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Murcko scaffold

Pyrazine, 2-phenyl- scaffold

905 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
905
With full pages
0
Scaffold SMILES

c1ccc(-c2cnccn2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Pyrazine, 2-phenyl- page
Murcko scaffold c1ccc(-c2cnccn2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 96 of 905 chemicals

3-Chloro-6-phenylpyrazine-2-carbonitrile chemical structure, C11H6ClN3, CAS 181284-41-3
3-Chloro-6-phenylpyrazine-2-carbonitrile
CAS 181284-41-3C11H6ClN3
Ethyl 4-(pyrazin-2-yl)benzoate chemical structure, C13H12N2O2, CAS 259541-94-1
Ethyl 4-(pyrazin-2-yl)benzoate
CAS 259541-94-1C13H12N2O2
6-Chloro-3-(2,3,5-trichlorophenyl)pyrazin-2-amine chemical structure, C10H5Cl4N3, CAS 212779-23-2
6-Chloro-3-(2,3,5-trichlorophenyl)pyrazin-2-amine
CAS 212779-23-2C10H5Cl4N3
3-Methoxy-5-phenylpyrazin-2-amine chemical structure, C11H11N3O, CAS 67602-06-6
3-Methoxy-5-phenylpyrazin-2-amine
CAS 67602-06-6C11H11N3O
2-Bromo-3-phenylpyrazine chemical structure, C10H7BrN2, CAS 2882-17-9
2-Bromo-3-phenylpyrazine
CAS 2882-17-9C10H7BrN2
2-Chloro-6-(4-methoxyphenyl)pyrazine chemical structure, C11H9ClN2O, CAS 850221-79-3
2-Chloro-6-(4-methoxyphenyl)pyrazine
CAS 850221-79-3C11H9ClN2O
2-(4-Methoxyphenyl)pyrazine chemical structure, C11H10N2O, CAS 108030-81-5
2-(4-Methoxyphenyl)pyrazine
CAS 108030-81-5C11H10N2O
2-(4-Bromophenyl)pyrazine chemical structure, C10H7BrN2, CAS 143526-49-2
2-(4-Bromophenyl)pyrazine
CAS 143526-49-2C10H7BrN2
2,3-Pyrazinedicarbonitrile, 5-(bromomethyl)-6-phenyl- chemical structure, C13H7BrN4, CAS 204192-10-9
2,3-Pyrazinedicarbonitrile, 5-(bromomethyl)-6-phenyl-
CAS 204192-10-9C13H7BrN4
4-Pyrazin-2-ylbenzoic acid chemical structure, C11H8N2O2, CAS 216060-23-0
4-Pyrazin-2-ylbenzoic acid
CAS 216060-23-0C11H8N2O2
2-(o-Tolyl)pyrazine chemical structure, C11H10N2, CAS 87537-41-5
2-(o-Tolyl)pyrazine
CAS 87537-41-5C11H10N2
2-(2-Methoxyphenyl)pyrazine chemical structure, C11H10N2O, CAS 251933-26-3
2-(2-Methoxyphenyl)pyrazine
CAS 251933-26-3C11H10N2O
Pyrazinecarboxylic acid, 3-amino-6-phenyl-, hydrazide chemical structure, C11H11N5O, CAS 438190-84-2
Pyrazinecarboxylic acid, 3-amino-6-phenyl-, hydrazide
CAS 438190-84-2C11H11N5O
3-Amino-6-(3-aminophenyl)-N-ethyl-2-pyrazinecarboxamid chemical structure, C13H15N5O, CAS 625460-32-4
3-Amino-6-(3-aminophenyl)-N-ethyl-2-pyrazinecarboxamid
CAS 625460-32-4C13H15N5O
3-Amino-6-(4-ethoxyphenyl)-2-pyrazinecarboxamide chemical structure, C13H14N4O2, CAS 625459-51-0
3-Amino-6-(4-ethoxyphenyl)-2-pyrazinecarboxamide
CAS 625459-51-0C13H14N4O2
Pyrazine, phenyl-, 4-oxide chemical structure, C10H8N2O, CAS 58861-94-2
Pyrazine, phenyl-, 4-oxide
CAS 58861-94-2C10H8N2O
N-(5-Phenyl-2-pyrazinyl)acetamide chemical structure, C12H11N3O, CAS 19953-59-4
N-(5-Phenyl-2-pyrazinyl)acetamide
CAS 19953-59-4C12H11N3O
2-Fluoro-6-phenylpyrazine chemical structure, C10H7FN2, CAS 604785-94-6
2-Fluoro-6-phenylpyrazine
CAS 604785-94-6C10H7FN2
2,5-Dichloro-3-phenylpyrazine chemical structure, C10H6Cl2N2, CAS 64163-09-3
2,5-Dichloro-3-phenylpyrazine
CAS 64163-09-3C10H6Cl2N2
2,5-Dibromo-3-phenylpyrazine chemical structure, C10H6Br2N2, CAS 64163-10-6
2,5-Dibromo-3-phenylpyrazine
CAS 64163-10-6C10H6Br2N2
Pyrazine, 3,5-dichloro-2-phenyl- chemical structure, C10H6Cl2N2, CAS 64163-11-7
Pyrazine, 3,5-dichloro-2-phenyl-
CAS 64163-11-7C10H6Cl2N2
2-Chloro-1-oxo-5-phenyl-1lambda~5~-pyrazine chemical structure, C10H7ClN2O, CAS 61578-11-8
2-Chloro-1-oxo-5-phenyl-1lambda~5~-pyrazine
CAS 61578-11-8C10H7ClN2O
5-Chloro-1-oxo-2-phenyl-1lambda~5~-pyrazine chemical structure, C10H7ClN2O, CAS 61578-12-9
5-Chloro-1-oxo-2-phenyl-1lambda~5~-pyrazine
CAS 61578-12-9C10H7ClN2O
5-(4-Methylphenyl)pyrazine-2,3-dicarbonitrile chemical structure, C13H8N4, CAS 67823-06-7
5-(4-Methylphenyl)pyrazine-2,3-dicarbonitrile
CAS 67823-06-7C13H8N4