5C13H15NO3
Benzyl (2S)-2-ethyl-3-oxopyrrolidine-1-carboxylate chemical structure, C14H17NO3, CAS 1030899-87-6
Benzyl (2S)-2-ethyl-3-oxopyrrolidine-1-carboxylate
CAS 1030899-87-6C14H17NO3
Benzyl (2S)-2-methyl-3-oxopyrrolidine-1-carboxylate chemical structure, C13H15NO3, CAS 1030899-57-0
Benzyl (2S)-2-methyl-3-oxopyrrolidine-1-carboxylate
CAS 1030899-57-0C13H15NO3
Benzyl 3,3-dimethyl-4-oxopyrrolidine-1-carboxylate chemical structure, C14H17NO3, CAS 1152110-90-1
Benzyl 3,3-dimethyl-4-oxopyrrolidine-1-carboxylate
CAS 1152110-90-1C14H17NO3
1-Benzyl 3-methyl 4-oxopyrrolidine-1,3-dicarboxylate chemical structure, C14H15NO5, CAS 1400580-39-3
1-Benzyl 3-methyl 4-oxopyrrolidine-1,3-dicarboxylate
CAS 1400580-39-3C14H15NO5
Benzyl 2-methyl-3-oxopyrrolidine-1-carboxylate chemical structure, C13H15NO3, CAS 1823462-80-1
Benzyl 2-methyl-3-oxopyrrolidine-1-carboxylate
CAS 1823462-80-1C13H15NO3